Explore BCL2L2/BCL-W gene products and cross-species
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insights for Homo sapiens (human), Cynomolgus monkeys, rodents
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Target
sublocation: Introcelluar Protein.
This gene encodes a member of the BCL-2 protein family. The proteins of this family form hetero- or homodimers and act as anti- and pro-apoptotic regulators. Expression of this gene in cells has been shown to contribute to reduced cell apoptosis under cytotoxic conditions. Studies of the related gene in mice indicated a role in the survival of NGF- and BDNF-dependent neurons. Mutation and knockout studies of the mouse gene demonstrated an essential role in adult spermatogenesis. Alternative splicing results in multiple transcript variants. Read-through transcription also exists between this gene and the neighboring downstream PABPN1 (poly(A) binding protein, nuclear 1) gene. [provided by RefSeq, Dec 2010]
| Target ID |
GM-IP0051
|
| Target Name |
BCL2L2/BCL-W
|
Gene Group ldentifer
（Target Gene ID in Homo
species)
|
599
|
| Gene ID |
100055644 (Equus caballus), 12050 (Mus musculus), 599 (Homo sapiens), 60434 (Rattus norvegicus)
767601 (Bos taurus)
|
| Target Alternative Names |
Apoptosis regulator Bcl-W,BCL-W,BCL-WEL,BCL-WS,BCL2-L-2,BCL2L2,BCLW,Bcl-2-like protein 2,Bcl-w,Bcl2-L-2,Bcl2l2,Bclw,Gtrgal2,Gtrosa41,PPP1R51,RELA,bclw,c98
|
| Uniprot Accession |
P70345,Q92843,Q1RMX3
|
| Protein Sub-location |
Introcelluar Protein
|
| Category |
Therapeutics Target
|
| Disease |
cancer, Breast Cancer
|
| Gene Ensembl |
ENSECAG00000011652, ENSMUSG00000089682, ENSG00000129473, ENSBTAG00000019692
|
Pre-made viral vector of BCL2L2/BCL-W cDNA Clones/ORF Plasmid
BCL2L2/BCL-W siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo599 | Pre-made Human BCL2L2/BCLW/BCL-W siRNA oligo Duplex | 599 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo60434 | Pre-made Rat Bcl2l2/Bclw/BCL-W siRNA oligo Duplex | 60434 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo12050 | Pre-made Mouse Bcl2l2/c98/bclw siRNA oligo Duplex | 12050 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo767601 | Pre-made Bovines/Cattle BCL2L2/RELA siRNA oligo Duplex | 767601 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100055644 | Pre-made Equine/Horse BCL2L2 siRNA oligo Duplex | 100055644 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
BCL2L2/BCL-W antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-IP0051-Ab | Human | Anti-Human BCL2L2/BCL-W monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-rg-IP0051-Ab | Rat | Anti-Rat BCL2L2/BCL-W monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-mg-IP0051-Ab | Mouse | Anti-Mouse BCL2L2/BCL-W monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-bovg-IP0051-Ab | Bovines/Cattle | Anti-Bovines/Cattle BCL2L2/BCL-W monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-equg-IP0051-Ab | Equine/Horse | Anti-Equine/Horse BCL2L2/BCL-W monoclonal antibody | mab | Therapeutics Target antibody | Detail |
BCL2L2/BCL-W recombinant protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-IP0051-Ag | Human | Human BCL2L2/BCL-W recombinant protein | Mammalian cell | Detail |
| GM-Tg-rg-IP0051-Ag | Rat | Rat BCL2L2/BCL-W recombinant protein | Mammalian cell | Detail |
| GM-Tg-mg-IP0051-Ag | Mouse | Mouse BCL2L2/BCL-W recombinant protein | Mammalian cell | Detail |
| GM-Tg-bovg-IP0051-Ag | Bovines/Cattle | Bovines/Cattle BCL2L2/BCL-W recombinant protein | Mammalian cell | Detail |
| GM-Tg-equg-IP0051-Ag | Equine/Horse | Equine/Horse BCL2L2/BCL-W recombinant protein | Mammalian cell | Detail |
