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Target
sublocation: Introcelluar Protein.
This gene is a member of the GLI-similar zinc finger protein family and encodes a nuclear transcription factor with five C2H2-type zinc finger domains. The protein encoded by this gene is widely expressed at low levels in the neural tube and peripheral nervous system and likely promotes neuronal differentiation. It is abundantly expressed in the kidney and may have a role in the regulation of kidney morphogenesis. p120 regulates the expression level of this protein and induces the cleavage of this protein's C-terminal zinc finger domain. This protein also promotes the nuclear translocation of p120. Mutations in this gene cause nephronophthisis (NPHP), an autosomal recessive kidney disease characterized by tubular basement membrane disruption, interstitial lymphohistiocytic cell infiltration, and development of cysts at the corticomedullary border of the kidneys.[provided by RefSeq, Jan 2010]
| Target ID |
GM-IP2526
|
| Target Name |
GLIS2
|
Gene Group ldentifer (Target Gene ID in Homo
species)
|
84662
|
| Gene ID |
100066071 (Equus caballus), 101095217 (Felis catus), 302946 (Rattus norvegicus), 490028 (Canis lupus familiaris) 527935 (Bos taurus), 708454 (Macaca mulatta), 83396 (Mus musculus), 84662 (Homo sapiens)
|
| Target Alternative Names |
GLI-similar 2,GLIS2,Gli5,Glis2,Klf16,NKL,NPHP7,Neuronal Krueppel-like protein,Nkl,Zinc finger protein GLIS2
|
| Uniprot Accession |
Q8VDL9,Q9BZE0
|
| Protein Sub-location |
Introcelluar Protein
|
| Gene Ensembl |
ENSECAG00000020639, ENSCAFG00845001353, ENSBTAG00000009199, ENSMMUG00000015758, ENSMUSG00000014303, ENSG00000126603
|
Pre-made viral vector of GLIS2 cDNA Clones/ORF Plasmid
GLIS2 siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo84662 | Pre-made Human GLIS2/NKL/NPHP7 siRNA oligo Duplex | 84662 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo302946 | Pre-made Rat Glis2 siRNA oligo Duplex | 302946 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo83396 | Pre-made Mouse Glis2/Nkl/Gli5 siRNA oligo Duplex | 83396 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo708454 | Pre-made Cynomolgus/Rhesus macaque GLIS2 siRNA oligo Duplex | 708454 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101095217 | Pre-made Cat/Feline GLIS2 siRNA oligo Duplex | 101095217 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo490028 | Pre-made Dog/Canine GLIS2 siRNA oligo Duplex | 490028 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo527935 | Pre-made Bovines/Cattle GLIS2 siRNA oligo Duplex | 527935 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100066071 | Pre-made Equine/Horse GLIS2 siRNA oligo Duplex | 100066071 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
GLIS2 antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-IP2526-Ab | Human | Anti-Human GLIS2 monoclonal antibody | mab | | Detail |
| GM-Tg-rg-IP2526-Ab | Rat | Anti-Rat GLIS2 monoclonal antibody | mab | | Detail |
| GM-Tg-mg-IP2526-Ab | Mouse | Anti-Mouse GLIS2 monoclonal antibody | mab | | Detail |
| GM-Tg-cynog-IP2526-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque GLIS2 monoclonal antibody | mab | | Detail |
| GM-Tg-felg-IP2526-Ab | Cat/Feline | Anti-Cat/Feline GLIS2 monoclonal antibody | mab | | Detail |
| GM-Tg-cang-IP2526-Ab | Dog/Canine | Anti-Dog/Canine GLIS2 monoclonal antibody | mab | | Detail |
| GM-Tg-bovg-IP2526-Ab | Bovines/Cattle | Anti-Bovines/Cattle GLIS2 monoclonal antibody | mab | | Detail |
| GM-Tg-equg-IP2526-Ab | Equine/Horse | Anti-Equine/Horse GLIS2 monoclonal antibody | mab | | Detail |
GLIS2 recombinant protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-IP2526-Ag | Human | Human GLIS2 recombinant protein | Mammalian cell | Detail |
| GM-Tg-rg-IP2526-Ag | Rat | Rat GLIS2 recombinant protein | Mammalian cell | Detail |
| GM-Tg-mg-IP2526-Ag | Mouse | Mouse GLIS2 recombinant protein | Mammalian cell | Detail |
| GM-Tg-cynog-IP2526-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque GLIS2 recombinant protein | Mammalian cell | Detail |
| GM-Tg-felg-IP2526-Ag | Cat/Feline | Cat/Feline GLIS2 recombinant protein | Mammalian cell | Detail |
| GM-Tg-cang-IP2526-Ag | Dog/Canine | Dog/Canine GLIS2 recombinant protein | Mammalian cell | Detail |
| GM-Tg-bovg-IP2526-Ag | Bovines/Cattle | Bovines/Cattle GLIS2 recombinant protein | Mammalian cell | Detail |
| GM-Tg-equg-IP2526-Ag | Equine/Horse | Equine/Horse GLIS2 recombinant protein | Mammalian cell | Detail |