HSPA9: Target/Biomarker Introduction, products summarized (antibody/ADC/bispecific/antigen/ORF vector/VLP) and disease/indication/condition/MOA for drug discovery and IVD
It's the GeneMedi's summary page for Target/Biomarker Introduction of HSPA9. The page also collects GeneMedi's different modalities and formats products for HSPA9 in therapeutics/drug discovery and IVD diagnostics, which is including antibody, ADC, bispecific, antigen, ORF vector, VLP, etc. With GeneMedi's target-insight database-GM ITD database, the HSPA9 target is also connected to human indications/diseases/conditions/MOA.
Target sublocation: Introcelluar Protein.
This gene encodes a member of the heat shock protein 70 gene family. The encoded protein is primarily localized to the mitochondria but is also found in the endoplasmic reticulum, plasma membrane and cytoplasmic vesicles. This protein is a heat-shock cognate protein. This protein plays a role in cell proliferation, stress response and maintenance of the mitochondria. A pseudogene of this gene is found on chromosome 2.[provided by RefSeq, May 2010]
| Target ID | GM-T99909 |
| Target Name | HSPA9 |
| Gene ID | 3313,15526,291671,714506,474697,101089072,517535,100034032 |
| Gene Symbol and Synonyms | 74kDa,CRP40,CSA,EVPLS,GRP-75,GRP75,HEL-S-124m,Hsc74,Hsp74,Hsp74a,HSPA9,Hspa9a,HSPA9B,Mortalin,MOT,Mot-2,MOT2,Mthsp70,MTHSP75,PBP74,SAAN,SIDBA4 |
| Uniprot Accession | P38646,P48721,P99502,Q3ZCH0 |
| Uniprot Entry Name | GRP75_HUMAN,GRP75_RAT,GRP75_CANLF,GRP75_BOVIN |
| Protein Sub-location | Introcelluar Protein |
| Category | Therapeutics Target |
| Disease | Lung Cancer |
| Gene Ensembl | ENSG00000113013 |
| Target Classification | N/A |
Pre-made anti-HSPA9 inhibitory monoclonal antibody(mab, blocking antibody inhibitor)-benchmark antibody for drug discovery and mechanism of action (MOA) research
Pre-made anti-HSPA9 monoclonal antibody(mab) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic). The anti-HSPA9 mab is expressed and produced by mammalian cell line as a benchmark reference therapeutic antibody for biological drug discovery items including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
| Antibody Name | Species | Format | Classified by tag | Detail |
| Anti-HSPA9 monoclonal antibody | Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine | mab | Therapeutics Target antibody | Detail |
Recombinant multi-species GRP75/ HSPA9/ CRP40 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis
Genemedi produces Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine HSPA9 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
| Products Name | Species | Expression Platform | Detail |
| HSPA9 protein | Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine | Mammalian cell | Detail |
Pre-made HSPA9 viral vector in GM Promise-ORFTM
| Cat No. | Products name | NM ID | Species | Type | Detail |
| vGMLP002990 | human HSPA9 Lentivirus particle | NM_004134 | Human | Lentivirus particle | Detail |
| pGMLP002990 | human HSPA9 Lentivirus plasmid | NM_004134 | Human | Lentivirus plasmid | Detail |
| pGMAAV000229 | house mouse Hspa9 AAV plasmid | NM_010481 | House Mouse | AAV plasmid | Detail |
| pGMLPm004101 | mouse Hspa9 Lentivirus plasmid | NM_010481 | Mouse | Lentivirus plasmid | Detail |
| vGMAAV000229 | house mouse Hspa9 AAV particle | NM_010481 | House Mouse | AAV particle | Detail |
| vGMLPm004101 | mouse Hspa9 Lentivirus particle | NM_010481 | Mouse | Lentivirus particle | Detail |
About Promise-ORFTM:
Discover the largest collection of ORF/cDNA expression clones from different species, including human, mouse, rat, and more with GeneMedi's Promise-ORFTM. Our collection of ORFs expression clones come in verified mammalian or viral vectors lentivirus, AAV, and adenovirus) and our Promise-ORFTM viral-ready expression vectors make it easy for you to improve viral vector packaging efficiency or directly transfect mammalian cells, resulting in stronger and easier expression detection. Click to search your GOI
If you want to obtain higher quantities of plasmids (mg), please visit GM TransExcellent Plasmid DNA Rapid Preparation Service.