HLA-DMA Target & Gene Products-cDNA ORF clones/siRNA/antibody/protein

Explore HLA-DMA gene products and cross-species research data at TarMart platform. Discover comprehensive biological information, expression tools, and therapeutic insights for Homo sapiens (human), Cynomolgus monkeys, rodents (mouse/rat), canines, felines, bovines, and equines. Your premier destination for multi-species gene research solutions
Target sublocation: Introcelluar Protein.
HLA-DMA belongs to the HLA class II alpha chain paralogues. This class II molecule is a heterodimer consisting of an alpha (DMA) and a beta chain (DMB), both anchored in the membrane. It is located in intracellular vesicles. DM plays a central role in the peptide loading of MHC class II molecules by helping to release the CLIP molecule from the peptide binding site. Class II molecules are expressed in antigen presenting cells (APC: B lymphocytes, dendritic cells, macrophages). The alpha chain is approximately 33-35 kDa and its gene contains 5 exons. Exon one encodes the leader peptide, exons 2 and 3 encode the two extracellular domains, exon 4 encodes the transmembrane domain and the cytoplasmic tail. [provided by RefSeq, Jul 2008]

Target ID GM-IP0970
Target Name HLA-DMA
Gene Group ldentifer
(Target Gene ID in Homo species)
3108
Gene ID 100061035 (Equus caballus), 111560443 (Felis catus), 14998 (Mus musculus), 282490 (Bos taurus)
294274 (Rattus norvegicus), 3108 (Homo sapiens), 481732 (Canis lupus familiaris), 717870 (Macaca mulatta)
Target Alternative Names LOC100061035,LOC111560443,H2-DMa,BOLA-DMA,RT1-DMa,HLA-DMA,DLA-DMA,MAMU-DMA,H-2Ma,H2-Ma,DMA,DMA1,RT1.Ma,RT1.DMa,HLADM,RING6,D6S222E
Uniprot Accession P28078,P28067
Uniprot Entry Name
Protein Sub-location Introcelluar Protein
Category
Disease
Disease from KEGG Phagosome, Cell adhesion molecules, Antigen processing and presentation, Hematopoietic cell lineage, Th1 and Th2 cell differentiation, Th17 cell differentiation, Intestinal immune network for IgA production, Type I diabetes mellitus, Leishmaniasis, Toxoplasmosis, Staphylococcus aureus infection, Tuberculosis, Influenza A, Human T-cell leukemia virus 1 infection, Epstein-Barr virus infection, Asthma, Autoimmune thyroid disease, Inflammatory bowel disease, Rheumatoid arthritis, Allograft rejection, Graft-versus-host disease, Viral myocarditis
Gene Ensembl ENSECAG00000003669, ENSMUSG00000037649, ENSBTAG00000015730, ENSG00000204257, ENSCAFG00845018613, ENSMMUG00000022626
Target Classification


Pre-made viral vector of HLA-DMA cDNA Clones/ORF Plasmid

Cat No.Product NameNMIDGeneIDSpeciesTypeMarkerFusion TagPromoterDetail
pGMLP002653Human HLA-DMA/D6S222E/DMA Lentivirus plasmidNM_0061203108HumanLentivirus plasmidZsGreen3xflag (C-Terminal)CMVDetail
vGMLP002653Human HLA-DMA/D6S222E/DMA Lentivirus particleNM_0061203108HumanLentivirus particleZsGreen3xflag (C-Terminal)CMVDetail


HLA-DMA siRNA/miRNA/oligo for RNA interfence (RNAi)

Cat No.Product NameGeneIDSpeciesGradeDetail
pGMoligo3108Pre-made Human HLA-DMA/DMA/HLADM siRNA oligo Duplex3108HumanIn-vitro grade; in-vivo gradeDetail
pGMoligo294274Pre-made Rat RT1-DMa/DMA1/RT1.Ma siRNA oligo Duplex294274RatIn-vitro grade; in-vivo gradeDetail
pGMoligo14998Pre-made Mouse H2-DMa/H-2Ma/H2-Ma siRNA oligo Duplex14998MouseIn-vitro grade; in-vivo gradeDetail
pGMoligo717870Pre-made Cynomolgus/Rhesus macaque MAMU-DMA siRNA oligo Duplex717870Cynomolgus/Rhesus macaqueIn-vitro grade; in-vivo gradeDetail
pGMoligo111560443Pre-made Cat/Feline LOC111560443 siRNA oligo Duplex111560443Cat/FelineIn-vitro grade; in-vivo gradeDetail
pGMoligo481732Pre-made Dog/Canine DLA-DMA siRNA oligo Duplex481732Dog/CanineIn-vitro grade; in-vivo gradeDetail
pGMoligo282490Pre-made Bovines/Cattle BOLA-DMA/DMA siRNA oligo Duplex282490Bovines/CattleIn-vitro grade; in-vivo gradeDetail
pGMoligo100061035Pre-made Equine/Horse LOC100061035 siRNA oligo Duplex100061035Equine/HorseIn-vitro grade; in-vivo gradeDetail


HLA-DMA antibody/GMab

Cat No.SpeciesAntibody NameFormatClassified by tagDetail
GM-Tg-hg-IP0970-AbHumanAnti-Human HLA-DMA monoclonal antibodymabDetail
GM-Tg-rg-IP0970-AbRatAnti-Rat HLA-DMA monoclonal antibodymabDetail
GM-Tg-mg-IP0970-AbMouseAnti-Mouse HLA-DMA monoclonal antibodymabDetail
GM-Tg-cynog-IP0970-AbCynomolgus/Rhesus macaqueAnti-Cynomolgus/Rhesus macaque HLA-DMA monoclonal antibodymabDetail
GM-Tg-felg-IP0970-AbCat/FelineAnti-Cat/Feline HLA-DMA monoclonal antibodymabDetail
GM-Tg-cang-IP0970-AbDog/CanineAnti-Dog/Canine HLA-DMA monoclonal antibodymabDetail
GM-Tg-bovg-IP0970-AbBovines/CattleAnti-Bovines/Cattle HLA-DMA monoclonal antibodymabDetail
GM-Tg-equg-IP0970-AbEquine/HorseAnti-Equine/Horse HLA-DMA monoclonal antibodymabDetail


HLA-DMA recombinant protein

Cat No.SpeciesAntigen NameExpression PlatformDetail
GM-Tg-hg-IP0970-AgHumanHuman HLA-DMA recombinant proteinMammalian cellDetail
GM-Tg-rg-IP0970-AgRatRat HLA-DMA recombinant proteinMammalian cellDetail
GM-Tg-mg-IP0970-AgMouseMouse HLA-DMA recombinant proteinMammalian cellDetail
GM-Tg-cynog-IP0970-AgCynomolgus/Rhesus macaqueCynomolgus/Rhesus macaque HLA-DMA recombinant proteinMammalian cellDetail
GM-Tg-felg-IP0970-AgCat/FelineCat/Feline HLA-DMA recombinant proteinMammalian cellDetail
GM-Tg-cang-IP0970-AgDog/CanineDog/Canine HLA-DMA recombinant proteinMammalian cellDetail
GM-Tg-bovg-IP0970-AgBovines/CattleBovines/Cattle HLA-DMA recombinant proteinMammalian cellDetail
GM-Tg-equg-IP0970-AgEquine/HorseEquine/Horse HLA-DMA recombinant proteinMammalian cellDetail