BTLA: Target/Biomarker Introduction, products summarized (antibody/ADC/bispecific/antigen/ORF vector/VLP) and disease/indication/condition/MOA for drug discovery and IVD
It's the GeneMedi's summary page for Target/Biomarker Introduction of BTLA. The page also collects GeneMedi's different modalities and formats products for BTLA in therapeutics/drug discovery and IVD diagnostics, which is including antibody, ADC, bispecific, antigen, ORF vector, VLP, etc. With GeneMedi's target-insight database-GM ITD database, the BTLA target is also connected to human indications/diseases/conditions/MOA.
Target sublocation: Transmembrane Protein.
This gene encodes a member of the immunoglobulin superfamily. The encoded protein contains a single immunoglobulin (Ig) domain and is a receptor that relays inhibitory signals to suppress the immune response. Alternative splicing results in multiple transcript variants. Polymorphisms in this gene have been associated with an increased risk of rheumatoid arthritis. [provided by RefSeq, Aug 2011]
Target ID | GM-T68001 |
Target Name | BTLA |
Gene ID | 151888,208154,407756,708202,487975,101088181,531767,100071491 |
Gene Symbol and Synonyms | A630002H24,BTLA,BTLA1,CD272 |
Uniprot Accession | Q7Z6A9,Q6PNM1 |
Uniprot Entry Name | BTLA_HUMAN,BTLA_RAT |
Protein Sub-location | Transmembrane Protein |
Category | Therapeutics Target, INN Index |
Disease | N/A |
Gene Ensembl | ENSG00000186265 |
Target Classification | N/A |
Pre-made BTLA-specific INN-index biosimilar (antibody&conjugates)
Anti-BTLA therapeutic INN-index antibodies and conjugates are biosimilars expressed by mammalian cell line as a benchmark reference therapeutic antibody for drug discovery, target MOA research, cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic).
Cat No. | Products Name (INN Index) | INN Name | Previous Name | Target | Format | Detail |
GMP-Bios-ab-258 | Pre-Made Icatolimab biosimilar, Whole mAb, Anti-BTLA Antibody: Anti-CD272 therapeutic antibody | Icatolimab | tifcemalimab | BTLA | Whole mAb | Detail |
Click to check more INN-indexed antibody & protein biosimilar
Pre-made anti-BTLA inhibitory monoclonal antibody(mab, blocking antibody inhibitor)-benchmark antibody for drug discovery and mechanism of action (MOA) research
Pre-made anti-BTLA benchmark inhibitory monoclonal antibody(mab, blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, FACS, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic). The anti-BTLA mab is expressed and produced by mammalian cell line as a benchmark reference therapeutic antibody for biological drug discovery items including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Antibody Name | Species | Format | Classified by tag | Detail |
Anti-BTLA monoclonal antibody | Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
Multi-species BTLA/ BTLA1/ CD272 VLP (virus-like particle) for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis
Genemedi produces Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine BTLA VLP (virus-like particle) for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
Products Name | Species | Expression Platform | Detail |
BTLA VLP (virus-like particle) | Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine | Mammalian cell | Products Developing |
Pre-made BTLA viral vector in GM Promise-ORFTM
Cat No. | Products name | NM ID | Species | Type | Detail |
pGMLP001882 | human BTLA Lentivirus plasmid | NM_181780.3 | Human | Lentivirus plasmid | Detail |
vGMLP001882 | human BTLA Lentivirus particle | NM_181780.3 | Human | Lentivirus particle | Detail |
pGMLPm001940 | mouse Btla Lentivirus plasmid | NM_001037719 | Mouse | Lentivirus plasmid | Detail |
vGMLPm001940 | mouse Btla Lentivirus particle | NM_001037719 | Mouse | Lentivirus particle | Detail |
About Promise-ORFTM:
Discover the largest collection of ORF/cDNA expression clones from different species, including human, mouse, rat, and more with GeneMedi's Promise-ORFTM. Our collection of ORFs expression clones come in verified mammalian or viral vectors lentivirus, AAV, and adenovirus) and our Promise-ORFTM viral-ready expression vectors make it easy for you to improve viral vector packaging efficiency or directly transfect mammalian cells, resulting in stronger and easier expression detection. Click to search your GOI
If you want to obtain higher quantities of plasmids (mg), please visit GM TransExcellent Plasmid DNA Rapid Preparation Service.