Explore Cyclin T1/CCNT1 gene products and cross-species
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Target
sublocation: Introcelluar Protein.
This gene encodes a member of the highly conserved cyclin C subfamily. The encoded protein tightly associates with cyclin-dependent kinase 9, and is a major subunit of positive transcription elongation factor b (p-TEFb). In humans, there are multiple forms of positive transcription elongation factor b, which may include one of several different cyclins along with cyclin-dependent kinase 9. The complex containing the encoded cyclin and cyclin-dependent kinase 9 acts as a cofactor of human immunodeficiency virus type 1 (HIV-1) Tat protein, and is both necessary and sufficient for full activation of viral transcription. This cyclin and its kinase partner are also involved in triggering transcript elongation through phosphorylation of the carboxy-terminal domain of the largest RNA polymerase II subunit. Overexpression of this gene is implicated in tumor growth. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Apr 2013]
| Target ID |
GM-IP13415
|
| Target Name |
Cyclin T1/CCNT1
|
Gene Group ldentifer (Target Gene ID in Homo
species)
|
904
|
| Gene ID |
100033893 (Equus caballus), 101090703 (Felis catus), 12455 (Mus musculus), 315291 (Rattus norvegicus) 407194 (Bos taurus), 486564 (Canis lupus familiaris), 707754 (Macaca mulatta), 904 (Homo sapiens)
|
| Target Alternative Names |
2810478G24Rik,CCNT,CCNT1,CYCT1,Ccnt1,CycT1,Cyclin T1,Cyclin-T,Cyclin-T1,HIVE1
|
| Uniprot Accession |
Q9XT26,Q9QWV9,Q6T8E9,O60563
|
| Protein Sub-location |
Introcelluar Protein
|
| Category |
Life Science Target
|
| Gene Ensembl |
ENSECAG00000015768, ENSMUSG00000011960, ENSBTAG00000005861, ENSCAFG00845024989, ENSMMUG00000007629, ENSG00000129315
|
Pre-made viral vector of Cyclin T1/CCNT1 cDNA Clones/ORF Plasmid
Cyclin T1/CCNT1 siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo904 | Pre-made Human CCNT1/CCNT/CYCT1 siRNA oligo Duplex | 904 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo315291 | Pre-made Rat Ccnt1 siRNA oligo Duplex | 315291 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo12455 | Pre-made Mouse Ccnt1/CycT1/2810478G24Rik siRNA oligo Duplex | 12455 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo707754 | Pre-made Cynomolgus/Rhesus macaque CCNT1/Cyclin-T1 siRNA oligo Duplex | 707754 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101090703 | Pre-made Cat/Feline CCNT1 siRNA oligo Duplex | 101090703 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo486564 | Pre-made Dog/Canine CCNT1 siRNA oligo Duplex | 486564 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo407194 | Pre-made Bovines/Cattle CCNT1 siRNA oligo Duplex | 407194 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100033893 | Pre-made Equine/Horse CCNT1/CYCT1 siRNA oligo Duplex | 100033893 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
Cyclin T1/CCNT1 antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-IP13415-Ab | Human | Anti-Human Cyclin T1/CCNT1 monoclonal antibody | mab | | Detail |
| GM-Tg-rg-IP13415-Ab | Rat | Anti-Rat Cyclin T1/CCNT1 monoclonal antibody | mab | | Detail |
| GM-Tg-mg-IP13415-Ab | Mouse | Anti-Mouse Cyclin T1/CCNT1 monoclonal antibody | mab | | Detail |
| GM-Tg-cynog-IP13415-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque Cyclin T1/CCNT1 monoclonal antibody | mab | | Detail |
| GM-Tg-felg-IP13415-Ab | Cat/Feline | Anti-Cat/Feline Cyclin T1/CCNT1 monoclonal antibody | mab | | Detail |
| GM-Tg-cang-IP13415-Ab | Dog/Canine | Anti-Dog/Canine Cyclin T1/CCNT1 monoclonal antibody | mab | | Detail |
| GM-Tg-bovg-IP13415-Ab | Bovines/Cattle | Anti-Bovines/Cattle Cyclin T1/CCNT1 monoclonal antibody | mab | | Detail |
| GM-Tg-equg-IP13415-Ab | Equine/Horse | Anti-Equine/Horse Cyclin T1/CCNT1 monoclonal antibody | mab | | Detail |
Cyclin T1/CCNT1 recombinant protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-IP13415-Ag | Human | Human Cyclin T1/CCNT1 recombinant protein | Mammalian cell | Detail |
| GM-Tg-rg-IP13415-Ag | Rat | Rat Cyclin T1/CCNT1 recombinant protein | Mammalian cell | Detail |
| GM-Tg-mg-IP13415-Ag | Mouse | Mouse Cyclin T1/CCNT1 recombinant protein | Mammalian cell | Detail |
| GM-Tg-cynog-IP13415-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque Cyclin T1/CCNT1 recombinant protein | Mammalian cell | Detail |
| GM-Tg-felg-IP13415-Ag | Cat/Feline | Cat/Feline Cyclin T1/CCNT1 recombinant protein | Mammalian cell | Detail |
| GM-Tg-cang-IP13415-Ag | Dog/Canine | Dog/Canine Cyclin T1/CCNT1 recombinant protein | Mammalian cell | Detail |
| GM-Tg-bovg-IP13415-Ag | Bovines/Cattle | Bovines/Cattle Cyclin T1/CCNT1 recombinant protein | Mammalian cell | Detail |
| GM-Tg-equg-IP13415-Ag | Equine/Horse | Equine/Horse Cyclin T1/CCNT1 recombinant protein | Mammalian cell | Detail |