Explore HTRA2 gene products and cross-species
research data at TarMart platform. Discover comprehensive
biological information, expression tools, and therapeutic
insights for Homo sapiens (human), Cynomolgus monkeys, rodents
(mouse/rat), canines, felines, bovines, and equines. Your
premier destination for multi-species gene research solutions
Target
sublocation: Introcelluar Protein.
This gene encodes a serine protease. The protein has been localized in the endoplasmic reticulum and interacts with an alternatively spliced form of mitogen-activated protein kinase 14. The protein has also been localized to the mitochondria with release to the cytosol following apoptotic stimulus. The protein is thought to induce apoptosis by binding the apoptosis inhibitory protein baculoviral IAP repeat-containing 4. Nuclear localization of this protein has also been observed. Alternate splicing of this gene results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Mar 2016]
| Target ID |
GM-IP0992
|
| Target Name |
HTRA2
|
Gene Group ldentifer (Target Gene ID in Homo
species)
|
27429
|
| Gene ID |
100053688 (Equus caballus), 27429 (Homo sapiens), 297376 (Rattus norvegicus), 475782 (Canis lupus familiaris) 523039 (Bos taurus), 64704 (Mus musculus), 709938 (Macaca mulatta), 768259 (Felis catus)
|
| Target Alternative Names |
HTRA2,High temperature requirement protein A2 (HtrA2),Htra2,MGCA8,OMI,Omi,Omi stress-regulated endoprotease,PARK13,PRSS25,Prss25,Serine protease 25,Serine protease HTRA2,Serine proteinase OMI,mitochondrial,mnd2
|
| Uniprot Accession |
O43464,A0JNK3,Q9JIY5
|
| Protein Sub-location |
Introcelluar Protein
|
| Disease |
cancer
|
| Disease from KEGG |
Apoptosis, Apoptosis - multiple species
|
| Gene Ensembl |
ENSECAG00000000517, ENSG00000115317, ENSCAFG00845018463, ENSBTAG00000020124, ENSMUSG00000068329, ENSMMUG00000002136
|
Pre-made viral vector of HTRA2 cDNA Clones/ORF Plasmid
HTRA2 siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo27429 | Pre-made Human HTRA2/OMI/MGCA8 siRNA oligo Duplex | 27429 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo297376 | Pre-made Rat Htra2/Prss25 siRNA oligo Duplex | 297376 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo64704 | Pre-made Mouse Htra2/Omi/mnd2 siRNA oligo Duplex | 64704 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo709938 | Pre-made Cynomolgus/Rhesus macaque HTRA2 siRNA oligo Duplex | 709938 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo768259 | Pre-made Cat/Feline HTRA2/PRSS25 siRNA oligo Duplex | 768259 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo475782 | Pre-made Dog/Canine HTRA2 siRNA oligo Duplex | 475782 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo523039 | Pre-made Bovines/Cattle HTRA2 siRNA oligo Duplex | 523039 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100053688 | Pre-made Equine/Horse HTRA2 siRNA oligo Duplex | 100053688 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
HTRA2 antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-IP0992-Ab | Human | Anti-Human HTRA2 monoclonal antibody | mab | | Detail |
| GM-Tg-rg-IP0992-Ab | Rat | Anti-Rat HTRA2 monoclonal antibody | mab | | Detail |
| GM-Tg-mg-IP0992-Ab | Mouse | Anti-Mouse HTRA2 monoclonal antibody | mab | | Detail |
| GM-Tg-cynog-IP0992-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque HTRA2 monoclonal antibody | mab | | Detail |
| GM-Tg-felg-IP0992-Ab | Cat/Feline | Anti-Cat/Feline HTRA2 monoclonal antibody | mab | | Detail |
| GM-Tg-cang-IP0992-Ab | Dog/Canine | Anti-Dog/Canine HTRA2 monoclonal antibody | mab | | Detail |
| GM-Tg-bovg-IP0992-Ab | Bovines/Cattle | Anti-Bovines/Cattle HTRA2 monoclonal antibody | mab | | Detail |
| GM-Tg-equg-IP0992-Ab | Equine/Horse | Anti-Equine/Horse HTRA2 monoclonal antibody | mab | | Detail |
HTRA2 recombinant protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-IP0992-Ag | Human | Human HTRA2 recombinant protein | Mammalian cell | Detail |
| GM-Tg-rg-IP0992-Ag | Rat | Rat HTRA2 recombinant protein | Mammalian cell | Detail |
| GM-Tg-mg-IP0992-Ag | Mouse | Mouse HTRA2 recombinant protein | Mammalian cell | Detail |
| GM-Tg-cynog-IP0992-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque HTRA2 recombinant protein | Mammalian cell | Detail |
| GM-Tg-felg-IP0992-Ag | Cat/Feline | Cat/Feline HTRA2 recombinant protein | Mammalian cell | Detail |
| GM-Tg-cang-IP0992-Ag | Dog/Canine | Dog/Canine HTRA2 recombinant protein | Mammalian cell | Detail |
| GM-Tg-bovg-IP0992-Ag | Bovines/Cattle | Bovines/Cattle HTRA2 recombinant protein | Mammalian cell | Detail |
| GM-Tg-equg-IP0992-Ag | Equine/Horse | Equine/Horse HTRA2 recombinant protein | Mammalian cell | Detail |