KRT19: Target/Biomarker Introduction, products summarized (antibody/ADC/bispecific/antigen/ORF vector/VLP) and disease/indication/condition/MOA for drug discovery and IVD
It's the GeneMedi's summary page for Target/Biomarker Introduction of KRT19. The page also collects GeneMedi's different modalities and formats products for KRT19 in therapeutics/drug discovery and IVD diagnostics, which is including antibody, ADC, bispecific, antigen, ORF vector, VLP, etc. With GeneMedi's target-insight database-GM ITD database, the KRT19 target is also connected to human indications/diseases/conditions/MOA.
Target sublocation: Introcelluar Protein.
The protein encoded by this gene is a member of the keratin family. The keratins are intermediate filament proteins responsible for the structural integrity of epithelial cells and are subdivided into cytokeratins and hair keratins. The type I cytokeratins consist of acidic proteins which are arranged in pairs of heterotypic keratin chains. Unlike its related family members, this smallest known acidic cytokeratin is not paired with a basic cytokeratin in epithelial cells. It is specifically expressed in the periderm, the transiently superficial layer that envelopes the developing epidermis. The type I cytokeratins are clustered in a region of chromosome 17q12-q21. [provided by RefSeq, Jul 2008]
| Target ID | GM-T54461 |
| Target Name | KRT19 |
| Gene ID | 3880,16669,360626,101090662,100147127 |
| Gene Symbol and Synonyms | CK-19,CK19,EndoC,K19,K1CS,Ka19,Krt-1.19,Krt1-19,KRT19 |
| Uniprot Accession | P08727,Q63279 |
| Uniprot Entry Name | K1C19_HUMAN,K1C19_RAT |
| Protein Sub-location | Introcelluar Protein |
| Category | Therapeutics Target |
| Disease | Breast Cancer, Ovary Cancer, Endometriosis, Malignant neoplasm of bladder |
| Gene Ensembl | ENSG00000171345 |
| Target Classification | N/A |
Pre-made anti-KRT19 inhibitory monoclonal antibody(mab, blocking antibody inhibitor)-benchmark antibody for drug discovery and mechanism of action (MOA) research
Pre-made anti-KRT19 monoclonal antibody(mab) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic). The anti-KRT19 mab is expressed and produced by mammalian cell line as a benchmark reference therapeutic antibody for biological drug discovery items including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
| Antibody Name | Species | Format | Classified by tag | Detail |
| Anti-KRT19 monoclonal antibody | Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine | mab | Therapeutics Target antibody | Detail |
Recombinant multi-species K1C19/ KRT19/ CK19 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis
Genemedi produces Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine KRT19 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
| Products Name | Species | Expression Platform | Detail |
| KRT19 protein | Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine | Mammalian cell | Detail |
Pre-made KRT19 viral vector in GM Promise-ORFTM
| Cat No. | Products name | NM ID | Species | Type | Detail |
| pGMAP000435 | Human KRT19 Adenovirus plasmid | BC007628 | Human | Adenovirus plasmid | Detail |
| vGMAP000089 | Human KRT19 Adenovirus particle | BC007628 | Human | Adenovirus particle | Detail |
| vGMAP000435 | Human KRT19 Adenovirus particle | BC007628 | Human | Adenovirus particle | Detail |
| pGMLP003887 | human KRT19 Lentivirus plasmid | BC007628 | Human | Lentivirus plasmid | Detail |
| pGMAP000089 | Human KRT19 Adenovirus plasmid | BC007628 | Human | Adenovirus plasmid | Detail |
| vGMLP003887 | human KRT19 Lentivirus particle | BC007628 | Human | Lentivirus particle | Detail |
| pGMLPm002327 | mouse Krt19 Lentivirus plasmid | NM_008471 | Mouse | Lentivirus plasmid | Detail |
| vGMLPm002327 | mouse Krt19 Lentivirus particle | NM_008471 | Mouse | Lentivirus particle | Detail |
About Promise-ORFTM:
Discover the largest collection of ORF/cDNA expression clones from different species, including human, mouse, rat, and more with GeneMedi's Promise-ORFTM. Our collection of ORFs expression clones come in verified mammalian or viral vectors lentivirus, AAV, and adenovirus) and our Promise-ORFTM viral-ready expression vectors make it easy for you to improve viral vector packaging efficiency or directly transfect mammalian cells, resulting in stronger and easier expression detection. Click to search your GOI
If you want to obtain higher quantities of plasmids (mg), please visit GM TransExcellent Plasmid DNA Rapid Preparation Service.