Explore MTHFR gene products and cross-species
research data at TarMart platform. Discover comprehensive
biological information, expression tools, and therapeutic
insights for Homo sapiens (human), Cynomolgus monkeys, rodents
(mouse/rat), canines, felines, bovines, and equines. Your
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Target
sublocation: Introcelluar Protein.
The protein encoded by this gene catalyzes the conversion of 5,10-methylenetetrahydrofolate to 5-methyltetrahydrofolate, a co-substrate for homocysteine remethylation to methionine. Genetic variation in this gene influences susceptibility to occlusive vascular disease, neural tube defects, colon cancer and acute leukemia, and mutations in this gene are associated with methylenetetrahydrofolate reductase deficiency.[provided by RefSeq, Oct 2009]
| Target ID |
GM-IP2611
|
| Target Name |
MTHFR
|
Gene Group ldentifer
（Target Gene ID in Homo
species)
|
4524
|
| Gene ID |
100050979 (Equus caballus), 101100576 (Felis catus), 17769 (Mus musculus), 362657 (Rattus norvegicus)
4524 (Homo sapiens), 478230 (Canis lupus familiaris), 497032 (Bos taurus), 714840 (Macaca mulatta)
|
| Target Alternative Names |
MTHFR,Methylenetetrahydrofolate reductase (NADPH),Mthfr
|
| Uniprot Accession |
Q9WU20,P42898,Q5I598
|
| Protein Sub-location |
Introcelluar Protein
|
| Disease |
cancer, Lung Cancer
|
| Disease from KEGG |
Metabolic pathways, Antifolate resistance
|
| Gene Ensembl |
ENSECAG00000020032, ENSMUSG00000029009, ENSG00000177000, ENSCAFG00845002133, ENSBTAG00000020698, ENSMMUG00000007828
|
Pre-made viral vector of MTHFR cDNA Clones/ORF Plasmid
MTHFR siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo4524 | Pre-made Human MTHFR siRNA oligo Duplex | 4524 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo362657 | Pre-made Rat Mthfr siRNA oligo Duplex | 362657 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo17769 | Pre-made Mouse Mthfr siRNA oligo Duplex | 17769 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo714840 | Pre-made Cynomolgus/Rhesus macaque MTHFR siRNA oligo Duplex | 714840 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101100576 | Pre-made Cat/Feline MTHFR siRNA oligo Duplex | 101100576 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo478230 | Pre-made Dog/Canine MTHFR siRNA oligo Duplex | 478230 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo497032 | Pre-made Bovines/Cattle MTHFR siRNA oligo Duplex | 497032 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100050979 | Pre-made Equine/Horse MTHFR siRNA oligo Duplex | 100050979 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
MTHFR antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-IP2611-Ab | Human | Anti-Human MTHFR monoclonal antibody | mab | | Detail |
| GM-Tg-rg-IP2611-Ab | Rat | Anti-Rat MTHFR monoclonal antibody | mab | | Detail |
| GM-Tg-mg-IP2611-Ab | Mouse | Anti-Mouse MTHFR monoclonal antibody | mab | | Detail |
| GM-Tg-cynog-IP2611-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque MTHFR monoclonal antibody | mab | | Detail |
| GM-Tg-felg-IP2611-Ab | Cat/Feline | Anti-Cat/Feline MTHFR monoclonal antibody | mab | | Detail |
| GM-Tg-cang-IP2611-Ab | Dog/Canine | Anti-Dog/Canine MTHFR monoclonal antibody | mab | | Detail |
| GM-Tg-bovg-IP2611-Ab | Bovines/Cattle | Anti-Bovines/Cattle MTHFR monoclonal antibody | mab | | Detail |
| GM-Tg-equg-IP2611-Ab | Equine/Horse | Anti-Equine/Horse MTHFR monoclonal antibody | mab | | Detail |
MTHFR recombinant protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-IP2611-Ag | Human | Human MTHFR recombinant protein | Mammalian cell | Detail |
| GM-Tg-rg-IP2611-Ag | Rat | Rat MTHFR recombinant protein | Mammalian cell | Detail |
| GM-Tg-mg-IP2611-Ag | Mouse | Mouse MTHFR recombinant protein | Mammalian cell | Detail |
| GM-Tg-cynog-IP2611-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque MTHFR recombinant protein | Mammalian cell | Detail |
| GM-Tg-felg-IP2611-Ag | Cat/Feline | Cat/Feline MTHFR recombinant protein | Mammalian cell | Detail |
| GM-Tg-cang-IP2611-Ag | Dog/Canine | Dog/Canine MTHFR recombinant protein | Mammalian cell | Detail |
| GM-Tg-bovg-IP2611-Ag | Bovines/Cattle | Bovines/Cattle MTHFR recombinant protein | Mammalian cell | Detail |
| GM-Tg-equg-IP2611-Ag | Equine/Horse | Equine/Horse MTHFR recombinant protein | Mammalian cell | Detail |
