Explore Tyrosinase/TYR gene products and cross-species
research data at TarMart platform. Discover comprehensive
biological information, expression tools, and therapeutic
insights for Homo sapiens (human), Cynomolgus monkeys, rodents
(mouse/rat), canines, felines, bovines, and equines. Your
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Target
sublocation: Introcelluar Protein.
The enzyme encoded by this gene catalyzes the first 2 steps, and at least 1 subsequent step, in the conversion of tyrosine to melanin. The enzyme has both tyrosine hydroxylase and dopa oxidase catalytic activities, and requires copper for function. Mutations in this gene result in oculocutaneous albinism, and nonpathologic polymorphisms result in skin pigmentation variation. The human genome contains a pseudogene similar to the 3' half of this gene. [provided by RefSeq, Oct 2008]
| Target ID |
GM-IP0016
|
| Target Name |
Tyrosinase/TYR
|
Gene Group ldentifer
（Target Gene ID in Homo
species)
|
7299
|
| Gene ID |
100060227 (Equus caballus), 22173 (Mus musculus), 280951 (Bos taurus), 308800 (Rattus norvegicus)
403405 (Canis lupus familiaris), 705792 (Macaca mulatta), 7299 (Homo sapiens), 751100 (Felis catus)
|
| Target Alternative Names |
ATN,CMM8,LB24-AB,Monophenol monooxygenase,OCA1,OCA1A,OCAIA,Oca1,SHEP3,SK29-AB,TYR,Tumor rejection antigen AB,Tyr,Tyrosinase,albino,c,skc35
|
| Uniprot Accession |
P11344,Q8MIU0,P54834,P14679,P55033
|
| Protein Sub-location |
Introcelluar Protein
|
| Category |
Therapeutics Target, Immuno-oncology Target
|
| Disease from KEGG |
Metabolic pathways, Melanogenesis
|
| Gene Ensembl |
ENSECAG00000016425, ENSMUSG00000004651, ENSBTAG00000011813, ENSCAFG00845025889, ENSMMUG00000011115, ENSG00000077498
|
| Target Classification |
Checkpoint-Immuno Oncology
|
Pre-made viral vector of Tyrosinase/TYR cDNA Clones/ORF Plasmid
Tyrosinase/TYR siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo7299 | Pre-made Human TYR/ATN/CMM8 siRNA oligo Duplex | 7299 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo308800 | Pre-made Rat Tyr siRNA oligo Duplex | 308800 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo22173 | Pre-made Mouse Tyr/c/Oca1 siRNA oligo Duplex | 22173 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo705792 | Pre-made Cynomolgus/Rhesus macaque TYR siRNA oligo Duplex | 705792 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo751100 | Pre-made Cat/Feline TYR siRNA oligo Duplex | 751100 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo403405 | Pre-made Dog/Canine TYR siRNA oligo Duplex | 403405 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo280951 | Pre-made Bovines/Cattle TYR siRNA oligo Duplex | 280951 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100060227 | Pre-made Equine/Horse TYR siRNA oligo Duplex | 100060227 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
Tyrosinase/TYR antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-IP0016-Ab | Human | Anti-Human Tyrosinase/TYR monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-rg-IP0016-Ab | Rat | Anti-Rat Tyrosinase/TYR monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-mg-IP0016-Ab | Mouse | Anti-Mouse Tyrosinase/TYR monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-cynog-IP0016-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque Tyrosinase/TYR monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-felg-IP0016-Ab | Cat/Feline | Anti-Cat/Feline Tyrosinase/TYR monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-cang-IP0016-Ab | Dog/Canine | Anti-Dog/Canine Tyrosinase/TYR monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-bovg-IP0016-Ab | Bovines/Cattle | Anti-Bovines/Cattle Tyrosinase/TYR monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-equg-IP0016-Ab | Equine/Horse | Anti-Equine/Horse Tyrosinase/TYR monoclonal antibody | mab | Therapeutics Target antibody | Detail |
Tyrosinase/TYR recombinant protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-IP0016-Ag | Human | Human Tyrosinase/TYR recombinant protein | Mammalian cell | Detail |
| GM-Tg-rg-IP0016-Ag | Rat | Rat Tyrosinase/TYR recombinant protein | Mammalian cell | Detail |
| GM-Tg-mg-IP0016-Ag | Mouse | Mouse Tyrosinase/TYR recombinant protein | Mammalian cell | Detail |
| GM-Tg-cynog-IP0016-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque Tyrosinase/TYR recombinant protein | Mammalian cell | Detail |
| GM-Tg-felg-IP0016-Ag | Cat/Feline | Cat/Feline Tyrosinase/TYR recombinant protein | Mammalian cell | Detail |
| GM-Tg-cang-IP0016-Ag | Dog/Canine | Dog/Canine Tyrosinase/TYR recombinant protein | Mammalian cell | Detail |
| GM-Tg-bovg-IP0016-Ag | Bovines/Cattle | Bovines/Cattle Tyrosinase/TYR recombinant protein | Mammalian cell | Detail |
| GM-Tg-equg-IP0016-Ag | Equine/Horse | Equine/Horse Tyrosinase/TYR recombinant protein | Mammalian cell | Detail |
