Explore HBG2 gene products and cross-species
research data at TarMart platform. Discover comprehensive
biological information, expression tools, and therapeutic
insights for Homo sapiens (human), Cynomolgus monkeys, rodents
(mouse/rat), canines, felines, bovines, and equines. Your
premier destination for multi-species gene research solutions
Target
sublocation: Introcelluar Protein.
The gamma globin genes (HBG1 and HBG2) are normally expressed in the fetal liver, spleen and bone marrow. Two gamma chains together with two alpha chains constitute fetal hemoglobin (HbF) which is normally replaced by adult hemoglobin (HbA) at birth. In some beta-thalassemias and related conditions, gamma chain production continues into adulthood. The two types of gamma chains differ at residue 136 where glycine is found in the G-gamma product (HBG2) and alanine is found in the A-gamma product (HBG1). The former is predominant at birth. The order of the genes in the beta-globin cluster is: 5'- epsilon -- gamma-G -- gamma-A -- delta -- beta--3'. [provided by RefSeq, Jul 2008]
| Target ID |
GM-IP2887
|
| Target Name |
HBG2
|
Gene Group ldentifer
（Target Gene ID in Homo
species)
|
3048
|
| Gene ID |
114672349 (Macaca mulatta), 3048 (Homo sapiens)
|
| Target Alternative Names |
Gamma-2-globin,HBG-T1,HBG2,Hb F Ggamma,Hemoglobin gamma-2 chain,Hemoglobin gamma-G chain,Hemoglobin subunit gamma-2,TNCY
|
| Uniprot Accession |
P69892
|
| Protein Sub-location |
Introcelluar Protein
|
| Disease |
maternal health, Reduced oxygen carrying capacity
|
| Gene Ensembl |
ENSG00000196565
|
Pre-made viral vector of HBG2 cDNA Clones/ORF Plasmid
HBG2 siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo3048 | Pre-made Human HBG2/TNCY/HBG-T1 siRNA oligo Duplex | 3048 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo114672349 | Pre-made Cynomolgus/Rhesus macaque HBG2 siRNA oligo Duplex | 114672349 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
HBG2 antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-IP2887-Ab | Human | Anti-Human HBG2 monoclonal antibody | mab | | Detail |
| GM-Tg-cynog-IP2887-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque HBG2 monoclonal antibody | mab | | Detail |
HBG2 recombinant protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-IP2887-Ag | Human | Human HBG2 recombinant protein | Mammalian cell | Detail |
| GM-Tg-cynog-IP2887-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque HBG2 recombinant protein | Mammalian cell | Detail |
