MGF/KITLG: Target/Biomarker Introduction, products summarized (antibody/ADC/bispecific/antigen/ORF vector/VLP) and disease/indication/condition/MOA for drug discovery and IVD

It's the GeneMedi's summary page for Target/Biomarker Introduction of MGF/KITLG. The page also collects GeneMedi's different modalities and formats products for MGF in therapeutics/drug discovery and IVD diagnostics, which is including antibody, ADC, bispecific, antigen, ORF vector, VLP, etc. With GeneMedi's target-insight database-GM ITD database, the MGF target is also connected to human indications/diseases/conditions/MOA.

Target sublocation: Transmembrane Protein.

This gene encodes the ligand of the tyrosine-kinase receptor encoded by the KIT locus. This ligand is a pleiotropic factor that acts in utero in germ cell and neural cell development, and hematopoiesis, all believed to reflect a role in cell migration. In adults, it functions pleiotropically, while mostly noted for its continued requirement in hematopoiesis. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]

Target IDGM-T90089
Target NameMGF
Gene ID4254,17311,60427,574254,403507,493937,281885,100034127
Gene Symbol and Synonyms710-712,blz,Clo,Con,contrasted,CSF,DCUA,DFNA69,FPH2,FPHH,Gb,Kitl,KITLG,KL-1,MGF,SCF,SF,SHEP7,Sl,SLF,WS2F
Uniprot AccessionP21583,P21581,Q06220,P79169,Q28132,Q95MD2
Uniprot Entry NameSCF_HUMAN,SCF_RAT,SCF_FELCA,SCF_CANLF,SCF_BOVIN,SCF_HORSE
Protein Sub-locationTransmembrane Protein
CategoryTherapeutics Target
Diseasegastrointestinal stromal
Gene EnsemblENSG00000049130
Target ClassificationN/A


Pre-made anti-MGF inhibitory monoclonal antibody(mab, blocking antibody inhibitor)-benchmark antibody for drug discovery and mechanism of action (MOA) research

Pre-made anti-MGF benchmark inhibitory monoclonal antibody(mab, blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, FACS, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic). The anti-MGF mab is expressed and produced by mammalian cell line as a benchmark reference therapeutic antibody for biological drug discovery items including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.

Antibody NameSpeciesFormatClassified by tagDetail
Anti-MGF/KITLG monoclonal antibodyHuman, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, EquinemabFACS/Biofunctional Antibody, Therapeutics Target antibodyDetail



Multi-species SCF/ MGF/ KITLG VLP (virus-like particle) for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

Genemedi produces Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine MGF/KITLG VLP (virus-like particle) for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.

Products NameSpeciesExpression PlatformDetail
MGF/KITLG VLP (virus-like particle)Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, EquineMammalian cellProducts Developing



Pre-made KITLG viral vector in GM Promise-ORFTM

Cat No.Products nameNM IDSpeciesTypeDetail
vGMLP000478human KITLG Lentivirus particleNM_000899HumanLentivirus particleDetail
pGMLP000478human KITLG Lentivirus plasmidNM_000899HumanLentivirus plasmidDetail
pGMAP000370Human KITLG Adenovirus plasmidBC069783HumanAdenovirus plasmidDetail
vGMAP000370Human KITLG Adenovirus particleBC069783HumanAdenovirus particleDetail
pGMLPm001017mouse Kitl Lentivirus plasmidNM_001347156.1MouseLentivirus plasmidDetail
pGMLPm001018mouse Kitl Lentivirus plasmidNM_013598MouseLentivirus plasmidDetail
vGMLPm001017mouse Kitl Lentivirus particleNM_001347156.1MouseLentivirus particleDetail
vGMLPm001018mouse Kitl Lentivirus particleNM_013598MouseLentivirus particleDetail

About Promise-ORFTM:
Discover the largest collection of ORF/cDNA expression clones from different species, including human, mouse, rat, and more with GeneMedi's Promise-ORFTM. Our collection of ORFs expression clones come in verified mammalian or viral vectors lentivirus, AAV, and adenovirus) and our Promise-ORFTM viral-ready expression vectors make it easy for you to improve viral vector packaging efficiency or directly transfect mammalian cells, resulting in stronger and easier expression detection. Click to search your GOI

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