Explore CAMLG gene products and cross-species
research data at TarMart platform. Discover comprehensive
biological information, expression tools, and therapeutic
insights for Homo sapiens (human), Cynomolgus monkeys, rodents
(mouse/rat), canines, felines, bovines, and equines. Your
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Target
sublocation: Introcelluar Protein.
The immunosuppressant drug cyclosporin A blocks a calcium-dependent signal from the T-cell receptor (TCR) that normally leads to T-cell activation. When bound to cyclophilin B, cyclosporin A binds and inactivates the key signaling intermediate calcineurin. The protein encoded by this gene functions similarly to cyclosporin A, binding to cyclophilin B and acting downstream of the TCR and upstream of calcineurin by causing an influx of calcium. This integral membrane protein appears to be a new participant in the calcium signal transduction pathway, implicating cyclophilin B in calcium signaling, even in the absence of cyclosporin. [provided by RefSeq, Jul 2008]
| Target ID |
GM-IP0245
|
| Target Name |
CAMLG
|
Gene Group ldentifer
（Target Gene ID in Homo
species)
|
819
|
| Gene ID |
100062812 (Equus caballus), 101100691 (Felis catus), 12328 (Mus musculus), 474684 (Canis lupus familiaris)
615658 (Bos taurus), 711188 (Macaca mulatta), 81715 (Rattus norvegicus), 819 (Homo sapiens)
|
| Target Alternative Names |
CAMLG,Caml,Camlg,CAML,GET2,CDG2Z
|
| Uniprot Accession |
P49070,Q6DGG9,P49069
|
| Uniprot Entry Name |
|
| Protein Sub-location |
Introcelluar Protein
|
| Category |
Therapeutics Target
|
| Disease |
|
| Disease from KEGG |
|
| Gene Ensembl |
ENSECAG00000001757, ENSMUSG00000021501, ENSCAFG00845013583, ENSBTAG00000021519, ENSMMUG00000056880, ENSG00000164615
|
| Target Classification |
|
CAMLG siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo819 | Pre-made Human CAMLG/CAML/GET2 siRNA oligo Duplex | 819 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo81715 | Pre-made Rat Camlg/Caml siRNA oligo Duplex | 81715 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo12328 | Pre-made Mouse Caml/Camlg siRNA oligo Duplex | 12328 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo711188 | Pre-made Cynomolgus/Rhesus macaque CAMLG siRNA oligo Duplex | 711188 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101100691 | Pre-made Cat/Feline CAMLG siRNA oligo Duplex | 101100691 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo474684 | Pre-made Dog/Canine CAMLG siRNA oligo Duplex | 474684 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo615658 | Pre-made Bovines/Cattle CAMLG siRNA oligo Duplex | 615658 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100062812 | Pre-made Equine/Horse CAMLG siRNA oligo Duplex | 100062812 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
CAMLG antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-IP0245-Ab | Human | Anti-Human CAMLG monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-rg-IP0245-Ab | Rat | Anti-Rat CAMLG monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-mg-IP0245-Ab | Mouse | Anti-Mouse CAMLG monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-cynog-IP0245-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque CAMLG monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-felg-IP0245-Ab | Cat/Feline | Anti-Cat/Feline CAMLG monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-cang-IP0245-Ab | Dog/Canine | Anti-Dog/Canine CAMLG monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-bovg-IP0245-Ab | Bovines/Cattle | Anti-Bovines/Cattle CAMLG monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-equg-IP0245-Ab | Equine/Horse | Anti-Equine/Horse CAMLG monoclonal antibody | mab | Therapeutics Target antibody | Detail |
CAMLG recombinant protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-IP0245-Ag | Human | Human CAMLG recombinant protein | Mammalian cell | Detail |
| GM-Tg-rg-IP0245-Ag | Rat | Rat CAMLG recombinant protein | Mammalian cell | Detail |
| GM-Tg-mg-IP0245-Ag | Mouse | Mouse CAMLG recombinant protein | Mammalian cell | Detail |
| GM-Tg-cynog-IP0245-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque CAMLG recombinant protein | Mammalian cell | Detail |
| GM-Tg-felg-IP0245-Ag | Cat/Feline | Cat/Feline CAMLG recombinant protein | Mammalian cell | Detail |
| GM-Tg-cang-IP0245-Ag | Dog/Canine | Dog/Canine CAMLG recombinant protein | Mammalian cell | Detail |
| GM-Tg-bovg-IP0245-Ag | Bovines/Cattle | Bovines/Cattle CAMLG recombinant protein | Mammalian cell | Detail |
| GM-Tg-equg-IP0245-Ag | Equine/Horse | Equine/Horse CAMLG recombinant protein | Mammalian cell | Detail |
