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insights for Homo sapiens (human), Cynomolgus monkeys, rodents
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Target
sublocation: Introcelluar Protein.
Retention of resident soluble proteins in the lumen of the endoplasmic reticulum (ER) is achieved in both yeast and animal cells by their continual retrieval from the cis-Golgi, or a pre-Golgi compartment. Sorting of these proteins is dependent on a C-terminal tetrapeptide signal, usually lys-asp-glu-leu (KDEL) in animal cells, and his-asp-glu-leu (HDEL) in S. cerevisiae. This process is mediated by a receptor that recognizes, and binds the tetrapeptide-containing protein, and returns it to the ER. In yeast, the sorting receptor encoded by a single gene, ERD2, which is a seven-transmembrane protein. Unlike yeast, several human homologs of the ERD2 gene, constituting the KDEL receptor gene family, have been described. The protein encoded by this gene was the first member of the family to be identified, and it encodes a protein structurally and functionally similar to the yeast ERD2 gene product. [provided by RefSeq, Jul 2008]
Target ID |
GM-IP1041
|
Target Name |
KDELR1
|
Gene Group ldentifer (Target Gene ID in Homo
species)
|
10945
|
Gene ID |
100050944 (Equus caballus), 101088968 (Felis catus), 10945 (Homo sapiens), 361577 (Rattus norvegicus) 484406 (Canis lupus familiaris), 618184 (Bos taurus), 68137 (Mus musculus), 717928 (Macaca mulatta)
|
Target Alternative Names |
KDELR1,Kdelr1,ERD2,HDEL,PM23,ERD2.1,Erd2.1,8030486F04Rik,KDELR2
|
Uniprot Accession |
P24390,Q569A6,P33946,Q99JH8
|
Uniprot Entry Name |
|
Protein Sub-location |
Introcelluar Protein
|
Category |
|
Disease |
|
Disease from KEGG |
|
Gene Ensembl |
ENSG00000105438, ENSBTAG00000004463, ENSMUSG00000002778, ENSMMUG00000013072
|
Target Classification |
|
KDELR1 siRNA/miRNA/oligo for RNA interfence (RNAi)
Cat No. | Product Name | GeneID | Species | Grade | Detail |
---|
pGMoligo10945 | Pre-made Human KDELR1/ERD2/HDEL siRNA oligo Duplex | 10945 | Human | In-vitro grade; in-vivo grade | Detail |
pGMoligo361577 | Pre-made Rat Kdelr1 siRNA oligo Duplex | 361577 | Rat | In-vitro grade; in-vivo grade | Detail |
pGMoligo68137 | Pre-made Mouse Kdelr1/Erd2.1/8030486F04Rik siRNA oligo Duplex | 68137 | Mouse | In-vitro grade; in-vivo grade | Detail |
pGMoligo717928 | Pre-made Cynomolgus/Rhesus macaque KDELR1/KDELR2 siRNA oligo Duplex | 717928 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
pGMoligo101088968 | Pre-made Cat/Feline KDELR1 siRNA oligo Duplex | 101088968 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
pGMoligo484406 | Pre-made Dog/Canine KDELR1 siRNA oligo Duplex | 484406 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
pGMoligo618184 | Pre-made Bovines/Cattle KDELR1 siRNA oligo Duplex | 618184 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
pGMoligo100050944 | Pre-made Equine/Horse KDELR1 siRNA oligo Duplex | 100050944 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
KDELR1 antibody/GMab
Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
---|
GM-Tg-hg-IP1041-Ab | Human | Anti-Human KDELR1 monoclonal antibody | mab | | Detail |
GM-Tg-rg-IP1041-Ab | Rat | Anti-Rat KDELR1 monoclonal antibody | mab | | Detail |
GM-Tg-mg-IP1041-Ab | Mouse | Anti-Mouse KDELR1 monoclonal antibody | mab | | Detail |
GM-Tg-cynog-IP1041-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque KDELR1 monoclonal antibody | mab | | Detail |
GM-Tg-felg-IP1041-Ab | Cat/Feline | Anti-Cat/Feline KDELR1 monoclonal antibody | mab | | Detail |
GM-Tg-cang-IP1041-Ab | Dog/Canine | Anti-Dog/Canine KDELR1 monoclonal antibody | mab | | Detail |
GM-Tg-bovg-IP1041-Ab | Bovines/Cattle | Anti-Bovines/Cattle KDELR1 monoclonal antibody | mab | | Detail |
GM-Tg-equg-IP1041-Ab | Equine/Horse | Anti-Equine/Horse KDELR1 monoclonal antibody | mab | | Detail |
KDELR1 recombinant protein
Cat No. | Species | Antigen Name | Expression Platform | Detail |
---|
GM-Tg-hg-IP1041-Ag | Human | Human KDELR1 recombinant protein | Mammalian cell | Detail |
GM-Tg-rg-IP1041-Ag | Rat | Rat KDELR1 recombinant protein | Mammalian cell | Detail |
GM-Tg-mg-IP1041-Ag | Mouse | Mouse KDELR1 recombinant protein | Mammalian cell | Detail |
GM-Tg-cynog-IP1041-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque KDELR1 recombinant protein | Mammalian cell | Detail |
GM-Tg-felg-IP1041-Ag | Cat/Feline | Cat/Feline KDELR1 recombinant protein | Mammalian cell | Detail |
GM-Tg-cang-IP1041-Ag | Dog/Canine | Dog/Canine KDELR1 recombinant protein | Mammalian cell | Detail |
GM-Tg-bovg-IP1041-Ag | Bovines/Cattle | Bovines/Cattle KDELR1 recombinant protein | Mammalian cell | Detail |
GM-Tg-equg-IP1041-Ag | Equine/Horse | Equine/Horse KDELR1 recombinant protein | Mammalian cell | Detail |