FADD Target & Gene Products-cDNA ORF clones/siRNA/antibody/protein

Explore FADD gene products and cross-species research data at TarMart platform. Discover comprehensive biological information, expression tools, and therapeutic insights for Homo sapiens (human), Cynomolgus monkeys, rodents (mouse/rat), canines, felines, bovines, and equines. Your premier destination for multi-species gene research solutions
Target sublocation: Introcelluar Protein.
The protein encoded by this gene is an adaptor molecule that interacts with various cell surface receptors and mediates cell apoptotic signals. Through its C-terminal death domain, this protein can be recruited by TNFRSF6/Fas-receptor, tumor necrosis factor receptor, TNFRSF25, and TNFSF10/TRAIL-receptor, and thus it participates in the death signaling initiated by these receptors. Interaction of this protein with the receptors unmasks the N-terminal effector domain of this protein, which allows it to recruit caspase-8, and thereby activate the cysteine protease cascade. Knockout studies in mice also suggest the importance of this protein in early T cell development. [provided by RefSeq, Jul 2008]

Target ID	GM-IP13272
Target Name	FADD
Gene Group ldentifer （Target Gene ID in Homo species)	8772
Gene ID	100061802 (Equus caballus), 101087871 (Felis catus), 14082 (Mus musculus), 266610 (Rattus norvegicus) 493720 (Bos taurus), 611694 (Canis lupus familiaris), 708606 (Macaca mulatta), 8772 (Homo sapiens)
Target Alternative Names	FADD,FAS-associated death domain protein,FAS-associating death domain-containing protein,Fadd,GIG3,Growth-inhibiting gene 3 protein,IMD90,MORT1,Mediator of receptor induced toxicity,Mort1,Mort1/FADD
Uniprot Accession	Q61160,Q645M6,Q13158
Protein Sub-location	Introcelluar Protein
Category	Life Science Target
Disease	cancer
Gene Ensembl	ENSECAG00000021437, ENSMUSG00000031077, ENSBTAG00000018274, ENSCAFG00845014582, ENSG00000168040

Pre-made viral vector of FADD cDNA Clones/ORF Plasmid

Cat No.	Product Name	NMID	GeneID	Species	Type	Marker	Fusion Tag	Promoter	Detail
pGMLP000530	Human FADD/GIG3/MORT1 Lentivirus plasmid	NM_003824	8772	Human	Lentivirus plasmid	ZsGreen	3xflag (C-Terminal)	CMV	Detail
pGMAP000240	Human FADD/GIG3/MGC8528 Adenovirus plasmid	BC000334	8772	Human	Adenovirus plasmid	GFP	3xflag (C-Terminal)	EF1	Detail
vGMLP000530	Human FADD/GIG3/MORT1 Lentivirus particle	NM_003824	8772	Human	Lentivirus particle	ZsGreen	3xflag (C-Terminal)	CMV	Detail
vGMAP000240	Human FADD/GIG3/MGC8528 Adenovirus particle	BC000334	8772	Human	Adenovirus particle	GFP	3xflag (C-Terminal)	EF1	Detail
pGMLPm000368	Mouse Fadd/Mort1/FADD Lentivirus plasmid	NM_010175	14082	Mouse	Lentivirus plasmid	ZsGreen	3xflag (C-Terminal)	CMV	Detail
vGMLPm000368	Mouse Fadd/Mort1/FADD Lentivirus particle	NM_010175	14082	Mouse	Lentivirus particle	ZsGreen	3xflag (C-Terminal)	CMV	Detail

FADD siRNA/miRNA/oligo for RNA interfence (RNAi)

Cat No.	Product Name	GeneID	Species	Grade	Detail
pGMoligo8772	Pre-made Human FADD/GIG3/IMD90 siRNA oligo Duplex	8772	Human	In-vitro grade; in-vivo grade	Detail
pGMoligo266610	Pre-made Rat Fadd/Mort1 siRNA oligo Duplex	266610	Rat	In-vitro grade; in-vivo grade	Detail
pGMoligo14082	Pre-made Mouse Fadd/Mort1/FADD siRNA oligo Duplex	14082	Mouse	In-vitro grade; in-vivo grade	Detail
pGMoligo708606	Pre-made Cynomolgus/Rhesus macaque FADD siRNA oligo Duplex	708606	Cynomolgus/Rhesus macaque	In-vitro grade; in-vivo grade	Detail
pGMoligo101087871	Pre-made Cat/Feline FADD siRNA oligo Duplex	101087871	Cat/Feline	In-vitro grade; in-vivo grade	Detail
pGMoligo611694	Pre-made Dog/Canine FADD siRNA oligo Duplex	611694	Dog/Canine	In-vitro grade; in-vivo grade	Detail
pGMoligo493720	Pre-made Bovines/Cattle FADD siRNA oligo Duplex	493720	Bovines/Cattle	In-vitro grade; in-vivo grade	Detail
pGMoligo100061802	Pre-made Equine/Horse FADD siRNA oligo Duplex	100061802	Equine/Horse	In-vitro grade; in-vivo grade	Detail

FADD antibody/GMab

Cat No.	Species	Antibody Name	Format	Detail
GM-Tg-hg-IP13272-Ab	Human	Anti-Human FADD monoclonal antibody	mab	Detail
GM-Tg-rg-IP13272-Ab	Rat	Anti-Rat FADD monoclonal antibody	mab	Detail
GM-Tg-mg-IP13272-Ab	Mouse	Anti-Mouse FADD monoclonal antibody	mab	Detail
GM-Tg-cynog-IP13272-Ab	Cynomolgus/Rhesus macaque	Anti-Cynomolgus/Rhesus macaque FADD monoclonal antibody	mab	Detail
GM-Tg-felg-IP13272-Ab	Cat/Feline	Anti-Cat/Feline FADD monoclonal antibody	mab	Detail
GM-Tg-cang-IP13272-Ab	Dog/Canine	Anti-Dog/Canine FADD monoclonal antibody	mab	Detail
GM-Tg-bovg-IP13272-Ab	Bovines/Cattle	Anti-Bovines/Cattle FADD monoclonal antibody	mab	Detail
GM-Tg-equg-IP13272-Ab	Equine/Horse	Anti-Equine/Horse FADD monoclonal antibody	mab	Detail

FADD recombinant protein

Cat No.	Species	Antigen Name	Expression Platform	Detail
GM-Tg-hg-IP13272-Ag	Human	Human FADD recombinant protein	Mammalian cell	Detail
GM-Tg-rg-IP13272-Ag	Rat	Rat FADD recombinant protein	Mammalian cell	Detail
GM-Tg-mg-IP13272-Ag	Mouse	Mouse FADD recombinant protein	Mammalian cell	Detail
GM-Tg-cynog-IP13272-Ag	Cynomolgus/Rhesus macaque	Cynomolgus/Rhesus macaque FADD recombinant protein	Mammalian cell	Detail
GM-Tg-felg-IP13272-Ag	Cat/Feline	Cat/Feline FADD recombinant protein	Mammalian cell	Detail
GM-Tg-cang-IP13272-Ag	Dog/Canine	Dog/Canine FADD recombinant protein	Mammalian cell	Detail
GM-Tg-bovg-IP13272-Ag	Bovines/Cattle	Bovines/Cattle FADD recombinant protein	Mammalian cell	Detail
GM-Tg-equg-IP13272-Ag	Equine/Horse	Equine/Horse FADD recombinant protein	Mammalian cell	Detail