IDH2 Target & Gene Products-cDNA ORF clones/siRNA/antibody/protein

Explore IDH2 gene products and cross-species research data at TarMart platform. Discover comprehensive biological information, expression tools, and therapeutic insights for Homo sapiens (human), Cynomolgus monkeys, rodents (mouse/rat), canines, felines, bovines, and equines. Your premier destination for multi-species gene research solutions
Target sublocation: Introcelluar Protein.
Isocitrate dehydrogenases catalyze the oxidative decarboxylation of isocitrate to 2-oxoglutarate. These enzymes belong to two distinct subclasses, one of which utilizes NAD(+) as the electron acceptor and the other NADP(+). Five isocitrate dehydrogenases have been reported: three NAD(+)-dependent isocitrate dehydrogenases, which localize to the mitochondrial matrix, and two NADP(+)-dependent isocitrate dehydrogenases, one of which is mitochondrial and the other predominantly cytosolic. Each NADP(+)-dependent isozyme is a homodimer. The protein encoded by this gene is the NADP(+)-dependent isocitrate dehydrogenase found in the mitochondria. It plays a role in intermediary metabolism and energy production. This protein may tightly associate or interact with the pyruvate dehydrogenase complex. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2014]

Target ID GM-IP0248
Target Name IDH2
Gene Group ldentifer
(Target Gene ID in Homo species)
3418
Gene ID 100069086 (Equus caballus), 101082315 (Felis catus), 269951 (Mus musculus), 327669 (Bos taurus)
3418 (Homo sapiens), 361596 (Rattus norvegicus), 479043 (Canis lupus familiaris), 701480 (Macaca mulatta)
Target Alternative Names D2HGA2,E430004F23,ICD-M,IDH,IDH-2,IDH2,IDHM,IDP,IDPM,IDPm,Idh-2,Idh2,Isocitrate dehydrogenase [NADP],NADP(+)-specific ICDH,Oxalosuccinate decarboxylase,mNADP-IDH,mitochondrial
Uniprot Accession P54071,Q04467,P48735,P56574
Protein Sub-location Introcelluar Protein
Category Therapeutics Target
Disease cancer
Disease from KEGG Metabolic pathways, Central carbon metabolism in cancer
Gene Ensembl ENSECAG00000007105, ENSMUSG00000030541, ENSBTAG00000014093, ENSG00000182054, ENSCAFG00845000909, ENSMMUG00000014833
Target Classification Tumor-associated antigen (TAA)


Pre-made viral vector of IDH2 cDNA Clones/ORF Plasmid

Cat No.Product NameNMIDGeneIDSpeciesTypeMarkerFusion TagPromoterDetail
pGMLV001151Human IDH2/D2HGA2/ICD-M Lentivirus plasmidNM_0021683418HumanLentivirus plasmidZsGreen3xflag (C-Terminal)CMVDetail
pGMLV001472Human IDH2/D2HGA2/ICD-M Lentivirus plasmidNM_002168.43418HumanLentivirus plasmidZsGreen3xflag (C-Terminal)CMVDetail
pGMPC000344Human IDH2/D2HGA2/ICD-M Mammalian (Non-Viral Vector) plasmidNM_0021683418HumanMammalian (Non-Viral Vector) plasmidZsGreen3xflag (C-Terminal)CMVDetail
vGMLV001151Human IDH2/D2HGA2/ICD-M Lentivirus particleNM_0021683418HumanLentivirus particleZsGreen3xflag (C-Terminal)CMVDetail
vGMLV001472Human IDH2/D2HGA2/ICD-M Lentivirus particleNM_002168.43418HumanLentivirus particleZsGreen3xflag (C-Terminal)CMVDetail
pGMLPm002194Mouse Idh2/E430004F23/Idh-2 Lentivirus plasmidNM_173011269951MouseLentivirus plasmidZsGreen3xflag (C-Terminal)CMVDetail
vGMLPm002194Mouse Idh2/E430004F23/Idh-2 Lentivirus particleNM_173011269951MouseLentivirus particleZsGreen3xflag (C-Terminal)CMVDetail


IDH2 siRNA/miRNA/oligo for RNA interfence (RNAi)

Cat No.Product NameGeneIDSpeciesGradeDetail
pGMoligo3418Pre-made Human IDH2/IDH/IDP siRNA oligo Duplex3418HumanIn-vitro grade; in-vivo gradeDetail
pGMoligo361596Pre-made Rat Idh2 siRNA oligo Duplex361596RatIn-vitro grade; in-vivo gradeDetail
pGMoligo269951Pre-made Mouse Idh2/IDPm/Idh-2 siRNA oligo Duplex269951MouseIn-vitro grade; in-vivo gradeDetail
pGMoligo701480Pre-made Cynomolgus/Rhesus macaque IDH2 siRNA oligo Duplex701480Cynomolgus/Rhesus macaqueIn-vitro grade; in-vivo gradeDetail
pGMoligo101082315Pre-made Cat/Feline IDH2 siRNA oligo Duplex101082315Cat/FelineIn-vitro grade; in-vivo gradeDetail
pGMoligo479043Pre-made Dog/Canine IDH2 siRNA oligo Duplex479043Dog/CanineIn-vitro grade; in-vivo gradeDetail
pGMoligo327669Pre-made Bovines/Cattle IDH2 siRNA oligo Duplex327669Bovines/CattleIn-vitro grade; in-vivo gradeDetail
pGMoligo100069086Pre-made Equine/Horse IDH2 siRNA oligo Duplex100069086Equine/HorseIn-vitro grade; in-vivo gradeDetail


IDH2 antibody/GMab

Cat No.SpeciesAntibody NameFormatClassified by tagDetail
GM-Tg-hg-IP0248-AbHumanAnti-Human IDH2 monoclonal antibodymabTherapeutics Target antibodyDetail
GM-Tg-rg-IP0248-AbRatAnti-Rat IDH2 monoclonal antibodymabTherapeutics Target antibodyDetail
GM-Tg-mg-IP0248-AbMouseAnti-Mouse IDH2 monoclonal antibodymabTherapeutics Target antibodyDetail
GM-Tg-cynog-IP0248-AbCynomolgus/Rhesus macaqueAnti-Cynomolgus/Rhesus macaque IDH2 monoclonal antibodymabTherapeutics Target antibodyDetail
GM-Tg-felg-IP0248-AbCat/FelineAnti-Cat/Feline IDH2 monoclonal antibodymabTherapeutics Target antibodyDetail
GM-Tg-cang-IP0248-AbDog/CanineAnti-Dog/Canine IDH2 monoclonal antibodymabTherapeutics Target antibodyDetail
GM-Tg-bovg-IP0248-AbBovines/CattleAnti-Bovines/Cattle IDH2 monoclonal antibodymabTherapeutics Target antibodyDetail
GM-Tg-equg-IP0248-AbEquine/HorseAnti-Equine/Horse IDH2 monoclonal antibodymabTherapeutics Target antibodyDetail


IDH2 recombinant protein

Cat No.SpeciesAntigen NameExpression PlatformDetail
GM-Tg-hg-IP0248-AgHumanHuman IDH2 recombinant proteinMammalian cellDetail
GM-Tg-rg-IP0248-AgRatRat IDH2 recombinant proteinMammalian cellDetail
GM-Tg-mg-IP0248-AgMouseMouse IDH2 recombinant proteinMammalian cellDetail
GM-Tg-cynog-IP0248-AgCynomolgus/Rhesus macaqueCynomolgus/Rhesus macaque IDH2 recombinant proteinMammalian cellDetail
GM-Tg-felg-IP0248-AgCat/FelineCat/Feline IDH2 recombinant proteinMammalian cellDetail
GM-Tg-cang-IP0248-AgDog/CanineDog/Canine IDH2 recombinant proteinMammalian cellDetail
GM-Tg-bovg-IP0248-AgBovines/CattleBovines/Cattle IDH2 recombinant proteinMammalian cellDetail
GM-Tg-equg-IP0248-AgEquine/HorseEquine/Horse IDH2 recombinant proteinMammalian cellDetail