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insights for Homo sapiens (human), Cynomolgus monkeys, rodents
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Target
sublocation: Introcelluar Protein.
Fructose-1,6-bisphosphate aldolase (EC 4.1.2.13) is a tetrameric glycolytic enzyme that catalyzes the reversible conversion of fructose-1,6-bisphosphate to glyceraldehyde 3-phosphate and dihydroxyacetone phosphate. Vertebrates have 3 aldolase isozymes which are distinguished by their electrophoretic and catalytic properties. Differences indicate that aldolases A, B, and C are distinct proteins, the products of a family of related 'housekeeping' genes exhibiting developmentally regulated expression of the different isozymes. The developing embryo produces aldolase A, which is produced in even greater amounts in adult muscle where it can be as much as 5% of total cellular protein. In adult liver, kidney and intestine, aldolase A expression is repressed and aldolase B is produced. In brain and other nervous tissue, aldolase A and C are expressed about equally. There is a high degree of homology between aldolase A and C. Defects in ALDOB cause hereditary fructose intolerance. [provided by RefSeq, Dec 2008]
| Target ID |
GM-IP6624
|
| Target Name |
ALDOB
|
Gene Group ldentifer (Target Gene ID in Homo
species)
|
229
|
| Gene ID |
100054480 (Equus caballus), 101097025 (Felis catus), 229 (Homo sapiens), 230163 (Mus musculus) 24190 (Rattus norvegicus), 474787 (Canis lupus familiaris), 515263 (Bos taurus), 713818 (Macaca mulatta)
|
| Target Alternative Names |
ALDB,ALDO2,ALDOB,Aldo-2,Aldo2,Aldob,Fructose-bisphosphate aldolase B,LIV10,Liver-type aldolase
|
| Uniprot Accession |
P05062,Q91Y97,P00884,Q3T0S5
|
| Protein Sub-location |
Introcelluar Protein
|
| Category |
Life Science Target
|
| Gene Ensembl |
ENSECAG00000015932, ENSG00000136872, ENSMUSG00000028307, ENSCAFG00845009188, ENSBTAG00000015358, ENSMMUG00000023796
|
Pre-made viral vector of ALDOB cDNA Clones/ORF Plasmid
ALDOB siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo229 | Pre-made Human ALDOB/ALDB/ALDO2 siRNA oligo Duplex | 229 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo24190 | Pre-made Rat Aldob/Aldo2/LIV10 siRNA oligo Duplex | 24190 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo230163 | Pre-made Mouse Aldob/Aldo2/Aldo-2 siRNA oligo Duplex | 230163 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo713818 | Pre-made Cynomolgus/Rhesus macaque ALDOB siRNA oligo Duplex | 713818 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101097025 | Pre-made Cat/Feline ALDOB siRNA oligo Duplex | 101097025 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo474787 | Pre-made Dog/Canine ALDOB siRNA oligo Duplex | 474787 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo515263 | Pre-made Bovines/Cattle ALDOB siRNA oligo Duplex | 515263 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100054480 | Pre-made Equine/Horse ALDOB siRNA oligo Duplex | 100054480 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
ALDOB antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-IP6624-Ab | Human | Anti-Human ALDOB monoclonal antibody | mab | | Detail |
| GM-Tg-rg-IP6624-Ab | Rat | Anti-Rat ALDOB monoclonal antibody | mab | | Detail |
| GM-Tg-mg-IP6624-Ab | Mouse | Anti-Mouse ALDOB monoclonal antibody | mab | | Detail |
| GM-Tg-cynog-IP6624-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque ALDOB monoclonal antibody | mab | | Detail |
| GM-Tg-felg-IP6624-Ab | Cat/Feline | Anti-Cat/Feline ALDOB monoclonal antibody | mab | | Detail |
| GM-Tg-cang-IP6624-Ab | Dog/Canine | Anti-Dog/Canine ALDOB monoclonal antibody | mab | | Detail |
| GM-Tg-bovg-IP6624-Ab | Bovines/Cattle | Anti-Bovines/Cattle ALDOB monoclonal antibody | mab | | Detail |
| GM-Tg-equg-IP6624-Ab | Equine/Horse | Anti-Equine/Horse ALDOB monoclonal antibody | mab | | Detail |
ALDOB recombinant protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-IP6624-Ag | Human | Human ALDOB recombinant protein | Mammalian cell | Detail |
| GM-Tg-rg-IP6624-Ag | Rat | Rat ALDOB recombinant protein | Mammalian cell | Detail |
| GM-Tg-mg-IP6624-Ag | Mouse | Mouse ALDOB recombinant protein | Mammalian cell | Detail |
| GM-Tg-cynog-IP6624-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque ALDOB recombinant protein | Mammalian cell | Detail |
| GM-Tg-felg-IP6624-Ag | Cat/Feline | Cat/Feline ALDOB recombinant protein | Mammalian cell | Detail |
| GM-Tg-cang-IP6624-Ag | Dog/Canine | Dog/Canine ALDOB recombinant protein | Mammalian cell | Detail |
| GM-Tg-bovg-IP6624-Ag | Bovines/Cattle | Bovines/Cattle ALDOB recombinant protein | Mammalian cell | Detail |
| GM-Tg-equg-IP6624-Ag | Equine/Horse | Equine/Horse ALDOB recombinant protein | Mammalian cell | Detail |