Explore BLM gene products and cross-species
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insights for Homo sapiens (human), Cynomolgus monkeys, rodents
(mouse/rat), canines, felines, bovines, and equines. Your
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Target
sublocation: Introcelluar Protein.
The Bloom syndrome is an autosomal recessive disorder characterized by growth deficiency, microcephaly and immunodeficiency among others. It is caused by homozygous or compound heterozygous mutation in the gene encoding DNA helicase RecQ protein on chromosome 15q26. This Bloom-associated helicase unwinds a variety of DNA substrates including Holliday junction, and is involved in several pathways contributing to the maintenance of genome stability. Identification of pathogenic Bloom variants is required for heterozygote testing in at-risk families. [provided by RefSeq, May 2020]
| Target ID |
GM-IP11106
|
| Target Name |
BLM
|
Gene Group ldentifer
（Target Gene ID in Homo
species)
|
641
|
| Gene ID |
100053387 (Equus caballus), 100685609 (Canis lupus familiaris), 101100056 (Felis catus), 12144 (Mus musculus)
308755 (Rattus norvegicus), 534148 (Bos taurus), 641 (Homo sapiens), 703460 (Macaca mulatta)
|
| Target Alternative Names |
BLM,BS,Blm,Bloom syndrome protein,DNA 3'-5' helicase BLM,DNA helicase,MGRISCE1,RECQ2,RECQL2,RECQL3,RecQ protein-like 3,RecQ-like DNA helicase BLM,RecQ-like type 2 (RecQ2)
|
| Uniprot Accession |
O88700,P54132
|
| Protein Sub-location |
Introcelluar Protein
|
| Category |
Life Science Target
|
| Disease |
cancer
|
| Gene Ensembl |
ENSECAG00000011405, ENSCAFG00845002429, ENSMUSG00000030528, ENSBTAG00000020301, ENSG00000197299, ENSMMUG00000019526
|
BLM siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo641 | Pre-made Human BLM/BS/RECQ2 siRNA oligo Duplex | 641 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo308755 | Pre-made Rat Blm siRNA oligo Duplex | 308755 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo12144 | Pre-made Mouse Blm siRNA oligo Duplex | 12144 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo703460 | Pre-made Cynomolgus/Rhesus macaque BLM siRNA oligo Duplex | 703460 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101100056 | Pre-made Cat/Feline BLM siRNA oligo Duplex | 101100056 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100685609 | Pre-made Dog/Canine BLM siRNA oligo Duplex | 100685609 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo534148 | Pre-made Bovines/Cattle BLM siRNA oligo Duplex | 534148 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100053387 | Pre-made Equine/Horse BLM siRNA oligo Duplex | 100053387 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
BLM antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-IP11106-Ab | Human | Anti-Human BLM monoclonal antibody | mab | | Detail |
| GM-Tg-rg-IP11106-Ab | Rat | Anti-Rat BLM monoclonal antibody | mab | | Detail |
| GM-Tg-mg-IP11106-Ab | Mouse | Anti-Mouse BLM monoclonal antibody | mab | | Detail |
| GM-Tg-cynog-IP11106-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque BLM monoclonal antibody | mab | | Detail |
| GM-Tg-felg-IP11106-Ab | Cat/Feline | Anti-Cat/Feline BLM monoclonal antibody | mab | | Detail |
| GM-Tg-cang-IP11106-Ab | Dog/Canine | Anti-Dog/Canine BLM monoclonal antibody | mab | | Detail |
| GM-Tg-bovg-IP11106-Ab | Bovines/Cattle | Anti-Bovines/Cattle BLM monoclonal antibody | mab | | Detail |
| GM-Tg-equg-IP11106-Ab | Equine/Horse | Anti-Equine/Horse BLM monoclonal antibody | mab | | Detail |
BLM recombinant protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-IP11106-Ag | Human | Human BLM recombinant protein | Mammalian cell | Detail |
| GM-Tg-rg-IP11106-Ag | Rat | Rat BLM recombinant protein | Mammalian cell | Detail |
| GM-Tg-mg-IP11106-Ag | Mouse | Mouse BLM recombinant protein | Mammalian cell | Detail |
| GM-Tg-cynog-IP11106-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque BLM recombinant protein | Mammalian cell | Detail |
| GM-Tg-felg-IP11106-Ag | Cat/Feline | Cat/Feline BLM recombinant protein | Mammalian cell | Detail |
| GM-Tg-cang-IP11106-Ag | Dog/Canine | Dog/Canine BLM recombinant protein | Mammalian cell | Detail |
| GM-Tg-bovg-IP11106-Ag | Bovines/Cattle | Bovines/Cattle BLM recombinant protein | Mammalian cell | Detail |
| GM-Tg-equg-IP11106-Ag | Equine/Horse | Equine/Horse BLM recombinant protein | Mammalian cell | Detail |
