Recombinant multi-species KDELR1 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine KDELR1 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
Retention of resident soluble proteins in the lumen of the endoplasmic reticulum (ER) is achieved in both yeast and animal cells by their continual retrieval from the cis-Golgi, or a pre-Golgi compartment. Sorting of these proteins is dependent on a C-terminal tetrapeptide signal, usually lys-asp-glu-leu (KDEL) in animal cells, and his-asp-glu-leu (HDEL) in S. cerevisiae. This process is mediated by a receptor that recognizes, and binds the tetrapeptide-containing protein, and returns it to the ER. In yeast, the sorting receptor encoded by a single gene, ERD2, which is a seven-transmembrane protein. Unlike yeast, several human homologs of the ERD2 gene, constituting the KDEL receptor gene family, have been described. The protein encoded by this gene was the first member of the family to be identified, and it encodes a protein structurally and functionally similar to the yeast ERD2 gene product. [provided by RefSeq, Jul 2008]
The Alternative Names of target: KDELR1,ER lumen protein-retaining receptor 1,KDEL endoplasmic reticulum protein retention receptor 1 (KDEL receptor 1), Putative MAPK-activating protein PM23,ERD2,HDEL,PM23,ERD2.1

Target products collectionGo to KDELR1 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

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Product information

Catalog No. Product Name Species Reactivity
GM-Tg-hg-IP1041-Ab-1/ GM-Tg-hg-IP1041-Ab-2 Human KDELR1 protein Human
GM-Tg-rg-IP1041-Ab-1/ GM-Tg-rg-IP1041-Ab-2 Rat KDELR1 protein Rat
GM-Tg-mg-IP1041-Ab-1/ GM-Tg-mg-IP1041-Ab-2 Mouse KDELR1 protein Mouse
GM-Tg-cynog-IP1041-Ab-1/ GM-Tg-cynog-IP1041-Ab-2 Cynomolgus/Rhesus macaque KDELR1 monoclonal antibody Cynomolgus/ Rhesus macaque
GM-Tg-felg-IP1041-Ab-1/ GM-Tg-felg-IP1041-Ab-2 Feline KDELR1 protein Feline
GM-Tg-cang-IP1041-Ab-1/ GM-Tg-cang-IP1041-Ab-2 Canine KDELR1 protein Canine
GM-Tg-bovg-IP1041-Ab-1/ GM-Tg-bovg-IP1041-Ab-2 Bovine KDELR1 protein Bovine
GM-Tg-equg-IP1041-Ab-1/ GM-Tg-equg-IP1041-Ab-2 Equine KDELR1 protein Equine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No. GM-Tg-hg-IP1041-Ab-1/ GM-Tg-hg-IP1041-Ab-2; GM-Tg-rg-IP1041-Ab-1/ GM-Tg-rg-IP1041-Ab-2;
GM-Tg-mg-IP1041-Ab-1/ GM-Tg-mg-IP1041-Ab-2; GM-Tg-cynog-IP1041-Ab-1/ GM-Tg-cynog-IP1041-Ab-2;
GM-Tg-felg-IP1041-Ab-1/ GM-Tg-felg-IP1041-Ab-2; GM-Tg-cang-IP1041-Ab-1/ GM-Tg-cang-IP1041-Ab-2;
GM-Tg-bovg-IP1041-Ab-1/ GM-Tg-bovg-IP1041-Ab-2; GM-Tg-equg-IP1041-Ab-1/ GM-Tg-equg-IP1041-Ab-2
Products Name KDELR1 protein
Species Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine
Target Name KDELR1
Protein Sub-location Introcelluar Protein
Isotypes Recombinant protein
Expression platform Mammalian cell
Bioactivity validation Affintiy&bioactivity validated by ELISA, cell culture validated.
Tag His
Products description Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine KDELR1 protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic).
Purity Purity: ≥95% (SDS-PAGE)
Application In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference






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