Explore HR gene products and cross-species
research data at TarMart platform. Discover comprehensive
biological information, expression tools, and therapeutic
insights for Homo sapiens (human), Cynomolgus monkeys, rodents
(mouse/rat), canines, felines, bovines, and equines. Your
premier destination for multi-species gene research solutions
Target
sublocation: Introcelluar Protein.
This gene encodes a protein that is involved in hair growth. This protein functions as a transcriptional corepressor of multiple nuclear receptors, including thyroid hormone receptor, the retinoic acid receptor-related orphan receptors and the vitamin D receptors, and it interacts with histone deacetylases. The translation of this protein is modulated by a regulatory open reading frame (ORF) that exists upstream of the primary ORF. Mutations in this upstream ORF cause Marie Unna hereditary hypotrichosis (MUHH), an autosomal dominant form of genetic hair loss. Mutations in this gene also cause autosomal recessive congenital alopecia and atrichia with papular lesions, other diseases resulting in hair loss. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2014]
| Target ID |
GM-IP10312
|
| Target Name |
HR
|
Gene Group ldentifer (Target Gene ID in Homo
species)
|
55806
|
| Gene ID |
100053727 (Equus caballus), 101090097 (Felis catus), 15460 (Mus musculus), 486130 (Canis lupus familiaris) 55806 (Homo sapiens), 574164 (Macaca mulatta), 60563 (Rattus norvegicus), 785815 (Bos taurus)
|
| Target Alternative Names |
ALUNC,AU,HR,HSA277165,HYPT4,Hr,Lysine-specific demethylase hairless,MUHH,MUHH1,[histone H3]-dimethyl-L-lysine(9) demethylase hairless,bldy,hr,rh-bmh
|
| Uniprot Accession |
Q61645,O43593,P97609
|
| Protein Sub-location |
Introcelluar Protein
|
| Category |
Life Science Target
|
| Gene Ensembl |
ENSECAG00000010917, ENSMUSG00000022096, ENSCAFG00845026480, ENSG00000168453, ENSMMUG00000013022, ENSBTAG00000012036
|
HR siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo55806 | Pre-made Human HR/AU/MUHH siRNA oligo Duplex | 55806 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo60563 | Pre-made Rat Hr siRNA oligo Duplex | 60563 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo15460 | Pre-made Mouse Hr/hr/bldy siRNA oligo Duplex | 15460 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo574164 | Pre-made Cynomolgus/Rhesus macaque HR siRNA oligo Duplex | 574164 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101090097 | Pre-made Cat/Feline HR siRNA oligo Duplex | 101090097 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo486130 | Pre-made Dog/Canine HR siRNA oligo Duplex | 486130 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo785815 | Pre-made Bovines/Cattle HR siRNA oligo Duplex | 785815 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100053727 | Pre-made Equine/Horse HR siRNA oligo Duplex | 100053727 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
HR antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-IP10312-Ab | Human | Anti-Human HR monoclonal antibody | mab | | Detail |
| GM-Tg-rg-IP10312-Ab | Rat | Anti-Rat HR monoclonal antibody | mab | | Detail |
| GM-Tg-mg-IP10312-Ab | Mouse | Anti-Mouse HR monoclonal antibody | mab | | Detail |
| GM-Tg-cynog-IP10312-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque HR monoclonal antibody | mab | | Detail |
| GM-Tg-felg-IP10312-Ab | Cat/Feline | Anti-Cat/Feline HR monoclonal antibody | mab | | Detail |
| GM-Tg-cang-IP10312-Ab | Dog/Canine | Anti-Dog/Canine HR monoclonal antibody | mab | | Detail |
| GM-Tg-bovg-IP10312-Ab | Bovines/Cattle | Anti-Bovines/Cattle HR monoclonal antibody | mab | | Detail |
| GM-Tg-equg-IP10312-Ab | Equine/Horse | Anti-Equine/Horse HR monoclonal antibody | mab | | Detail |
HR recombinant protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-IP10312-Ag | Human | Human HR recombinant protein | Mammalian cell | Detail |
| GM-Tg-rg-IP10312-Ag | Rat | Rat HR recombinant protein | Mammalian cell | Detail |
| GM-Tg-mg-IP10312-Ag | Mouse | Mouse HR recombinant protein | Mammalian cell | Detail |
| GM-Tg-cynog-IP10312-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque HR recombinant protein | Mammalian cell | Detail |
| GM-Tg-felg-IP10312-Ag | Cat/Feline | Cat/Feline HR recombinant protein | Mammalian cell | Detail |
| GM-Tg-cang-IP10312-Ag | Dog/Canine | Dog/Canine HR recombinant protein | Mammalian cell | Detail |
| GM-Tg-bovg-IP10312-Ag | Bovines/Cattle | Bovines/Cattle HR recombinant protein | Mammalian cell | Detail |
| GM-Tg-equg-IP10312-Ag | Equine/Horse | Equine/Horse HR recombinant protein | Mammalian cell | Detail |