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Human TYR/OCA1A/OCAIA ORF/cDNA clone-Adenovirus particle (BC027179)
Cat. No.: vGMAP000437
Pre-made Human TYR/OCA1A/OCAIA Adenovirus for TYR overexpression in-vitro and in-vivo. The TYR adenoviral vector excels as a vehicle for transient gene transfection in both stable cell lines and primary cells, including DC cells, macrophages, cardiomyocytes, hepatocytes, and neurons. The purified TYR-encoding adenovirus also stands out as a quintessential tool for in vivo studies and vaccine research initiatives.
At GM Vector Core (GMVC), we provide bespoke adenovirus development and manufacture various grades of adenoviruses utilizing cutting-edge techniques. Dive deeper into our offerings.
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Tyrosinase/TYR/TYR/OCA1A products
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Product information
| Catalog No. | Product Name | Adenovirus Grade | Adenovirus quantity |
| vGMAP000437 | Human TYR Adenovirus particle | Research Grade-In vitro | 1E+10PFU (1E+10pfu/ml×1ml) |
| 5E+10PFU (1E+10pfu/ml×5ml) | |||
| 1E+11PFU (1E+10pfu/ml×10ml) | |||
| Research Grade-In vivo | 1E+11PFU (1E+11pfu/ml×1ml) | ||
| GMP-like Grade | inquiry | ||
| GMP Grade | inquiry |
Product Description
| Catalog ID | vGMAP000437 |
| Gene Name | TYR |
| Accession Number | BC027179 |
| Gene ID | 7299 |
| Species | Human |
| Product Type | Adenovirus particle (overexpression) |
| Insert Length | 1134 bp |
| Gene Alias | OCA1A,OCAIA |
| Fluorescent Reporter | GFP |
| Mammalian Cell Selection | Null |
| Fusion Tag | 3xflag (C-Terminal) |
| Promoter | EF1 |
| Resistance | Amplicin |
| ORF Nucleotide Sequence | ATGCTCCTGGCTGTTTTGTACTGCCTGCTGTGGAGTTTCCAGACCTCCGCTGGCCATTTCCCTAGAGCCTGTGTCTCCTCTAAGAACCTGATGGAGAAGGAATGCTGTCCACCGTGGAGCGGGGACAGGAGTCCCTGTGGCCAGCTTTCAGGCAGAGGTTCCTGTCAGAATATCCTTCTGTCCAATGCACCACTTGGGCCTCAATTTCCCTTCACAGGGGTGGATGACCGGGAGTCGTGGCCTTCCGTCTTTTATAATAGGACCTGCCAGTGCTCTGGCAACTTCATGGGATTCAACTGTGGAAACTGCAAGTTTGGCTTTTGGGGACCAAACTGCACAGAGAGACGACTCTTGGTGAGAAGAAACATCTTCGATTTGAGTGCCCCAGAGAAGGACAAATTTTTTGCCTACCTCACTTTAGCAAAGCATACCATCAGCTCAGACTATGTCATCCCCATAGGGACCTATGGCCAAATGAAAAATGGATCAACACCCATGTTTAACGACATCAATATTTATGACCTCTTTGTCTGGATGCATTATTATGTGTCAATGGATGCACTGCTTGGGGGATCTGAAATCTGGAGAGACATTGATTTTGCCCATGAAGCACCAGCTTTTCTGCCTTGGCATAGACTCTTCTTGTTGCGGTGGGAACAAGAAATCCAGAAGCTGACAGGAGATGAAAACTTCACTATTCCATATTGGGACTGGCGGGATGCAGAAAAGTGTGACATTTGCACAGATGAGTACATGGGAGGTCAGCACCCCACAAATCCTAACTTACTCAGCCCAGCATCATTCTTCTCCTCTTGGCAGATTGTCTGTAGCCGATTGGAGGAGTACAACAGCCATCAGTCTTTATGCAATGGAACGCCCGAGGGACCTTTACGGCGTAATCCTGGAAACCATGACAAATCCAGAACCCCAAGGCTCCCCTCTTCAGCTGATGTAGAATTTTGCCTGAGTTTGACCCAATATGAATCTGGTTCCATGGATAAAGCTGCCAATTTCAGCTTTAGAAATACACTGGAAGAGATGGGATTTCTCCATGTTGGCTGGGCTGGTCTCAAACTCCTGACCTCAAGAGATCCACCACCTTGGCCTCCCAAAATGCTGGGATTACAGGCTTGA |
| ORF Protein Sequence | MLLAVLYCLLWSFQTSAGHFPRACVSSKNLMEKECCPPWSGDRSPCGQLSGRGSCQNILLSNAPLGPQFPFTGVDDRESWPSVFYNRTCQCSGNFMGFNCGNCKFGFWGPNCTERRLLVRRNIFDLSAPEKDKFFAYLTLAKHTISSDYVIPIGTYGQMKNGSTPMFNDINIYDLFVWMHYYVSMDALLGGSEIWRDIDFAHEAPAFLPWHRLFLLRWEQEIQKLTGDENFTIPYWDWRDAEKCDICTDEYMGGQHPTNPNLLSPASFFSSWQIVCSRLEEYNSHQSLCNGTPEGPLRRNPGNHDKSRTPRLPSSADVEFCLSLTQYESGSMDKAANFSFRNTLEEMGFLHVGWAGLKLLTSRDPPPWPPKMLGLQA |
Reference
Data / case study
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Associated products
| Category | Cat No. | Products Name |
|---|---|---|
| Target Antibody | GM-Tg-g-IP0016-Ab | Anti-TYR monoclonal antibody |
| Target Antigen | GM-Tg-g-IP0016-Ag | TYR protein |
| ORF Viral Vector | pGMAP000129 | Human TYR Adenovirus plasmid |
| ORF Viral Vector | pGMAP000437 | Human TYR Adenovirus plasmid |
| ORF Viral Vector | vGMAP000129 | Human TYR Adenovirus particle |
| ORF Viral Vector | vGMAP000437 | Human TYR Adenovirus particle |
Target information
| Target ID | GM-IP0016 |
| Target Name | Tyrosinase/TYR |
|
Gene Group Identifier （Target Gene ID in Homo species) |
7299 |
| Gene ID |
100060227 (Equus caballus), 22173 (Mus musculus), 280951 (Bos taurus), 308800 (Rattus norvegicus) 403405 (Canis lupus familiaris), 705792 (Macaca mulatta), 7299 (Homo sapiens), 751100 (Felis catus) |
| Gene Symbols & Synonyms | TYR,Tyr,c,Oca1,skc35,albino,ATN,CMM8,OCA1,OCA1A,OCAIA,SHEP3 |
| Target Alternative Names | ATN,CMM8,LB24-AB,Monophenol monooxygenase,OCA1,OCA1A,OCAIA,Oca1,SHEP3,SK29-AB,TYR,Tumor rejection antigen AB,Tyr,Tyrosinase,albino,c,skc35 |
| Uniprot Accession |
P11344,P14679,P54834,P55033,Q8MIU0
Additional SwissProt Accessions: P11344,Q8MIU0,P54834,P14679,P55033 |
| Uniprot Entry Name | |
| Protein Sub-location | Introcelluar Protein |
| Category | Therapeutics Target, Immuno-oncology Target |
| Disease | |
| Disease from KEGG | Metabolic pathways, Melanogenesis |
| Gene Ensembl | ENSECAG00000016425, ENSMUSG00000004651, ENSBTAG00000011813, ENSCAFG00845025889, ENSMMUG00000011115, ENSG00000077498 |
| Target Classification | Checkpoint-Immuno Oncology |
About GMVC
GMVC (GM Vector Core) is GeneMedi’s unique platform for QbD Viral vectors Processes development and manufacturing. In GMVC, our core expertise lies in the tailored production of viral vectors, including adeno-associated virus (AAV), lentivirus, and adenovirus. Our state-of-the-art facilities are equipped for scalable manufacturing, ensuring high-quality viral vector production to meet both research and therapeutic needs. Our expert team specializes in process development, leveraging innovative technology and extensive industry knowledge to provide clients with tailored solutions that exceed expectations. GMVC will be the ideal partner for scientists and healthcare professionals seeking reliable and efficient viral vector production services.