Explore PDE4B gene products and cross-species
research data at TarMart platform. Discover comprehensive
biological information, expression tools, and therapeutic
insights for Homo sapiens (human), Cynomolgus monkeys, rodents
(mouse/rat), canines, felines, bovines, and equines. Your
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Target
sublocation: Introcelluar Protein.
This gene is a member of the type IV, cyclic AMP (cAMP)-specific, cyclic nucleotide phosphodiesterase (PDE) family. The encoded protein regulates the cellular concentrations of cyclic nucleotides and thereby play a role in signal transduction. Altered activity of this protein has been associated with schizophrenia and bipolar affective disorder. Alternative splicing and the use of alternative promoters results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2014]
| Target ID |
GM-IP0041
|
| Target Name |
PDE4B
|
Gene Group ldentifer
（Target Gene ID in Homo
species)
|
5142
|
| Gene ID |
100053961 (Equus caballus), 101081316 (Felis catus), 18578 (Mus musculus), 24626 (Rattus norvegicus)
479540 (Canis lupus familiaris), 5142 (Homo sapiens), 699309 (Macaca mulatta)
|
| Target Alternative Names |
3',5'-cyclic-AMP phosphodiesterase 4B,DPDE4,Dpde4,PDE32,PDE4/IVb,PDE4B,PDEIVB,Pde4B1,Pde4B2,Pde4B3,Pde4B4,Pde4b,Pde4b5,Pde4b_v1,Pde4b_v2,Pde4b_v3,Pde4b_v4,cAMP-specific phosphodiesterase 4B,dunce
|
| Uniprot Accession |
P14646,Q07343
|
| Protein Sub-location |
Introcelluar Protein
|
| Category |
Therapeutics Target
|
| Disease from KEGG |
Metabolic pathways, cAMP signaling pathway, Parathyroid hormone synthesis, secretion and action, Morphine addiction
|
| Gene Ensembl |
ENSECAG00000011003, ENSMUSG00000028525, ENSCAFG00845028786, ENSG00000184588, ENSMMUG00000007490
|
Pre-made viral vector of PDE4B cDNA Clones/ORF Plasmid
PDE4B siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo5142 | Pre-made Human PDE4B/DPDE4/PDEIVB siRNA oligo Duplex | 5142 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo24626 | Pre-made Rat Pde4b/Pde4B1/Pde4B2 siRNA oligo Duplex | 24626 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo18578 | Pre-made Mouse Pde4b/Dpde4/dunce siRNA oligo Duplex | 18578 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo699309 | Pre-made Cynomolgus/Rhesus macaque PDE4B siRNA oligo Duplex | 699309 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101081316 | Pre-made Cat/Feline PDE4B siRNA oligo Duplex | 101081316 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo479540 | Pre-made Dog/Canine PDE4B siRNA oligo Duplex | 479540 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100053961 | Pre-made Equine/Horse PDE4B siRNA oligo Duplex | 100053961 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
PDE4B antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-IP0041-Ab | Human | Anti-Human PDE4B monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-rg-IP0041-Ab | Rat | Anti-Rat PDE4B monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-mg-IP0041-Ab | Mouse | Anti-Mouse PDE4B monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-cynog-IP0041-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque PDE4B monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-felg-IP0041-Ab | Cat/Feline | Anti-Cat/Feline PDE4B monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-cang-IP0041-Ab | Dog/Canine | Anti-Dog/Canine PDE4B monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-equg-IP0041-Ab | Equine/Horse | Anti-Equine/Horse PDE4B monoclonal antibody | mab | Therapeutics Target antibody | Detail |
PDE4B recombinant protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-IP0041-Ag | Human | Human PDE4B recombinant protein | Mammalian cell | Detail |
| GM-Tg-rg-IP0041-Ag | Rat | Rat PDE4B recombinant protein | Mammalian cell | Detail |
| GM-Tg-mg-IP0041-Ag | Mouse | Mouse PDE4B recombinant protein | Mammalian cell | Detail |
| GM-Tg-cynog-IP0041-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque PDE4B recombinant protein | Mammalian cell | Detail |
| GM-Tg-felg-IP0041-Ag | Cat/Feline | Cat/Feline PDE4B recombinant protein | Mammalian cell | Detail |
| GM-Tg-cang-IP0041-Ag | Dog/Canine | Dog/Canine PDE4B recombinant protein | Mammalian cell | Detail |
| GM-Tg-equg-IP0041-Ag | Equine/Horse | Equine/Horse PDE4B recombinant protein | Mammalian cell | Detail |
