Explore CHD8 gene products and cross-species
research data at TarMart platform. Discover comprehensive
biological information, expression tools, and therapeutic
insights for Homo sapiens (human), Cynomolgus monkeys, rodents
(mouse/rat), canines, felines, bovines, and equines. Your
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Target
sublocation: Introcelluar Protein.
This gene encodes a member of the chromodomain-helicase-DNA binding protein family, which is characterized by a SNF2-like domain and two chromatin organization modifier domains. The encoded protein also contains brahma and kismet domains, which are common to the subfamily of chromodomain-helicase-DNA binding proteins to which this protein belongs. This gene has been shown to function in several processes that include transcriptional regulation, epigenetic remodeling, promotion of cell proliferation, and regulation of RNA synthesis. Allelic variants of this gene are associated with autism spectrum disorder. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2016]
| Target ID |
GM-IP2428
|
| Target Name |
CHD8
|
Gene Group ldentifer
（Target Gene ID in Homo
species)
|
57680
|
| Gene ID |
100059337 (Equus caballus), 101097402 (Felis catus), 475401 (Canis lupus familiaris), 507111 (Bos taurus)
57680 (Homo sapiens), 65027 (Rattus norvegicus), 67772 (Mus musculus), 708169 (Macaca mulatta)
|
| Target Alternative Names |
5830451P18Rik,ATP-dependent helicase CHD8,AUTS18,CHD-8,CHD8,Chd-8,Chd8,Chromodomain-helicase-DNA-binding protein 8,Duplin,HELSNF1,Helicase with SNF2 domain 1,IDDAM,mKIAA1564
|
| Uniprot Accession |
Q9HCK8,Q9JIX5,Q09XV5
|
| Protein Sub-location |
Introcelluar Protein
|
| Disease from KEGG |
Wnt signaling pathway
|
| Gene Ensembl |
ENSECAG00000016102, ENSCAFG00845026020, ENSBTAG00000020422, ENSG00000100888, ENSMUSG00000053754, ENSMMUG00000015002
|
CHD8 siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo57680 | Pre-made Human CHD8/IDDAM/AUTS18 siRNA oligo Duplex | 57680 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo65027 | Pre-made Rat Chd8/CHD-8 siRNA oligo Duplex | 65027 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo67772 | Pre-made Mouse Chd8/Chd-8/Duplin siRNA oligo Duplex | 67772 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo708169 | Pre-made Cynomolgus/Rhesus macaque CHD8 siRNA oligo Duplex | 708169 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101097402 | Pre-made Cat/Feline CHD8 siRNA oligo Duplex | 101097402 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo475401 | Pre-made Dog/Canine CHD8 siRNA oligo Duplex | 475401 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo507111 | Pre-made Bovines/Cattle CHD8 siRNA oligo Duplex | 507111 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100059337 | Pre-made Equine/Horse CHD8 siRNA oligo Duplex | 100059337 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
CHD8 antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-IP2428-Ab | Human | Anti-Human CHD8 monoclonal antibody | mab | | Detail |
| GM-Tg-rg-IP2428-Ab | Rat | Anti-Rat CHD8 monoclonal antibody | mab | | Detail |
| GM-Tg-mg-IP2428-Ab | Mouse | Anti-Mouse CHD8 monoclonal antibody | mab | | Detail |
| GM-Tg-cynog-IP2428-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque CHD8 monoclonal antibody | mab | | Detail |
| GM-Tg-felg-IP2428-Ab | Cat/Feline | Anti-Cat/Feline CHD8 monoclonal antibody | mab | | Detail |
| GM-Tg-cang-IP2428-Ab | Dog/Canine | Anti-Dog/Canine CHD8 monoclonal antibody | mab | | Detail |
| GM-Tg-bovg-IP2428-Ab | Bovines/Cattle | Anti-Bovines/Cattle CHD8 monoclonal antibody | mab | | Detail |
| GM-Tg-equg-IP2428-Ab | Equine/Horse | Anti-Equine/Horse CHD8 monoclonal antibody | mab | | Detail |
CHD8 recombinant protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-IP2428-Ag | Human | Human CHD8 recombinant protein | Mammalian cell | Detail |
| GM-Tg-rg-IP2428-Ag | Rat | Rat CHD8 recombinant protein | Mammalian cell | Detail |
| GM-Tg-mg-IP2428-Ag | Mouse | Mouse CHD8 recombinant protein | Mammalian cell | Detail |
| GM-Tg-cynog-IP2428-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque CHD8 recombinant protein | Mammalian cell | Detail |
| GM-Tg-felg-IP2428-Ag | Cat/Feline | Cat/Feline CHD8 recombinant protein | Mammalian cell | Detail |
| GM-Tg-cang-IP2428-Ag | Dog/Canine | Dog/Canine CHD8 recombinant protein | Mammalian cell | Detail |
| GM-Tg-bovg-IP2428-Ag | Bovines/Cattle | Bovines/Cattle CHD8 recombinant protein | Mammalian cell | Detail |
| GM-Tg-equg-IP2428-Ag | Equine/Horse | Equine/Horse CHD8 recombinant protein | Mammalian cell | Detail |
