STK4: Target/Biomarker Introduction, products summarized (antibody/ADC/bispecific/antigen/ORF vector/VLP) and disease/indication/condition/MOA for drug discovery and IVD
It's the GeneMedi's summary page for Target/Biomarker Introduction of STK4. The page also collects GeneMedi's different modalities and formats products for STK4 in therapeutics/drug discovery and IVD diagnostics, which is including antibody, ADC, bispecific, antigen, ORF vector, VLP, etc. With GeneMedi's target-insight database-GM ITD database, the STK4 target is also connected to human indications/diseases/conditions/MOA.
Target sublocation: Introcelluar Protein.
The protein encoded by this gene is a cytoplasmic kinase that is structurally similar to the yeast Ste20p kinase, which acts upstream of the stress-induced mitogen-activated protein kinase cascade. The encoded protein can phosphorylate myelin basic protein and undergoes autophosphorylation. A caspase-cleaved fragment of the encoded protein has been shown to be capable of phosphorylating histone H2B. The particular phosphorylation catalyzed by this protein has been correlated with apoptosis, and it's possible that this protein induces the chromatin condensation observed in this process. [provided by RefSeq, Jul 2008]
Target ID | GM-T47164 |
Target Name | STK4 |
Gene ID | 6789,58231,311622,717730,477240,101091185,514886,100070861 |
Gene Symbol and Synonyms | Kas-2,KRS2,MST1,STK4,YSK3 |
Uniprot Accession | Q13043,A4K2T0,Q5E9L6 |
Uniprot Entry Name | STK4_HUMAN,STK4_MACMU,STK4_BOVIN |
Protein Sub-location | Introcelluar Protein |
Category | Therapeutics Target |
Disease | N/A |
Gene Ensembl | ENSG00000101109 |
Target Classification | Kinase |
Pre-made anti-STK4 inhibitory monoclonal antibody(mab, blocking antibody inhibitor)-benchmark antibody for drug discovery and mechanism of action (MOA) research
Pre-made anti-STK4 monoclonal antibody(mab) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic). The anti-STK4 mab is expressed and produced by mammalian cell line as a benchmark reference therapeutic antibody for biological drug discovery items including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Antibody Name | Species | Format | Classified by tag | Detail |
Anti-STK4 monoclonal antibody | Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine | mab | Therapeutics Target antibody | Detail |
Recombinant multi-species STK4/ KRS2/ MST1 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis
Genemedi produces Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine STK4 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
Products Name | Species | Expression Platform | Detail |
STK4 protein | Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine | Mammalian cell | Detail |
Pre-made STK4 viral vector in GM Promise-ORFTM
Cat No. | Products name | NM ID | Species | Type | Detail |
vGMLP001370 | human STK4 Lentivirus particle | NM_006282 | Human | Lentivirus particle | Detail |
pGMLP001357 | human STK4 Lentivirus plasmid | NM_006282 | Human | Lentivirus plasmid | Detail |
vGMLP001357 | human STK4 Lentivirus particle | NM_006282 | Human | Lentivirus particle | Detail |
pGMLP001370 | human STK4 Lentivirus plasmid | NM_006282 | Human | Lentivirus plasmid | Detail |
pGMAD000306 | mouse Stk4 Adenovirus plasmid | NM_021420.3 | Mouse | Adenovirus plasmid | Detail |
pGMAAV000257 | house mouse Stk4 AAV plasmid | NM_021420.4 | House Mouse | AAV plasmid | Detail |
vGMAD000306 | mouse Stk4 Adenovirus particle | NM_021420.3 | Mouse | Adenovirus particle | Detail |
vGMAAV000257 | house mouse Stk4 AAV particle | NM_021420.4 | House Mouse | AAV particle | Detail |
About Promise-ORFTM:
Discover the largest collection of ORF/cDNA expression clones from different species, including human, mouse, rat, and more with GeneMedi's Promise-ORFTM. Our collection of ORFs expression clones come in verified mammalian or viral vectors lentivirus, AAV, and adenovirus) and our Promise-ORFTM viral-ready expression vectors make it easy for you to improve viral vector packaging efficiency or directly transfect mammalian cells, resulting in stronger and easier expression detection. Click to search your GOI
If you want to obtain higher quantities of plasmids (mg), please visit GM TransExcellent Plasmid DNA Rapid Preparation Service.