VDAC1: Target/Biomarker Introduction, products summarized (antibody/ADC/bispecific/antigen/ORF vector/VLP) and disease/indication/condition/MOA for drug discovery and IVD

It's the GeneMedi's summary page for Target/Biomarker Introduction of VDAC1. The page also collects GeneMedi's different modalities and formats products for VDAC1 in therapeutics/drug discovery and IVD diagnostics, which is including antibody, ADC, bispecific, antigen, ORF vector, VLP, etc. With GeneMedi's target-insight database-GM ITD database, the VDAC1 target is also connected to human indications/diseases/conditions/MOA.

Target sublocation: Transmembrane Protein.

This gene encodes a voltage-dependent anion channel protein that is a major component of the outer mitochondrial membrane. The encoded protein facilitates the exchange of metabolites and ions across the outer mitochondrial membrane and may regulate mitochondrial functions. This protein also forms channels in the plasma membrane and may be involved in transmembrane electron transport. Alternate splicing results in multiple transcript variants. Multiple pseudogenes of this gene are found on chromosomes 1, 2 3, 6, 9, 12, X and Y.[provided by RefSeq, Sep 2010]

Target IDGM-T99397
Target NameVDAC1
Gene ID7416,22333,83529,710045,474681,101098515,282119,100062974
Gene Symbol and SynonymsmVDAC1,mVDAC5,PORIN,VDAC-1,VDAC1,Vdac5
Uniprot AccessionP21796,Q9Z2L0,P45879
Uniprot Entry NameVDAC1_HUMAN,VDAC1_RAT,VDAC1_BOVIN
Protein Sub-locationTransmembrane Protein
CategoryTherapeutics Target
DiseaseN/A
Gene EnsemblENSG00000213585
Target ClassificationN/A


Pre-made anti-VDAC1 inhibitory monoclonal antibody(mab, blocking antibody inhibitor)-benchmark antibody for drug discovery and mechanism of action (MOA) research

Pre-made anti-VDAC1 benchmark inhibitory monoclonal antibody(mab, blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, FACS, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic). The anti-VDAC1 mab is expressed and produced by mammalian cell line as a benchmark reference therapeutic antibody for biological drug discovery items including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.

Antibody NameSpeciesFormatClassified by tagDetail
Anti-VDAC1 monoclonal antibodyHuman, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, EquinemabFACS/Biofunctional Antibody, Therapeutics Target antibodyDetail



Multi-species VDAC1/ PORIN/ VDAC-1 VLP (virus-like particle) for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

Genemedi produces Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine VDAC1 VLP (virus-like particle) for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.

Products NameSpeciesExpression PlatformDetail
VDAC1 VLP (virus-like particle)Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, EquineMammalian cellProducts Developing



Pre-made VDAC1 viral vector in GM Promise-ORFTM

Cat No.Products nameNM IDSpeciesTypeDetail
pGMLP004105human VDAC1 Lentivirus plasmidNM_003374.2HumanLentivirus plasmidDetail
vGMLPm004021mouse VDAC1 Lentivirus particleNM_003374.2MouseLentivirus particleDetail
vGMAP000083Human VDAC1 Adenovirus particleBC008482HumanAdenovirus particleDetail
pGMLP002015human VDAC1 Lentivirus plasmidNM_003374.2HumanLentivirus plasmidDetail
pGMLPm004021mouse VDAC1 Lentivirus plasmidNM_003374.2MouseLentivirus plasmidDetail
vGMLP002015human VDAC1 Lentivirus particleNM_003374.2HumanLentivirus particleDetail
pGMAP000083Human VDAC1 Adenovirus plasmidBC008482HumanAdenovirus plasmidDetail
vGMLP004105human VDAC1 Lentivirus particleNM_003374.2HumanLentivirus particleDetail
pGMLPm000469mouse Vdac1 Lentivirus plasmidNM_011694MouseLentivirus plasmidDetail
vGMLPm000469mouse Vdac1 Lentivirus particleNM_011694MouseLentivirus particleDetail

About Promise-ORFTM:
Discover the largest collection of ORF/cDNA expression clones from different species, including human, mouse, rat, and more with GeneMedi's Promise-ORFTM. Our collection of ORFs expression clones come in verified mammalian or viral vectors lentivirus, AAV, and adenovirus) and our Promise-ORFTM viral-ready expression vectors make it easy for you to improve viral vector packaging efficiency or directly transfect mammalian cells, resulting in stronger and easier expression detection. Click to search your GOI

If you want to obtain higher quantities of plasmids (mg), please visit GM TransExcellent Plasmid DNA Rapid Preparation Service.