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insights for Homo sapiens (human), Cynomolgus monkeys, rodents
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Target
sublocation: Introcelluar Protein.
This gene encodes a transmembrane protein belonging to a family of proteins containing TLC domains, which are postulated to function in lipid synthesis, transport, or sensing. The protein localizes to the endoplasmic reticulum (ER), and may recycle between the ER and ER-Golgi intermediate compartment. Mutations in this gene are associated with a disorder characterized by progressive epilepsy with cognitive disabilities (EPMR), which is a subtype of neuronal ceroid lipofuscinoses (NCL). Patients with mutations in this gene have altered levels of sphingolipid and phospholipids in the brain. [provided by RefSeq, Jul 2017]
| Target ID |
GM-IP0563
|
| Target Name |
CLN8
|
Gene Group ldentifer (Target Gene ID in Homo
species)
|
2055
|
| Gene ID |
100065372 (Equus caballus), 101100714 (Felis catus), 2055 (Homo sapiens), 26889 (Mus musculus) 306619 (Rattus norvegicus), 488558 (Canis lupus familiaris), 530874 (Bos taurus), 716441 (Macaca mulatta)
|
| Target Alternative Names |
C8orf61,CLN8,Cln8,EPMR,Protein CLN8,TLCD6,Tlcd6,mnd
|
| Uniprot Accession |
Q9UBY8,Q9QUK3,Q6AYM9,Q5JZQ7
|
| Protein Sub-location |
Introcelluar Protein
|
| Gene Ensembl |
ENSG00000182372, ENSMUSG00000026317, ENSCAFG00845019093, ENSMMUG00000009470
|
Pre-made viral vector of CLN8 cDNA Clones/ORF Plasmid
CLN8 siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo2055 | Pre-made Human CLN8/EPMR/TLCD6 siRNA oligo Duplex | 2055 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo306619 | Pre-made Rat Cln8 siRNA oligo Duplex | 306619 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo26889 | Pre-made Mouse Cln8/mnd/Tlcd6 siRNA oligo Duplex | 26889 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo716441 | Pre-made Cynomolgus/Rhesus macaque CLN8 siRNA oligo Duplex | 716441 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101100714 | Pre-made Cat/Feline CLN8 siRNA oligo Duplex | 101100714 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo488558 | Pre-made Dog/Canine CLN8 siRNA oligo Duplex | 488558 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo530874 | Pre-made Bovines/Cattle CLN8 siRNA oligo Duplex | 530874 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100065372 | Pre-made Equine/Horse CLN8 siRNA oligo Duplex | 100065372 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
CLN8 antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-IP0563-Ab | Human | Anti-Human CLN8 monoclonal antibody | mab | | Detail |
| GM-Tg-rg-IP0563-Ab | Rat | Anti-Rat CLN8 monoclonal antibody | mab | | Detail |
| GM-Tg-mg-IP0563-Ab | Mouse | Anti-Mouse CLN8 monoclonal antibody | mab | | Detail |
| GM-Tg-cynog-IP0563-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque CLN8 monoclonal antibody | mab | | Detail |
| GM-Tg-felg-IP0563-Ab | Cat/Feline | Anti-Cat/Feline CLN8 monoclonal antibody | mab | | Detail |
| GM-Tg-cang-IP0563-Ab | Dog/Canine | Anti-Dog/Canine CLN8 monoclonal antibody | mab | | Detail |
| GM-Tg-bovg-IP0563-Ab | Bovines/Cattle | Anti-Bovines/Cattle CLN8 monoclonal antibody | mab | | Detail |
| GM-Tg-equg-IP0563-Ab | Equine/Horse | Anti-Equine/Horse CLN8 monoclonal antibody | mab | | Detail |
CLN8 recombinant protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-IP0563-Ag | Human | Human CLN8 recombinant protein | Mammalian cell | Detail |
| GM-Tg-rg-IP0563-Ag | Rat | Rat CLN8 recombinant protein | Mammalian cell | Detail |
| GM-Tg-mg-IP0563-Ag | Mouse | Mouse CLN8 recombinant protein | Mammalian cell | Detail |
| GM-Tg-cynog-IP0563-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque CLN8 recombinant protein | Mammalian cell | Detail |
| GM-Tg-felg-IP0563-Ag | Cat/Feline | Cat/Feline CLN8 recombinant protein | Mammalian cell | Detail |
| GM-Tg-cang-IP0563-Ag | Dog/Canine | Dog/Canine CLN8 recombinant protein | Mammalian cell | Detail |
| GM-Tg-bovg-IP0563-Ag | Bovines/Cattle | Bovines/Cattle CLN8 recombinant protein | Mammalian cell | Detail |
| GM-Tg-equg-IP0563-Ag | Equine/Horse | Equine/Horse CLN8 recombinant protein | Mammalian cell | Detail |