HSPA1A: Target/Biomarker Introduction, products summarized (antibody/ADC/bispecific/antigen/ORF vector/VLP) and disease/indication/condition/MOA for drug discovery and IVD
It's the GeneMedi's summary page for Target/Biomarker Introduction of HSPA1A. The page also collects GeneMedi's different modalities and formats products for HSPA1A in therapeutics/drug discovery and IVD diagnostics, which is including antibody, ADC, bispecific, antigen, ORF vector, VLP, etc. With GeneMedi's target-insight database-GM ITD database, the HSPA1A target is also connected to human indications/diseases/conditions/MOA.
Target sublocation: Introcelluar Protein.
This intronless gene encodes a 70kDa heat shock protein which is a member of the heat shock protein 70 family. In conjuction with other heat shock proteins, this protein stabilizes existing proteins against aggregation and mediates the folding of newly translated proteins in the cytosol and in organelles. It is also involved in the ubiquitin-proteasome pathway through interaction with the AU-rich element RNA-binding protein 1. The gene is located in the major histocompatibility complex class III region, in a cluster with two closely related genes which encode similar proteins. [provided by RefSeq, Jul 2008]
| Target ID | GM-TA038 |
| Target Name | HSPA1A |
| Gene ID | 3303,193740,720054,282254 |
| Gene Symbol and Synonyms | HEL-S-103,hsp68,HSP70,HSP70-1,HSP70-1A,HSP70-2,Hsp70-3,HSP70.1,HSP70.2,Hsp70.3,hsp70A1,HSP70I,HSP72,HSPA1,HSPA1A,HSPA1B,HSPA2 |
| Uniprot Accession | P0DMV8,Q27965 |
| Uniprot Entry Name | HS71A_HUMAN,HS71B_BOVIN |
| Protein Sub-location | Introcelluar Protein |
| Category | Therapeutics Target |
| Disease | Malignant neoplasm of bladder |
| Gene Ensembl | ENSG00000204389 |
| Target Classification | N/A |
Pre-made anti-HSPA1A inhibitory monoclonal antibody(mab, blocking antibody inhibitor)-benchmark antibody for drug discovery and mechanism of action (MOA) research
Pre-made anti-HSPA1A monoclonal antibody(mab) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic). The anti-HSPA1A mab is expressed and produced by mammalian cell line as a benchmark reference therapeutic antibody for biological drug discovery items including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
| Antibody Name | Species | Format | Classified by tag | Detail |
| Anti-HSPA1A monoclonal antibody | Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine | mab | Therapeutics Target antibody | Detail |
Recombinant multi-species HS71A/ HSPA1A/ HEL-S-103 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis
Genemedi produces Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine HSPA1A protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
| Products Name | Species | Expression Platform | Detail |
| HSPA1A protein | Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine | Mammalian cell | Detail |
Pre-made HSPA1A viral vector in GM Promise-ORFTM
| Cat No. | Products name | NM ID | Species | Type | Detail |
| vGMAP000139 | Human HSPA1A Adenovirus particle | BC009322 | Human | Adenovirus particle | Detail |
| pGMAP000139 | Human HSPA1A Adenovirus plasmid | BC009322 | Human | Adenovirus plasmid | Detail |
| pGMLPm004065 | mouse Hspa1a Lentivirus plasmid | NM_010479.2 | Mouse | Lentivirus plasmid | Detail |
| vGMLPm004065 | mouse Hspa1a Lentivirus particle | NM_010479.2 | Mouse | Lentivirus particle | Detail |
About Promise-ORFTM:
Discover the largest collection of ORF/cDNA expression clones from different species, including human, mouse, rat, and more with GeneMedi's Promise-ORFTM. Our collection of ORFs expression clones come in verified mammalian or viral vectors lentivirus, AAV, and adenovirus) and our Promise-ORFTM viral-ready expression vectors make it easy for you to improve viral vector packaging efficiency or directly transfect mammalian cells, resulting in stronger and easier expression detection. Click to search your GOI
If you want to obtain higher quantities of plasmids (mg), please visit GM TransExcellent Plasmid DNA Rapid Preparation Service.