TFAP2A: Target/Biomarker Introduction, products summarized (antibody/ADC/bispecific/antigen/ORF vector/VLP) and disease/indication/condition/MOA for drug discovery and IVD
It's the GeneMedi's summary page for Target/Biomarker Introduction of TFAP2A. The page also collects GeneMedi's different modalities and formats products for TFAP2A in therapeutics/drug discovery and IVD diagnostics, which is including antibody, ADC, bispecific, antigen, ORF vector, VLP, etc. With GeneMedi's target-insight database-GM ITD database, the TFAP2A target is also connected to human indications/diseases/conditions/MOA.
Target sublocation: Introcelluar Protein.
The protein encoded by this gene is a transcription factor that binds the consensus sequence 5'-GCCNNNGGC-3'. The encoded protein functions as either a homodimer or as a heterodimer with similar family members. This protein activates the transcription of some genes while inhibiting the transcription of others. Defects in this gene are a cause of branchiooculofacial syndrome (BOFS). Three transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Dec 2009]
| Target ID | GM-T71317 |
| Target Name | TFAP2A |
| Gene ID | 7020,21418,306862,700663,488213,101096393,505849,100063009 |
| Gene Symbol and Synonyms | AP-2,Ap-2 (a),AP-2alpha,Ap2,AP2alpha,AP2TF,BOFS,Tcfap2a,TFAP2,TFAP2A |
| Uniprot Accession | P05549,P58197,A1A4R9 |
| Uniprot Entry Name | AP2A_HUMAN,AP2A_RAT,AP2A_BOVIN |
| Protein Sub-location | Introcelluar Protein |
| Category | Therapeutics Target |
| Disease | N/A |
| Gene Ensembl | ENSG00000137203 |
| Target Classification | N/A |
Pre-made anti-TFAP2A inhibitory monoclonal antibody(mab, blocking antibody inhibitor)-benchmark antibody for drug discovery and mechanism of action (MOA) research
Pre-made anti-TFAP2A monoclonal antibody(mab) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic). The anti-TFAP2A mab is expressed and produced by mammalian cell line as a benchmark reference therapeutic antibody for biological drug discovery items including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
| Antibody Name | Species | Format | Classified by tag | Detail |
| Anti-TFAP2A monoclonal antibody | Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine | mab | Therapeutics Target antibody | Detail |
Recombinant multi-species AP2A/ TFAP2A/ AP-2 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis
Genemedi produces Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine TFAP2A protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
| Products Name | Species | Expression Platform | Detail |
| TFAP2A protein | Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine | Mammalian cell | Detail |
Pre-made TFAP2A viral vector in GM Promise-ORFTM
| Cat No. | Products name | NM ID | Species | Type | Detail |
| vGMAP000248 | Human TFAP2A Adenovirus particle | BC017754 | Human | Adenovirus particle | Detail |
| pGMAP000421 | Human TFAP2A Adenovirus plasmid | BC017754 | Human | Adenovirus plasmid | Detail |
| vGMAP000421 | Human TFAP2A Adenovirus particle | BC017754 | Human | Adenovirus particle | Detail |
| pGMAP000248 | Human TFAP2A Adenovirus plasmid | BC017754 | Human | Adenovirus plasmid | Detail |
| pGMLPm005294 | mouse Tfap2a Lentivirus plasmid | NM_001301674.1 | Mouse | Lentivirus plasmid | Detail |
| vGMLPm005294 | mouse Tfap2a Lentivirus particle | NM_001301674.1 | Mouse | Lentivirus particle | Detail |
About Promise-ORFTM:
Discover the largest collection of ORF/cDNA expression clones from different species, including human, mouse, rat, and more with GeneMedi's Promise-ORFTM. Our collection of ORFs expression clones come in verified mammalian or viral vectors lentivirus, AAV, and adenovirus) and our Promise-ORFTM viral-ready expression vectors make it easy for you to improve viral vector packaging efficiency or directly transfect mammalian cells, resulting in stronger and easier expression detection. Click to search your GOI
If you want to obtain higher quantities of plasmids (mg), please visit GM TransExcellent Plasmid DNA Rapid Preparation Service.