UHRF1 Target & Gene Products-cDNA ORF clones/siRNA/antibody/protein

Explore UHRF1 gene products and cross-species research data at TarMart platform. Discover comprehensive biological information, expression tools, and therapeutic insights for Homo sapiens (human), Cynomolgus monkeys, rodents (mouse/rat), canines, felines, bovines, and equines. Your premier destination for multi-species gene research solutions
Target sublocation: Introcelluar Protein.
This gene encodes a member of a subfamily of RING-finger type E3 ubiquitin ligases. The protein binds to specific DNA sequences, and recruits a histone deacetylase to regulate gene expression. Its expression peaks at late G1 phase and continues during G2 and M phases of the cell cycle. It plays a major role in the G1/S transition by regulating topoisomerase IIalpha and retinoblastoma gene expression, and functions in the p53-dependent DNA damage checkpoint. It is regarded as a hub protein for the integration of epigenetic information. This gene is up-regulated in various cancers, and it is therefore considered to be a therapeutic target. Multiple transcript variants encoding different isoforms have been found for this gene. A related pseudogene exists on chromosome 12. [provided by RefSeq, Feb 2014]

Target ID	GM-IP7797
Target Name	UHRF1
Gene Group ldentifer （Target Gene ID in Homo species)	29128
Gene ID	100062347 (Equus caballus), 18140 (Mus musculus), 29128 (Homo sapiens), 316129 (Rattus norvegicus) 530411 (Bos taurus), 611463 (Canis lupus familiaris), 695531 (Macaca mulatta)
Target Alternative Names	Ac2-121,E3 ubiquitin-protein ligase UHRF1,ICBP90,Inverted CCAAT box-binding protein of 90 kDa,Np95,Nuclear protein 95,Nuclear zinc finger protein Np95 (HuNp95,RING finger protein 106,RING-type E3 ubiquitin transferase UHRF1,RNF106,TDRD22,Transcription factor ICBP90,UHRF1,Ubiquitin-like PHD and RING finger domain-containing protein 1 (hUHRF1),Ubiquitin-like-containing PHD and RING finger domains protein 1,Uhrf1,hNP95,hNp95),hUHRF1,huNp95
Uniprot Accession	Q8VDF2,Q96T88,Q7TPK1,A7E320
Protein Sub-location	Introcelluar Protein
Category	Life Science Target
Disease	cancer
Gene Ensembl	ENSECAG00000013193, ENSMUSG00000001228, ENSG00000276043, ENSBTAG00000002224, ENSCAFG00845014196, ENSMMUG00000012705

Pre-made viral vector of UHRF1 cDNA Clones/ORF Plasmid

Cat No.	Product Name	NMID	GeneID	Species	Type	Marker	Fusion Tag	Promoter	Detail
pGMLV000341	Human UHRF1/hNP95/hUHRF1 Lentivirus plasmid	NM_001290051.1	29128	Human	Lentivirus plasmid	ZsGreen	3xflag (C-Terminal)	CMV	Detail
pGMLV000488	Human UHRF1/hNP95/hUHRF1 Lentivirus plasmid	NM_001290051.1	29128	Human	Lentivirus plasmid	ZsGreen	3xflag (C-Terminal)	CMV	Detail
pGMAD000649	Human UHRF1/hNP95/hUHRF1 Adenovirus plasmid	NM_001048201.2	29128	Human	Adenovirus plasmid	GFP	3xflag (C-Terminal)	EF1	Detail
vGMLV000341	Human UHRF1/hNP95/hUHRF1 Lentivirus particle	NM_001290051.1	29128	Human	Lentivirus particle	ZsGreen	3xflag (C-Terminal)	CMV	Detail
vGMLV000488	Human UHRF1/hNP95/hUHRF1 Lentivirus particle	NM_001290051.1	29128	Human	Lentivirus particle	ZsGreen	3xflag (C-Terminal)	CMV	Detail
vGMAD000649	Human UHRF1/hNP95/hUHRF1 Adenovirus particle	NM_001048201.2	29128	Human	Adenovirus particle	GFP	3xflag (C-Terminal)	EF1	Detail
pGMLV001356	Mouse Uhrf1/AL022808/ICBP Lentivirus plasmid	NM_010931	18140	Mouse	Lentivirus plasmid	ZsGreen	3xflag (C-Terminal)	CMV	Detail
pGMPC000077	Mouse Uhrf1/AL022808/ICBP90 Mammalian (Non-Viral Vector) plasmid	NM_010931	18140	Mouse	Mammalian (Non-Viral Vector) plasmid	ZsGreen	Null	CMV	Detail
vGMLV001356	Mouse Uhrf1/AL022808/ICBP Lentivirus particle	NM_010931	18140	Mouse	Lentivirus particle	ZsGreen	3xflag (C-Terminal)	CMV	Detail

UHRF1 siRNA/miRNA/oligo for RNA interfence (RNAi)

Cat No.	Product Name	GeneID	Species	Grade	Detail
pGMoligo29128	Pre-made Human UHRF1/Np95/hNP95 siRNA oligo Duplex	29128	Human	In-vitro grade; in-vivo grade	Detail
pGMoligo316129	Pre-made Rat Uhrf1/Np95/Ac2-121 siRNA oligo Duplex	316129	Rat	In-vitro grade; in-vivo grade	Detail
pGMoligo18140	Pre-made Mouse Uhrf1/Np95/ICBP90 siRNA oligo Duplex	18140	Mouse	In-vitro grade; in-vivo grade	Detail
pGMoligo695531	Pre-made Cynomolgus/Rhesus macaque UHRF1 siRNA oligo Duplex	695531	Cynomolgus/Rhesus macaque	In-vitro grade; in-vivo grade	Detail
pGMoligo611463	Pre-made Dog/Canine UHRF1 siRNA oligo Duplex	611463	Dog/Canine	In-vitro grade; in-vivo grade	Detail
pGMoligo530411	Pre-made Bovines/Cattle UHRF1 siRNA oligo Duplex	530411	Bovines/Cattle	In-vitro grade; in-vivo grade	Detail
pGMoligo100062347	Pre-made Equine/Horse UHRF1 siRNA oligo Duplex	100062347	Equine/Horse	In-vitro grade; in-vivo grade	Detail

UHRF1 antibody/GMab

Cat No.	Species	Antibody Name	Format	Detail
GM-Tg-hg-IP7797-Ab	Human	Anti-Human UHRF1 monoclonal antibody	mab	Detail
GM-Tg-rg-IP7797-Ab	Rat	Anti-Rat UHRF1 monoclonal antibody	mab	Detail
GM-Tg-mg-IP7797-Ab	Mouse	Anti-Mouse UHRF1 monoclonal antibody	mab	Detail
GM-Tg-cynog-IP7797-Ab	Cynomolgus/Rhesus macaque	Anti-Cynomolgus/Rhesus macaque UHRF1 monoclonal antibody	mab	Detail
GM-Tg-cang-IP7797-Ab	Dog/Canine	Anti-Dog/Canine UHRF1 monoclonal antibody	mab	Detail
GM-Tg-bovg-IP7797-Ab	Bovines/Cattle	Anti-Bovines/Cattle UHRF1 monoclonal antibody	mab	Detail
GM-Tg-equg-IP7797-Ab	Equine/Horse	Anti-Equine/Horse UHRF1 monoclonal antibody	mab	Detail

UHRF1 recombinant protein

Cat No.	Species	Antigen Name	Expression Platform	Detail
GM-Tg-hg-IP7797-Ag	Human	Human UHRF1 recombinant protein	Mammalian cell	Detail
GM-Tg-rg-IP7797-Ag	Rat	Rat UHRF1 recombinant protein	Mammalian cell	Detail
GM-Tg-mg-IP7797-Ag	Mouse	Mouse UHRF1 recombinant protein	Mammalian cell	Detail
GM-Tg-cynog-IP7797-Ag	Cynomolgus/Rhesus macaque	Cynomolgus/Rhesus macaque UHRF1 recombinant protein	Mammalian cell	Detail
GM-Tg-cang-IP7797-Ag	Dog/Canine	Dog/Canine UHRF1 recombinant protein	Mammalian cell	Detail
GM-Tg-bovg-IP7797-Ag	Bovines/Cattle	Bovines/Cattle UHRF1 recombinant protein	Mammalian cell	Detail
GM-Tg-equg-IP7797-Ag	Equine/Horse	Equine/Horse UHRF1 recombinant protein	Mammalian cell	Detail