Explore PPP3R1 gene products and cross-species
research data at TarMart platform. Discover comprehensive
biological information, expression tools, and therapeutic
insights for Homo sapiens (human), Cynomolgus monkeys, rodents
(mouse/rat), canines, felines, bovines, and equines. Your
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Target
sublocation: Introcelluar Protein.
Enables cyclosporin A binding activity; phosphatase binding activity; and protein domain specific binding activity. Involved in calcineurin-NFAT signaling cascade and positive regulation of transcription by RNA polymerase II. Part of calcineurin complex. Implicated in Alzheimer's disease and dilated cardiomyopathy. [provided by Alliance of Genome Resources, Apr 2022]
| Target ID |
GM-IP2669
|
| Target Name |
PPP3R1
|
Gene Group ldentifer
（Target Gene ID in Homo
species)
|
5534
|
| Gene ID |
100061874 (Equus caballus), 100428682 (Macaca mulatta), 101090344 (Felis catus), 19058 (Mus musculus)
282321 (Bos taurus), 29748 (Rattus norvegicus), 5534 (Homo sapiens), 612559 (Canis lupus familiaris)
|
| Target Alternative Names |
CALNB1,CNB,CNB1,CaNB1,Calcineurin subunit B type 1,Cnb1,MCIP1,PPP3R1,Ppp3r1,Protein phosphatase 2B regulatory subunit 1,Protein phosphatase 3 regulatory subunit B alpha isoform 1
|
| Uniprot Accession |
Q63810,P63099,P63100,P63098
|
| Protein Sub-location |
Introcelluar Protein
|
| Disease from KEGG |
MAPK signaling pathway, Calcium signaling pathway, cGMP-PKG signaling pathway, Cellular senescence, Wnt signaling pathway, Axon guidance, Osteoclast differentiation, C-type lectin receptor signaling pathway, Natural killer cell mediated cytotoxicity, Th1 and Th2 cell differentiation, Th17 cell differentiation, T cell receptor signaling pathway, B cell receptor signaling pathway, Long-term potentiation, Glutamatergic synapse, Oxytocin signaling pathway, Renin secretion, Alzheimer disease, Amphetamine addiction, Tuberculosis, Human cytomegalovirus infection, Human T-cell leukemia virus 1 infection, Kaposi sarcoma-associated herpesvirus infection, PD-L1 expression and PD-1 checkpoint pathway in cancer, Lipid and atherosclerosis
|
| Gene Ensembl |
ENSECAG00000009627, ENSMMUG00000046264, ENSMUSG00000033953, ENSBTAG00000010619, ENSG00000221823, ENSCAFG00845022977
|
Pre-made viral vector of PPP3R1 cDNA Clones/ORF Plasmid
PPP3R1 siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo5534 | Pre-made Human PPP3R1/CNB/CNB1 siRNA oligo Duplex | 5534 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo29748 | Pre-made Rat Ppp3r1 siRNA oligo Duplex | 29748 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo19058 | Pre-made Mouse Ppp3r1/Cnb1/CaNB1 siRNA oligo Duplex | 19058 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100428682 | Pre-made Cynomolgus/Rhesus macaque PPP3R1 siRNA oligo Duplex | 100428682 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101090344 | Pre-made Cat/Feline PPP3R1 siRNA oligo Duplex | 101090344 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo612559 | Pre-made Dog/Canine PPP3R1 siRNA oligo Duplex | 612559 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo282321 | Pre-made Bovines/Cattle PPP3R1 siRNA oligo Duplex | 282321 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100061874 | Pre-made Equine/Horse PPP3R1 siRNA oligo Duplex | 100061874 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
PPP3R1 antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-IP2669-Ab | Human | Anti-Human PPP3R1 monoclonal antibody | mab | | Detail |
| GM-Tg-rg-IP2669-Ab | Rat | Anti-Rat PPP3R1 monoclonal antibody | mab | | Detail |
| GM-Tg-mg-IP2669-Ab | Mouse | Anti-Mouse PPP3R1 monoclonal antibody | mab | | Detail |
| GM-Tg-cynog-IP2669-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque PPP3R1 monoclonal antibody | mab | | Detail |
| GM-Tg-felg-IP2669-Ab | Cat/Feline | Anti-Cat/Feline PPP3R1 monoclonal antibody | mab | | Detail |
| GM-Tg-cang-IP2669-Ab | Dog/Canine | Anti-Dog/Canine PPP3R1 monoclonal antibody | mab | | Detail |
| GM-Tg-bovg-IP2669-Ab | Bovines/Cattle | Anti-Bovines/Cattle PPP3R1 monoclonal antibody | mab | | Detail |
| GM-Tg-equg-IP2669-Ab | Equine/Horse | Anti-Equine/Horse PPP3R1 monoclonal antibody | mab | | Detail |
PPP3R1 recombinant protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-IP2669-Ag | Human | Human PPP3R1 recombinant protein | Mammalian cell | Detail |
| GM-Tg-rg-IP2669-Ag | Rat | Rat PPP3R1 recombinant protein | Mammalian cell | Detail |
| GM-Tg-mg-IP2669-Ag | Mouse | Mouse PPP3R1 recombinant protein | Mammalian cell | Detail |
| GM-Tg-cynog-IP2669-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque PPP3R1 recombinant protein | Mammalian cell | Detail |
| GM-Tg-felg-IP2669-Ag | Cat/Feline | Cat/Feline PPP3R1 recombinant protein | Mammalian cell | Detail |
| GM-Tg-cang-IP2669-Ag | Dog/Canine | Dog/Canine PPP3R1 recombinant protein | Mammalian cell | Detail |
| GM-Tg-bovg-IP2669-Ag | Bovines/Cattle | Bovines/Cattle PPP3R1 recombinant protein | Mammalian cell | Detail |
| GM-Tg-equg-IP2669-Ag | Equine/Horse | Equine/Horse PPP3R1 recombinant protein | Mammalian cell | Detail |
