DDB2 Target & Gene Products-cDNA ORF clones/siRNA/antibody/protein

Explore DDB2 gene products and cross-species research data at TarMart platform. Discover comprehensive biological information, expression tools, and therapeutic insights for Homo sapiens (human), Cynomolgus monkeys, rodents (mouse/rat), canines, felines, bovines, and equines. Your premier destination for multi-species gene research solutions
Target sublocation: Introcelluar Protein.
This gene encodes a protein that is necessary for the repair of ultraviolet light-damaged DNA. This protein is the smaller subunit of a heterodimeric protein complex that participates in nucleotide excision repair, and this complex mediates the ubiquitylation of histones H3 and H4, which facilitates the cellular response to DNA damage. This subunit appears to be required for DNA binding. Mutations in this gene cause xeroderma pigmentosum complementation group E, a recessive disease that is characterized by an increased sensitivity to UV light and a high predisposition for skin cancer development, in some cases accompanied by neurological abnormalities. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2014]

Target ID	GM-IP2450
Target Name	DDB2
Gene Group ldentifer （Target Gene ID in Homo species)	1643
Gene ID	100051180 (Equus caballus), 100362121 (Rattus norvegicus), 101092211 (Felis catus), 107986 (Mus musculus) 1643 (Homo sapiens), 483626 (Canis lupus familiaris), 519357 (Bos taurus)
Target Alternative Names	2610043A19Rik,DDB p48 subunit (DDBb),DDB2,DDBB,DNA damage-binding protein 2,Damage-specific DNA-binding protein 2,Ddb2,UV-DDB2,UV-damaged DNA-binding protein 2 (UV-DDB 2),XPE
Uniprot Accession	Q99J79,Q92466,Q0VBY8
Protein Sub-location	Introcelluar Protein
Disease	cancer
Disease from KEGG	p53 signaling pathway, Hepatitis B, Epstein-Barr virus infection, Pathways in cancer, Colorectal cancer, Pancreatic cancer, Endometrial cancer, Glioma, Thyroid cancer, Basal cell carcinoma, Melanoma, Chronic myeloid leukemia, Small cell lung cancer, Non-small cell lung cancer, Breast cancer, Hepatocellular carcinoma, Gastric cancer
Gene Ensembl	ENSECAG00000008711, ENSMUSG00000002109, ENSG00000134574, ENSCAFG00845024798, ENSBTAG00000020999
Target Classification	Tumor-associated antigen (TAA)

Pre-made viral vector of DDB2 cDNA Clones/ORF Plasmid

Cat No.	Product Name	NMID	GeneID	Species	Type	Marker	Fusion Tag	Promoter	Detail
pGMLP003996	Human DDB2 Lentivirus plasmid	BC000093	1643	Human	Lentivirus plasmid	ZsGreen	3xflag (C-Terminal)	CMV	Detail
vGMLP003996	Human DDB2 Lentivirus particle	BC000093	1643	Human	Lentivirus particle	ZsGreen	3xflag (C-Terminal)	CMV	Detail
pGMLPm005245	Mouse Ddb2/2610043A19Rik Lentivirus plasmid	NM_028119.5	107986	Mouse	Lentivirus plasmid	ZsGreen	3xflag (C-Terminal)	CMV	Detail
vGMLPm005245	Mouse Ddb2/2610043A19Rik Lentivirus particle	NM_028119.5	107986	Mouse	Lentivirus particle	ZsGreen	3xflag (C-Terminal)	CMV	Detail

DDB2 siRNA/miRNA/oligo for RNA interfence (RNAi)

Cat No.	Product Name	GeneID	Species	Grade	Detail
pGMoligo1643	Pre-made Human DDB2/XPE/DDBB siRNA oligo Duplex	1643	Human	In-vitro grade; in-vivo grade	Detail
pGMoligo100362121	Pre-made Rat Ddb2 siRNA oligo Duplex	100362121	Rat	In-vitro grade; in-vivo grade	Detail
pGMoligo107986	Pre-made Mouse Ddb2/2610043A19Rik siRNA oligo Duplex	107986	Mouse	In-vitro grade; in-vivo grade	Detail
pGMoligo101092211	Pre-made Cat/Feline DDB2 siRNA oligo Duplex	101092211	Cat/Feline	In-vitro grade; in-vivo grade	Detail
pGMoligo483626	Pre-made Dog/Canine DDB2 siRNA oligo Duplex	483626	Dog/Canine	In-vitro grade; in-vivo grade	Detail
pGMoligo519357	Pre-made Bovines/Cattle DDB2 siRNA oligo Duplex	519357	Bovines/Cattle	In-vitro grade; in-vivo grade	Detail
pGMoligo100051180	Pre-made Equine/Horse DDB2 siRNA oligo Duplex	100051180	Equine/Horse	In-vitro grade; in-vivo grade	Detail

DDB2 antibody/GMab

Cat No.	Species	Antibody Name	Format	Detail
GM-Tg-hg-IP2450-Ab	Human	Anti-Human DDB2 monoclonal antibody	mab	Detail
GM-Tg-rg-IP2450-Ab	Rat	Anti-Rat DDB2 monoclonal antibody	mab	Detail
GM-Tg-mg-IP2450-Ab	Mouse	Anti-Mouse DDB2 monoclonal antibody	mab	Detail
GM-Tg-felg-IP2450-Ab	Cat/Feline	Anti-Cat/Feline DDB2 monoclonal antibody	mab	Detail
GM-Tg-cang-IP2450-Ab	Dog/Canine	Anti-Dog/Canine DDB2 monoclonal antibody	mab	Detail
GM-Tg-bovg-IP2450-Ab	Bovines/Cattle	Anti-Bovines/Cattle DDB2 monoclonal antibody	mab	Detail
GM-Tg-equg-IP2450-Ab	Equine/Horse	Anti-Equine/Horse DDB2 monoclonal antibody	mab	Detail

DDB2 recombinant protein

Cat No.	Species	Antigen Name	Expression Platform	Detail
GM-Tg-hg-IP2450-Ag	Human	Human DDB2 recombinant protein	Mammalian cell	Detail
GM-Tg-rg-IP2450-Ag	Rat	Rat DDB2 recombinant protein	Mammalian cell	Detail
GM-Tg-mg-IP2450-Ag	Mouse	Mouse DDB2 recombinant protein	Mammalian cell	Detail
GM-Tg-felg-IP2450-Ag	Cat/Feline	Cat/Feline DDB2 recombinant protein	Mammalian cell	Detail
GM-Tg-cang-IP2450-Ag	Dog/Canine	Dog/Canine DDB2 recombinant protein	Mammalian cell	Detail
GM-Tg-bovg-IP2450-Ag	Bovines/Cattle	Bovines/Cattle DDB2 recombinant protein	Mammalian cell	Detail
GM-Tg-equg-IP2450-Ag	Equine/Horse	Equine/Horse DDB2 recombinant protein	Mammalian cell	Detail