RHOB: Target/Biomarker Introduction, products summarized (antibody/ADC/bispecific/antigen/ORF vector/VLP) and disease/indication/condition/MOA for drug discovery and IVD
It's the GeneMedi's summary page for Target/Biomarker Introduction of RHOB. The page also collects GeneMedi's different modalities and formats products for RHOB in therapeutics/drug discovery and IVD diagnostics, which is including antibody, ADC, bispecific, antigen, ORF vector, VLP, etc. With GeneMedi's target-insight database-GM ITD database, the RHOB target is also connected to human indications/diseases/conditions/MOA.
Target sublocation: Introcelluar Protein.
Predicted to enable GTP binding activity; GTPase activity; and protein kinase binding activity. Involved in several processes, including cellular response to hydrogen peroxide; cellular response to ionizing radiation; and regulation of cell migration. Located in cleavage furrow and endosome membrane. Biomarker of breast cancer. [provided by Alliance of Genome Resources, Apr 2022]
| Target ID | GM-T58361 |
| Target Name | RHOB |
| Gene ID | 388,11852,64373,702141,403670,101099371,515118,100056328 |
| Gene Symbol and Synonyms | ARH6,ARHB,MST081,MSTP081,RHO,RHOB,RHOH6 |
| Uniprot Accession | P62745,P62747,Q3ZBW5 |
| Uniprot Entry Name | RHOB_HUMAN,RHOB_RAT,RHOB_BOVIN |
| Protein Sub-location | Introcelluar Protein |
| Category | Therapeutics Target |
| Disease | Cancer |
| Gene Ensembl | ENSG00000143878 |
| Target Classification | Tumor-associated antigen (TAA) |
Pre-made anti-RHOB inhibitory monoclonal antibody(mab, blocking antibody inhibitor)-benchmark antibody for drug discovery and mechanism of action (MOA) research
Pre-made anti-RHOB monoclonal antibody(mab) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic). The anti-RHOB mab is expressed and produced by mammalian cell line as a benchmark reference therapeutic antibody for biological drug discovery items including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
| Antibody Name | Species | Format | Classified by tag | Detail |
| Anti-RHOB monoclonal antibody | Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine | mab | Therapeutics Target antibody | Detail |
Recombinant multi-species RHOB/ ARH6/ ARHB protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis
Genemedi produces Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine RHOB protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
| Products Name | Species | Expression Platform | Detail |
| RHOB protein | Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine | Mammalian cell | Detail |
Pre-made RHOB viral vector in GM Promise-ORFTM
| Cat No. | Products name | NM ID | Species | Type | Detail |
| vGMLP001841 | human RHOB Lentivirus particle | NM_004040 | Human | Lentivirus particle | Detail |
| pGMLP001028 | human RHOB Lentivirus plasmid | NM_004040 | Human | Lentivirus plasmid | Detail |
| pGMLP001841 | human RHOB Lentivirus plasmid | NM_004040 | Human | Lentivirus plasmid | Detail |
| vGMLP001028 | human RHOB Lentivirus particle | NM_004040 | Human | Lentivirus particle | Detail |
| pGMLPm001205 | mouse Rhob Lentivirus plasmid | NM_007483 | Mouse | Lentivirus plasmid | Detail |
| vGMLPm001205 | mouse Rhob Lentivirus particle | NM_007483 | Mouse | Lentivirus particle | Detail |
About Promise-ORFTM:
Discover the largest collection of ORF/cDNA expression clones from different species, including human, mouse, rat, and more with GeneMedi's Promise-ORFTM. Our collection of ORFs expression clones come in verified mammalian or viral vectors lentivirus, AAV, and adenovirus) and our Promise-ORFTM viral-ready expression vectors make it easy for you to improve viral vector packaging efficiency or directly transfect mammalian cells, resulting in stronger and easier expression detection. Click to search your GOI
If you want to obtain higher quantities of plasmids (mg), please visit GM TransExcellent Plasmid DNA Rapid Preparation Service.