Recombinant multi-species CAMLG protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine CAMLG protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
The immunosuppressant drug cyclosporin A blocks a calcium-dependent signal from the T-cell receptor (TCR) that normally leads to T-cell activation. When bound to cyclophilin B, cyclosporin A binds and inactivates the key signaling intermediate calcineurin. The protein encoded by this gene functions similarly to cyclosporin A, binding to cyclophilin B and acting downstream of the TCR and upstream of calcineurin by causing an influx of calcium. This integral membrane protein appears to be a new participant in the calcium signal transduction pathway, implicating cyclophilin B in calcium signaling, even in the absence of cyclosporin. [provided by RefSeq, Jul 2008]
The Alternative Names of target: CAMLG,Guided entry of tail-anchored proteins factor CAMLG,Calcium signal-modulating cyclophilin ligand,CAML,GET2,CDG2Z

Target products collectionGo to CAMLG products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

pdfMSDSpdfCOApdfDatasheet

Product information

Catalog No. Product Name Species Reactivity
GM-Tg-hg-IP0245-Ab-1/ GM-Tg-hg-IP0245-Ab-2 Human CAMLG protein Human
GM-Tg-rg-IP0245-Ab-1/ GM-Tg-rg-IP0245-Ab-2 Rat CAMLG protein Rat
GM-Tg-mg-IP0245-Ab-1/ GM-Tg-mg-IP0245-Ab-2 Mouse CAMLG protein Mouse
GM-Tg-cynog-IP0245-Ab-1/ GM-Tg-cynog-IP0245-Ab-2 Cynomolgus/Rhesus macaque CAMLG monoclonal antibody Cynomolgus/ Rhesus macaque
GM-Tg-felg-IP0245-Ab-1/ GM-Tg-felg-IP0245-Ab-2 Feline CAMLG protein Feline
GM-Tg-cang-IP0245-Ab-1/ GM-Tg-cang-IP0245-Ab-2 Canine CAMLG protein Canine
GM-Tg-bovg-IP0245-Ab-1/ GM-Tg-bovg-IP0245-Ab-2 Bovine CAMLG protein Bovine
GM-Tg-equg-IP0245-Ab-1/ GM-Tg-equg-IP0245-Ab-2 Equine CAMLG protein Equine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No. GM-Tg-hg-IP0245-Ab-1/ GM-Tg-hg-IP0245-Ab-2; GM-Tg-rg-IP0245-Ab-1/ GM-Tg-rg-IP0245-Ab-2;
GM-Tg-mg-IP0245-Ab-1/ GM-Tg-mg-IP0245-Ab-2; GM-Tg-cynog-IP0245-Ab-1/ GM-Tg-cynog-IP0245-Ab-2;
GM-Tg-felg-IP0245-Ab-1/ GM-Tg-felg-IP0245-Ab-2; GM-Tg-cang-IP0245-Ab-1/ GM-Tg-cang-IP0245-Ab-2;
GM-Tg-bovg-IP0245-Ab-1/ GM-Tg-bovg-IP0245-Ab-2; GM-Tg-equg-IP0245-Ab-1/ GM-Tg-equg-IP0245-Ab-2
Products Name CAMLG protein
Species Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine
Target Name CAMLG
Protein Sub-location Introcelluar Protein
Isotypes Recombinant protein
Expression platform Mammalian cell
Bioactivity validation Affintiy&bioactivity validated by ELISA, cell culture validated.
Tag His
Products description Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine CAMLG protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic).
Purity Purity: ≥95% (SDS-PAGE)
Application In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference






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    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
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