Explore CD63/LAMP gene products and cross-species
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biological information, expression tools, and therapeutic
insights for Homo sapiens (human), Cynomolgus monkeys, rodents
(mouse/rat), canines, felines, bovines, and equines. Your
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Target
sublocation: Transmembrane Protein.
The protein encoded by this gene is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. The encoded protein is a cell surface glycoprotein that is known to complex with integrins. It may function as a blood platelet activation marker. Deficiency of this protein is associated with Hermansky-Pudlak syndrome. Also this gene has been associated with tumor progression. Alternative splicing results in multiple transcript variants encoding different protein isoforms. [provided by RefSeq, Apr 2012]
| Target ID |
GM-IO085
|
| Target Name |
CD63/LAMP
|
Gene Group ldentifer (Target Gene ID in Homo
species)
|
967
|
| Gene ID |
100051450 (Equus caballus), 12512 (Mus musculus), 29186 (Rattus norvegicus), 404156 (Bos taurus) 474391 (Canis lupus familiaris), 493846 (Felis catus), 709828 (Macaca mulatta), 967 (Homo sapiens)
|
| Target Alternative Names |
AD1,CD63,CD63 antigen,Cd63,Granulophysin,HOP-26,LAMP,Lysosomal-associated membrane protein 3 (LAMP-3),Lysosome integral membrane protein 1 (Limp1),ME491,MLA1,Melanoma-associated antigen ME491,OMA81H,Ocular melanoma-associated antigen,Pltgp40,TSPAN30,Tetraspanin-30 (Tspan-30),Tspan30
|
| Uniprot Accession |
P41731,P28648,Q9XSK2,Q76B49,P08962
|
| Protein Sub-location |
Transmembrane Protein
|
| Category |
Therapeutics Target, Immuno-oncology Target
|
| Disease |
cancer
|
| Disease from KEGG |
Lysosome, Proteoglycans in cancer
|
| Gene Ensembl |
ENSECAG00000046524, ENSMUSG00000025351, ENSBTAG00000011931, ENSCAFG00845005463, ENSMMUG00000013232, ENSG00000135404
|
| Target Classification |
Checkpoint-Immuno Oncology, Tumor-associated antigen (TAA)
|
Pre-made viral vector of CD63/LAMP cDNA Clones/ORF Plasmid
CD63/LAMP siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo967 | Pre-made Human CD63/AD1/MLA1 siRNA oligo Duplex | 967 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo29186 | Pre-made Rat Cd63 siRNA oligo Duplex | 29186 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo12512 | Pre-made Mouse Cd63/ME491/Tspan30 siRNA oligo Duplex | 12512 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo709828 | Pre-made Cynomolgus/Rhesus macaque CD63 siRNA oligo Duplex | 709828 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo493846 | Pre-made Cat/Feline CD63 siRNA oligo Duplex | 493846 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo474391 | Pre-made Dog/Canine CD63 siRNA oligo Duplex | 474391 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo404156 | Pre-made Bovines/Cattle CD63 siRNA oligo Duplex | 404156 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100051450 | Pre-made Equine/Horse CD63 siRNA oligo Duplex | 100051450 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
CD63/LAMP antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-IO085-Ab | Human | Anti-Human CD63/LAMP monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-rg-IO085-Ab | Rat | Anti-Rat CD63/LAMP monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-mg-IO085-Ab | Mouse | Anti-Mouse CD63/LAMP monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-cynog-IO085-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque CD63/LAMP monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-felg-IO085-Ab | Cat/Feline | Anti-Cat/Feline CD63/LAMP monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-cang-IO085-Ab | Dog/Canine | Anti-Dog/Canine CD63/LAMP monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-bovg-IO085-Ab | Bovines/Cattle | Anti-Bovines/Cattle CD63/LAMP monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-equg-IO085-Ab | Equine/Horse | Anti-Equine/Horse CD63/LAMP monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
CD63/LAMP VLP (virus-like particle)/protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-IO085-Ag | Human | Human CD63/LAMP VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-rg-IO085-Ag | Rat | Rat CD63/LAMP VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-mg-IO085-Ag | Mouse | Mouse CD63/LAMP VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cynog-IO085-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque CD63/LAMP VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-felg-IO085-Ag | Cat/Feline | Cat/Feline CD63/LAMP VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cang-IO085-Ag | Dog/Canine | Dog/Canine CD63/LAMP VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-bovg-IO085-Ag | Bovines/Cattle | Bovines/Cattle CD63/LAMP VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-equg-IO085-Ag | Equine/Horse | Equine/Horse CD63/LAMP VLP (virus-like particle) | HEK293 | Products Developing |