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Target
sublocation: Introcelluar Protein.
This gene encodes a receptor that binds the Fc region of monomeric immunoglobulin G. The encoded protein transfers immunoglobulin G antibodies from mother to fetus across the placenta. This protein also binds immunoglobulin G to protect the antibody from degradation. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Apr 2009]
| Target ID |
GM-IP0110
|
| Target Name |
FcRn/FCGRT
|
Gene Group ldentifer (Target Gene ID in Homo
species)
|
2217
|
| Gene ID |
100147583 (Equus caballus), 101081512 (Felis catus), 114674122 (Macaca mulatta), 14132 (Mus musculus) 2217 (Homo sapiens), 29558 (Rattus norvegicus), 338062 (Bos taurus), 476414 (Canis lupus familiaris)
|
| Target Alternative Names |
FCGRT,FCRN,FcRn,FcgammaRn,Fcgrt,IgG Fc fragment receptor transporter alpha chain,IgG receptor FcRn large subunit p51,Neonatal Fc receptor,alpha-chain
|
| Uniprot Accession |
Q61559,P55899,P13599
|
| Protein Sub-location |
Introcelluar Protein
|
| Category |
Therapeutics Target, INN Index
|
| Gene Ensembl |
ENSECAG00000002855, ENSMMUG00000012273, ENSMUSG00000003420, ENSG00000104870, ENSBTAG00000013926, ENSCAFG00845023878
|
Pre-made viral vector of FcRn/FCGRT cDNA Clones/ORF Plasmid
FcRn/FCGRT siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo2217 | Pre-made Human FCGRT/FCRN/FcgammaRn siRNA oligo Duplex | 2217 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo29558 | Pre-made Rat Fcgrt/FcRn siRNA oligo Duplex | 29558 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo14132 | Pre-made Mouse Fcgrt/FcRn siRNA oligo Duplex | 14132 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo114674122 | Pre-made Cynomolgus/Rhesus macaque FCGRT siRNA oligo Duplex | 114674122 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101081512 | Pre-made Cat/Feline FCGRT/FcRn siRNA oligo Duplex | 101081512 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo476414 | Pre-made Dog/Canine FCGRT siRNA oligo Duplex | 476414 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo338062 | Pre-made Bovines/Cattle FCGRT siRNA oligo Duplex | 338062 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100147583 | Pre-made Equine/Horse FCGRT siRNA oligo Duplex | 100147583 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
FcRn/FCGRT antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-IP0110-Ab | Human | Anti-Human FcRn/FCGRT monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-rg-IP0110-Ab | Rat | Anti-Rat FcRn/FCGRT monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-mg-IP0110-Ab | Mouse | Anti-Mouse FcRn/FCGRT monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-cynog-IP0110-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque FcRn/FCGRT monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-felg-IP0110-Ab | Cat/Feline | Anti-Cat/Feline FcRn/FCGRT monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-cang-IP0110-Ab | Dog/Canine | Anti-Dog/Canine FcRn/FCGRT monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-bovg-IP0110-Ab | Bovines/Cattle | Anti-Bovines/Cattle FcRn/FCGRT monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-equg-IP0110-Ab | Equine/Horse | Anti-Equine/Horse FcRn/FCGRT monoclonal antibody | mab | Therapeutics Target antibody | Detail |
FcRn/FCGRT recombinant protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-IP0110-Ag | Human | Human FcRn/FCGRT recombinant protein | Mammalian cell | Detail |
| GM-Tg-rg-IP0110-Ag | Rat | Rat FcRn/FCGRT recombinant protein | Mammalian cell | Detail |
| GM-Tg-mg-IP0110-Ag | Mouse | Mouse FcRn/FCGRT recombinant protein | Mammalian cell | Detail |
| GM-Tg-cynog-IP0110-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque FcRn/FCGRT recombinant protein | Mammalian cell | Detail |
| GM-Tg-felg-IP0110-Ag | Cat/Feline | Cat/Feline FcRn/FCGRT recombinant protein | Mammalian cell | Detail |
| GM-Tg-cang-IP0110-Ag | Dog/Canine | Dog/Canine FcRn/FCGRT recombinant protein | Mammalian cell | Detail |
| GM-Tg-bovg-IP0110-Ag | Bovines/Cattle | Bovines/Cattle FcRn/FCGRT recombinant protein | Mammalian cell | Detail |
| GM-Tg-equg-IP0110-Ag | Equine/Horse | Equine/Horse FcRn/FCGRT recombinant protein | Mammalian cell | Detail |