ABAD/HSD17B10: Target/Biomarker Introduction, products summarized (antibody/ADC/bispecific/antigen/ORF vector/VLP) and disease/indication/condition/MOA for drug discovery and IVD
It's the GeneMedi's summary page for Target/Biomarker Introduction of ABAD/HSD17B10. The page also collects GeneMedi's different modalities and formats products for ABAD in therapeutics/drug discovery and IVD diagnostics, which is including antibody, ADC, bispecific, antigen, ORF vector, VLP, etc. With GeneMedi's target-insight database-GM ITD database, the ABAD target is also connected to human indications/diseases/conditions/MOA.
Target sublocation: Introcelluar Protein.
This gene encodes 3-hydroxyacyl-CoA dehydrogenase type II, a member of the short-chain dehydrogenase/reductase superfamily. The gene product is a mitochondrial protein that catalyzes the oxidation of a wide variety of fatty acids and steroids, and is a subunit of mitochondrial ribonuclease P, which is involved in tRNA maturation. The protein has been implicated in the development of Alzheimer disease, and mutations in the gene are the cause of 17beta-hydroxysteroid dehydrogenase type 10 (HSD10) deficiency. Several alternatively spliced transcript variants have been identified, but the full-length nature of only two transcript variants has been determined. [provided by RefSeq, Aug 2014]
| Target ID | GM-T26923 |
| Target Name | ABAD |
| Gene ID | 3028,15108,63864,700018,480930,101090672,281809,100060335 |
| Gene Symbol and Synonyms | 17b-HSD10,17bHSD10,ABAD,Ads9,CAMR,DUPXp11.22,ERAB,HADH2,HCD2,HSD10,HSD10MD,HSD17B10,MHBD,MRPP2,MRX17,MRX31,MRXS10,SCHAD,SDR5C1 |
| Uniprot Accession | Q99714,O70351,O02691 |
| Uniprot Entry Name | HCD2_HUMAN,HCD2_RAT,HCD2_BOVIN |
| Protein Sub-location | Introcelluar Protein |
| Category | |
| Disease | Breast Cancer |
| Gene Ensembl | ENSG00000072506 |
| Target Classification | N/A |
Pre-made anti-ABAD inhibitory monoclonal antibody(mab, blocking antibody inhibitor)-benchmark antibody for drug discovery and mechanism of action (MOA) research
Pre-made anti-ABAD monoclonal antibody(mab) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic). The anti-ABAD mab is expressed and produced by mammalian cell line as a benchmark reference therapeutic antibody for biological drug discovery items including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
| Antibody Name | Species | Format | Classified by tag | Detail |
| Anti-ABAD/HSD17B10 monoclonal antibody | Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine | mab | Detail |
Recombinant multi-species HCD2/ ABAD/ HSD17B10 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis
Genemedi produces Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine ABAD/HSD17B10 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
| Products Name | Species | Expression Platform | Detail |
| ABAD/HSD17B10 protein | Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine | Mammalian cell | Detail |
Pre-made HSD17B10 viral vector in GM Promise-ORFTM
| Cat No. | Products name | NM ID | Species | Type | Detail |
| vGMLP002970 | human HSD17B10 Lentivirus particle | NM_004493 | Human | Lentivirus particle | Detail |
| pGMLP002970 | human HSD17B10 Lentivirus plasmid | NM_004493 | Human | Lentivirus plasmid | Detail |
| pGMLPm000962 | mouse Hsd17b10 Lentivirus plasmid | NM_016763 | Mouse | Lentivirus plasmid | Detail |
| vGMLPm000962 | mouse Hsd17b10 Lentivirus particle | NM_016763 | Mouse | Lentivirus particle | Detail |
About Promise-ORFTM:
Discover the largest collection of ORF/cDNA expression clones from different species, including human, mouse, rat, and more with GeneMedi's Promise-ORFTM. Our collection of ORFs expression clones come in verified mammalian or viral vectors lentivirus, AAV, and adenovirus) and our Promise-ORFTM viral-ready expression vectors make it easy for you to improve viral vector packaging efficiency or directly transfect mammalian cells, resulting in stronger and easier expression detection. Click to search your GOI
If you want to obtain higher quantities of plasmids (mg), please visit GM TransExcellent Plasmid DNA Rapid Preparation Service.