UCHL1: Target/Biomarker Introduction, products summarized (antibody/ADC/bispecific/antigen/ORF vector/VLP) and disease/indication/condition/MOA for drug discovery and IVD
It's the GeneMedi's summary page for Target/Biomarker Introduction of UCHL1. The page also collects GeneMedi's different modalities and formats products for UCHL1 in therapeutics/drug discovery and IVD diagnostics, which is including antibody, ADC, bispecific, antigen, ORF vector, VLP, etc. With GeneMedi's target-insight database-GM ITD database, the UCHL1 target is also connected to human indications/diseases/conditions/MOA.
Target sublocation: Introcelluar Protein.
The protein encoded by this gene belongs to the peptidase C12 family. This enzyme is a thiol protease that hydrolyzes a peptide bond at the C-terminal glycine of ubiquitin. This gene is specifically expressed in the neurons and in cells of the diffuse neuroendocrine system. Mutations in this gene may be associated with Parkinson disease.[provided by RefSeq, Sep 2009]
| Target ID | GM-T56051 |
| Target Name | UCHL1 |
| Gene ID | 7345,22223,29545,701579,479098,101093604,514394,100033838 |
| Gene Symbol and Synonyms | gad,HEL-117,HEL-S-53,NDGOA,PARK5,PGP 9.5,PGP9.5,PGP95,SPG79,SPG79A,Uch-L1,UCHL-1,UCHL1 |
| Uniprot Accession | P09936,Q00981,P23356,Q9GM50 |
| Uniprot Entry Name | UCHL1_HUMAN,UCHL1_RAT,UCHL1_BOVIN,UCHL1_HORSE |
| Protein Sub-location | Introcelluar Protein |
| Category | Therapeutics Target |
| Disease | Lung Cancer |
| Gene Ensembl | ENSG00000154277 |
| Target Classification | N/A |
Pre-made anti-UCHL1 inhibitory monoclonal antibody(mab, blocking antibody inhibitor)-benchmark antibody for drug discovery and mechanism of action (MOA) research
Pre-made anti-UCHL1 monoclonal antibody(mab) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic). The anti-UCHL1 mab is expressed and produced by mammalian cell line as a benchmark reference therapeutic antibody for biological drug discovery items including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
| Antibody Name | Species | Format | Classified by tag | Detail |
| Anti-UCHL1 monoclonal antibody | Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine | mab | Therapeutics Target antibody | Detail |
Recombinant multi-species UCHL1/ HEL-117/ HEL-S-53 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis
Genemedi produces Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine UCHL1 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
| Products Name | Species | Expression Platform | Detail |
| UCHL1 protein | Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine | Mammalian cell | Detail |
Pre-made UCHL1 viral vector in GM Promise-ORFTM
| Cat No. | Products name | NM ID | Species | Type | Detail |
| vGMLP002703 | human UCHL1 Lentivirus particle | NM_004181 | Human | Lentivirus particle | Detail |
| pGMLP002703 | human UCHL1 Lentivirus plasmid | NM_004181 | Human | Lentivirus plasmid | Detail |
| pGMLV000740 | Norway rat Uchl1 Lentivirus plasmid | NM_017237.3 | Norway Rat | Lentivirus plasmid | Detail |
| pGMLPm001159 | mouse Uchl1 Lentivirus plasmid | NM_011670.2 | Mouse | Lentivirus plasmid | Detail |
| vGMLV000740 | Norway rat Uchl1 Lentivirus particle | NM_017237.3 | Norway Rat | Lentivirus particle | Detail |
| vGMLPm001159 | mouse Uchl1 Lentivirus particle | NM_011670.2 | Mouse | Lentivirus particle | Detail |
About Promise-ORFTM:
Discover the largest collection of ORF/cDNA expression clones from different species, including human, mouse, rat, and more with GeneMedi's Promise-ORFTM. Our collection of ORFs expression clones come in verified mammalian or viral vectors lentivirus, AAV, and adenovirus) and our Promise-ORFTM viral-ready expression vectors make it easy for you to improve viral vector packaging efficiency or directly transfect mammalian cells, resulting in stronger and easier expression detection. Click to search your GOI
If you want to obtain higher quantities of plasmids (mg), please visit GM TransExcellent Plasmid DNA Rapid Preparation Service.