GNAQ: Target/Biomarker Introduction, products summarized (antibody/ADC/bispecific/antigen/ORF vector/VLP) and disease/indication/condition/MOA for drug discovery and IVD

It's the GeneMedi's summary page for Target/Biomarker Introduction of GNAQ. The page also collects GeneMedi's different modalities and formats products for GNAQ in therapeutics/drug discovery and IVD diagnostics, which is including antibody, ADC, bispecific, antigen, ORF vector, VLP, etc. With GeneMedi's target-insight database-GM ITD database, the GNAQ target is also connected to human indications/diseases/conditions/MOA.

Target sublocation: Transmembrane Protein.

This locus encodes a guanine nucleotide-binding protein. The encoded protein, an alpha subunit in the Gq class, couples a seven-transmembrane domain receptor to activation of phospolipase C-beta. Mutations at this locus have been associated with problems in platelet activation and aggregation. A related pseudogene exists on chromosome 2.[provided by RefSeq, Nov 2010]

Target IDGM-T12290
Target NameGNAQ
Gene ID2776,14682,81666,403928,101094708,536654,100063136
Gene Symbol and Synonyms1110005L02Rik,6230401I02Rik,CMAL,CMC1,Dsk1,Dsk10,G-ALPHA-q,Galphaq,GAQ,GNAQ,Gq,GqI,SWS
Uniprot AccessionP50148,P82471,Q28294
Uniprot Entry NameGNAQ_HUMAN,GNAQ_RAT,GNAQ_CANLF
Protein Sub-locationTransmembrane Protein
CategoryTherapeutics Target
DiseaseCancer
Gene EnsemblENSG00000156052
Target ClassificationTumor-associated antigen (TAA)


Pre-made anti-GNAQ inhibitory monoclonal antibody(mab, blocking antibody inhibitor)-benchmark antibody for drug discovery and mechanism of action (MOA) research

Pre-made anti-GNAQ benchmark inhibitory monoclonal antibody(mab, blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, FACS, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic). The anti-GNAQ mab is expressed and produced by mammalian cell line as a benchmark reference therapeutic antibody for biological drug discovery items including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.

Antibody NameSpeciesFormatClassified by tagDetail
Anti-GNAQ monoclonal antibodyHuman, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, EquinemabFACS/Biofunctional Antibody, Therapeutics Target antibodyDetail



Multi-species GNAQ/ CMC1/ G-ALPHA-q VLP (virus-like particle) for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

Genemedi produces Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine GNAQ VLP (virus-like particle) for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.

Products NameSpeciesExpression PlatformDetail
GNAQ VLP (virus-like particle)Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, EquineMammalian cellProducts Developing



Pre-made GNAQ viral vector in GM Promise-ORFTM

Cat No.Products nameNM IDSpeciesTypeDetail
pGMAP000230Human GNAQ Adenovirus plasmidBC057777HumanAdenovirus plasmidDetail
vGMAP000230Human GNAQ Adenovirus particleBC057777HumanAdenovirus particleDetail
pGMLPm002913mouse Gnaq Lentivirus plasmidNM_008139MouseLentivirus plasmidDetail
vGMLPm002913mouse Gnaq Lentivirus particleNM_008139MouseLentivirus particleDetail

About Promise-ORFTM:
Discover the largest collection of ORF/cDNA expression clones from different species, including human, mouse, rat, and more with GeneMedi's Promise-ORFTM. Our collection of ORFs expression clones come in verified mammalian or viral vectors lentivirus, AAV, and adenovirus) and our Promise-ORFTM viral-ready expression vectors make it easy for you to improve viral vector packaging efficiency or directly transfect mammalian cells, resulting in stronger and easier expression detection. Click to search your GOI

If you want to obtain higher quantities of plasmids (mg), please visit GM TransExcellent Plasmid DNA Rapid Preparation Service.