RAB7A: Target/Biomarker Introduction, products summarized (antibody/ADC/bispecific/antigen/ORF vector/VLP) and disease/indication/condition/MOA for drug discovery and IVD
It's the GeneMedi's summary page for Target/Biomarker Introduction of RAB7A. The page also collects GeneMedi's different modalities and formats products for RAB7A in therapeutics/drug discovery and IVD diagnostics, which is including antibody, ADC, bispecific, antigen, ORF vector, VLP, etc. With GeneMedi's target-insight database-GM ITD database, the RAB7A target is also connected to human indications/diseases/conditions/MOA.
Target sublocation: Introcelluar Protein.
RAB family members are small, RAS-related GTP-binding proteins that are important regulators of vesicular transport. Each RAB protein targets multiple proteins that act in exocytic / endocytic pathways. This gene encodes a RAB family member that regulates vesicle traffic in the late endosomes and also from late endosomes to lysosomes. This encoded protein is also involved in the cellular vacuolation of the VacA cytotoxin of Helicobacter pylori. Mutations at highly conserved amino acid residues in this gene have caused some forms of Charcot-Marie-Tooth (CMT) type 2 neuropathies. [provided by RefSeq, Jul 2008]
| Target ID | GM-T14030 |
| Target Name | RAB7A |
| Gene ID | 7879,19349,29448,707280,404007,101085959,509970,100050015 |
| Gene Symbol and Synonyms | CMT2B,PRO2706,RAB7,RAB7A |
| Uniprot Accession | P51149,P09527,P18067,Q3T0F5 |
| Uniprot Entry Name | RAB7A_HUMAN,RAB7A_RAT,RAB7A_CANLF,RAB7A_BOVIN |
| Protein Sub-location | Introcelluar Protein |
| Category | Therapeutics Target |
| Disease | N/A |
| Gene Ensembl | ENSG00000075785 |
| Target Classification | N/A |
Pre-made anti-RAB7A inhibitory monoclonal antibody(mab, blocking antibody inhibitor)-benchmark antibody for drug discovery and mechanism of action (MOA) research
Pre-made anti-RAB7A monoclonal antibody(mab) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic). The anti-RAB7A mab is expressed and produced by mammalian cell line as a benchmark reference therapeutic antibody for biological drug discovery items including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
| Antibody Name | Species | Format | Classified by tag | Detail |
| Anti-RAB7A monoclonal antibody | Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine | mab | Therapeutics Target antibody | Detail |
Recombinant multi-species RAB7A/ PRO2706/ RAB7 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis
Genemedi produces Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine RAB7A protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
| Products Name | Species | Expression Platform | Detail |
| RAB7A protein | Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine | Mammalian cell | Detail |
Pre-made RAB7A viral vector in GM Promise-ORFTM
| Cat No. | Products name | NM ID | Species | Type | Detail |
| vGMLP004585 | human RAB7A Lentivirus particle | NM_004637 | Human | Lentivirus particle | Detail |
| pGMLP004585 | human RAB7A Lentivirus plasmid | NM_004637 | Human | Lentivirus plasmid | Detail |
| pGMAD000518 | house mouse Rab7 Adenovirus plasmid | NM_009005 | House Mouse | Adenovirus plasmid | Detail |
| pGMLPm001896 | mouse Rab7 Lentivirus plasmid | NM_009005 | Mouse | Lentivirus plasmid | Detail |
| vGMAD000518 | house mouse Rab7 Adenovirus particle | NM_009005 | House Mouse | Adenovirus particle | Detail |
| vGMLPm001896 | mouse Rab7 Lentivirus particle | NM_009005 | Mouse | Lentivirus particle | Detail |
About Promise-ORFTM:
Discover the largest collection of ORF/cDNA expression clones from different species, including human, mouse, rat, and more with GeneMedi's Promise-ORFTM. Our collection of ORFs expression clones come in verified mammalian or viral vectors lentivirus, AAV, and adenovirus) and our Promise-ORFTM viral-ready expression vectors make it easy for you to improve viral vector packaging efficiency or directly transfect mammalian cells, resulting in stronger and easier expression detection. Click to search your GOI
If you want to obtain higher quantities of plasmids (mg), please visit GM TransExcellent Plasmid DNA Rapid Preparation Service.