VDAC1: Target/Biomarker Introduction, products summarized (antibody/ADC/bispecific/antigen/ORF vector/VLP) and disease/indication/condition/MOA for drug discovery and IVD
It's the GeneMedi's summary page for Target/Biomarker Introduction of VDAC1. The page also collects GeneMedi's different modalities and formats products for VDAC1 in therapeutics/drug discovery and IVD diagnostics, which is including antibody, ADC, bispecific, antigen, ORF vector, VLP, etc. With GeneMedi's target-insight database-GM ITD database, the VDAC1 target is also connected to human indications/diseases/conditions/MOA.
Target sublocation: Transmembrane Protein.
This gene encodes a voltage-dependent anion channel protein that is a major component of the outer mitochondrial membrane. The encoded protein facilitates the exchange of metabolites and ions across the outer mitochondrial membrane and may regulate mitochondrial functions. This protein also forms channels in the plasma membrane and may be involved in transmembrane electron transport. Alternate splicing results in multiple transcript variants. Multiple pseudogenes of this gene are found on chromosomes 1, 2 3, 6, 9, 12, X and Y.[provided by RefSeq, Sep 2010]
| Target ID | GM-T99397 |
| Target Name | VDAC1 |
| Gene ID | 7416,22333,83529,710045,474681,101098515,282119,100062974 |
| Gene Symbol and Synonyms | mVDAC1,mVDAC5,PORIN,VDAC-1,VDAC1,Vdac5 |
| Uniprot Accession | P21796,Q9Z2L0,P45879 |
| Uniprot Entry Name | VDAC1_HUMAN,VDAC1_RAT,VDAC1_BOVIN |
| Protein Sub-location | Transmembrane Protein |
| Category | Therapeutics Target |
| Disease | N/A |
| Gene Ensembl | ENSG00000213585 |
| Target Classification | N/A |
Pre-made anti-VDAC1 inhibitory monoclonal antibody(mab, blocking antibody inhibitor)-benchmark antibody for drug discovery and mechanism of action (MOA) research
Pre-made anti-VDAC1 benchmark inhibitory monoclonal antibody(mab, blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, FACS, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic). The anti-VDAC1 mab is expressed and produced by mammalian cell line as a benchmark reference therapeutic antibody for biological drug discovery items including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
| Antibody Name | Species | Format | Classified by tag | Detail |
| Anti-VDAC1 monoclonal antibody | Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
Multi-species VDAC1/ PORIN/ VDAC-1 VLP (virus-like particle) for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis
Genemedi produces Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine VDAC1 VLP (virus-like particle) for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
| Products Name | Species | Expression Platform | Detail |
| VDAC1 VLP (virus-like particle) | Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine | Mammalian cell | Products Developing |
Pre-made VDAC1 viral vector in GM Promise-ORFTM
| Cat No. | Products name | NM ID | Species | Type | Detail |
| pGMLP004105 | human VDAC1 Lentivirus plasmid | NM_003374.2 | Human | Lentivirus plasmid | Detail |
| vGMLPm004021 | mouse VDAC1 Lentivirus particle | NM_003374.2 | Mouse | Lentivirus particle | Detail |
| vGMAP000083 | Human VDAC1 Adenovirus particle | BC008482 | Human | Adenovirus particle | Detail |
| pGMLP002015 | human VDAC1 Lentivirus plasmid | NM_003374.2 | Human | Lentivirus plasmid | Detail |
| pGMLPm004021 | mouse VDAC1 Lentivirus plasmid | NM_003374.2 | Mouse | Lentivirus plasmid | Detail |
| vGMLP002015 | human VDAC1 Lentivirus particle | NM_003374.2 | Human | Lentivirus particle | Detail |
| pGMAP000083 | Human VDAC1 Adenovirus plasmid | BC008482 | Human | Adenovirus plasmid | Detail |
| vGMLP004105 | human VDAC1 Lentivirus particle | NM_003374.2 | Human | Lentivirus particle | Detail |
| pGMLPm000469 | mouse Vdac1 Lentivirus plasmid | NM_011694 | Mouse | Lentivirus plasmid | Detail |
| vGMLPm000469 | mouse Vdac1 Lentivirus particle | NM_011694 | Mouse | Lentivirus particle | Detail |
About Promise-ORFTM:
Discover the largest collection of ORF/cDNA expression clones from different species, including human, mouse, rat, and more with GeneMedi's Promise-ORFTM. Our collection of ORFs expression clones come in verified mammalian or viral vectors lentivirus, AAV, and adenovirus) and our Promise-ORFTM viral-ready expression vectors make it easy for you to improve viral vector packaging efficiency or directly transfect mammalian cells, resulting in stronger and easier expression detection. Click to search your GOI
If you want to obtain higher quantities of plasmids (mg), please visit GM TransExcellent Plasmid DNA Rapid Preparation Service.