NEDD4L Target & Gene Products-cDNA ORF clones/siRNA/antibody/protein

Explore NEDD4L gene products and cross-species research data at TarMart platform. Discover comprehensive biological information, expression tools, and therapeutic insights for Homo sapiens (human), Cynomolgus monkeys, rodents (mouse/rat), canines, felines, bovines, and equines. Your premier destination for multi-species gene research solutions
Target sublocation: Introcelluar Protein.
This gene encodes a member of the Nedd4 family of HECT domain E3 ubiquitin ligases. HECT domain E3 ubiquitin ligases transfer ubiquitin from E2 ubiquitin-conjugating enzymes to protein substrates, thus targeting specific proteins for lysosomal degradation. The encoded protein mediates the ubiquitination of multiple target substrates and plays a critical role in epithelial sodium transport by regulating the cell surface expression of the epithelial sodium channel, ENaC. Single nucleotide polymorphisms in this gene may be associated with essential hypertension. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Mar 2012]

Target ID	GM-IP6833
Target Name	NEDD4L
Gene Group ldentifer （Target Gene ID in Homo species)	23327
Gene ID	100054395 (Equus caballus), 101088369 (Felis catus), 23327 (Homo sapiens), 291553 (Rattus norvegicus) 476189 (Canis lupus familiaris), 510003 (Bos taurus), 700282 (Macaca mulatta), 83814 (Mus musculus)
Target Alternative Names	1300012C07Rik,E3 ubiquitin-protein ligase NEDD4-like,HECT-type E3 ubiquitin transferase NED4L,NEDD4,NEDD4-2,NEDD4.2,NEDD4L,Nedd4-2,Nedd4b,Nedd4l,PVNH7,RSP5,hNEDD4-2
Uniprot Accession	Q96PU5,Q8CFI0
Protein Sub-location	Introcelluar Protein
Category	Life Science Target
Gene Ensembl	ENSECAG00000000751, ENSG00000049759, ENSCAFG00845001211, ENSBTAG00000005412, ENSMMUG00000006616, ENSMUSG00000024589

Pre-made viral vector of NEDD4L cDNA Clones/ORF Plasmid

Cat No.	Product Name	NMID	GeneID	Species	Type	Marker	Fusion Tag	Promoter	Detail
pGMLV001878	Human NEDD4L/hNEDD4-2/NEDD4-2 Lentivirus plasmid	NM_001144967.3	23327	Human	Lentivirus plasmid	ZsGreen	3xflag (C-Terminal)	CMV	Detail
pGMLV002128	Human NEDD4L/hNEDD4-2/NEDD4-2 Lentivirus plasmid	NM_001144967.3	23327	Human	Lentivirus plasmid	mCherry	3xflag (C-Terminal)	CMV	Detail
pGMAD001039	Human NEDD4L/hNEDD4-2/NEDD4-2 Adenovirus plasmid	NM_001144967.3	23327	Human	Adenovirus plasmid	EGFP	3xflag (C-Terminal)	EF1	Detail
vGMLV001878	Human NEDD4L/hNEDD4-2/NEDD4-2 Lentivirus particle	NM_001144967.3	23327	Human	Lentivirus particle	ZsGreen	3xflag (C-Terminal)	CMV	Detail
vGMLV002128	Human NEDD4L/hNEDD4-2/NEDD4-2 Lentivirus particle	NM_001144967.3	23327	Human	Lentivirus particle	mCherry	3xflag (C-Terminal)	CMV	Detail
vGMAD001039	Human NEDD4L/hNEDD4-2/NEDD4-2 Adenovirus particle	NM_001144967.3	23327	Human	Adenovirus particle	EGFP	3xflag (C-Terminal)	EF1	Detail
pGMAAV001443	Mouse Nedd4l/1300012C07Rik/Nedd4-2 Adeno-associate virus(AAV) plasmid	NM_001114386.2	83814	Mouse	Adeno-associate virus(AAV) plasmid	Null	3xflag (C-Terminal)	TIE	Detail
vGMAAV001443	Mouse Nedd4l/1300012C07Rik/Nedd4-2 Adeno-associate virus(AAV) particle	NM_001114386.2	83814	Mouse	Adeno-associate virus(AAV) particle	Null	3xflag (C-Terminal)	TIE	Detail

NEDD4L siRNA/miRNA/oligo for RNA interfence (RNAi)

Cat No.	Product Name	GeneID	Species	Grade	Detail
pGMoligo23327	Pre-made Human NEDD4L/RSP5/PVNH7 siRNA oligo Duplex	23327	Human	In-vitro grade; in-vivo grade	Detail
pGMoligo291553	Pre-made Rat Nedd4l/Nedd4-2 siRNA oligo Duplex	291553	Rat	In-vitro grade; in-vivo grade	Detail
pGMoligo83814	Pre-made Mouse Nedd4l/Nedd4b/NEDD4.2 siRNA oligo Duplex	83814	Mouse	In-vitro grade; in-vivo grade	Detail
pGMoligo700282	Pre-made Cynomolgus/Rhesus macaque NEDD4L siRNA oligo Duplex	700282	Cynomolgus/Rhesus macaque	In-vitro grade; in-vivo grade	Detail
pGMoligo101088369	Pre-made Cat/Feline NEDD4L siRNA oligo Duplex	101088369	Cat/Feline	In-vitro grade; in-vivo grade	Detail
pGMoligo476189	Pre-made Dog/Canine NEDD4L siRNA oligo Duplex	476189	Dog/Canine	In-vitro grade; in-vivo grade	Detail
pGMoligo510003	Pre-made Bovines/Cattle NEDD4L/NEDD4 siRNA oligo Duplex	510003	Bovines/Cattle	In-vitro grade; in-vivo grade	Detail
pGMoligo100054395	Pre-made Equine/Horse NEDD4L siRNA oligo Duplex	100054395	Equine/Horse	In-vitro grade; in-vivo grade	Detail

NEDD4L antibody/GMab

Cat No.	Species	Antibody Name	Format	Detail
GM-Tg-hg-IP6833-Ab	Human	Anti-Human NEDD4L monoclonal antibody	mab	Detail
GM-Tg-rg-IP6833-Ab	Rat	Anti-Rat NEDD4L monoclonal antibody	mab	Detail
GM-Tg-mg-IP6833-Ab	Mouse	Anti-Mouse NEDD4L monoclonal antibody	mab	Detail
GM-Tg-cynog-IP6833-Ab	Cynomolgus/Rhesus macaque	Anti-Cynomolgus/Rhesus macaque NEDD4L monoclonal antibody	mab	Detail
GM-Tg-felg-IP6833-Ab	Cat/Feline	Anti-Cat/Feline NEDD4L monoclonal antibody	mab	Detail
GM-Tg-cang-IP6833-Ab	Dog/Canine	Anti-Dog/Canine NEDD4L monoclonal antibody	mab	Detail
GM-Tg-bovg-IP6833-Ab	Bovines/Cattle	Anti-Bovines/Cattle NEDD4L monoclonal antibody	mab	Detail
GM-Tg-equg-IP6833-Ab	Equine/Horse	Anti-Equine/Horse NEDD4L monoclonal antibody	mab	Detail

NEDD4L recombinant protein

Cat No.	Species	Antigen Name	Expression Platform	Detail
GM-Tg-hg-IP6833-Ag	Human	Human NEDD4L recombinant protein	Mammalian cell	Detail
GM-Tg-rg-IP6833-Ag	Rat	Rat NEDD4L recombinant protein	Mammalian cell	Detail
GM-Tg-mg-IP6833-Ag	Mouse	Mouse NEDD4L recombinant protein	Mammalian cell	Detail
GM-Tg-cynog-IP6833-Ag	Cynomolgus/Rhesus macaque	Cynomolgus/Rhesus macaque NEDD4L recombinant protein	Mammalian cell	Detail
GM-Tg-felg-IP6833-Ag	Cat/Feline	Cat/Feline NEDD4L recombinant protein	Mammalian cell	Detail
GM-Tg-cang-IP6833-Ag	Dog/Canine	Dog/Canine NEDD4L recombinant protein	Mammalian cell	Detail
GM-Tg-bovg-IP6833-Ag	Bovines/Cattle	Bovines/Cattle NEDD4L recombinant protein	Mammalian cell	Detail
GM-Tg-equg-IP6833-Ag	Equine/Horse	Equine/Horse NEDD4L recombinant protein	Mammalian cell	Detail