TNNT2: Target/Biomarker Introduction, products summarized (antibody/ADC/bispecific/antigen/ORF vector/VLP) and disease/indication/condition/MOA for drug discovery and IVD

It's the GeneMedi's summary page for Target/Biomarker Introduction of TNNT2. The page also collects GeneMedi's different modalities and formats products for TNNT2 in therapeutics/drug discovery and IVD diagnostics, which is including antibody, ADC, bispecific, antigen, ORF vector, VLP, etc. With GeneMedi's target-insight database-GM ITD database, the TNNT2 target is also connected to human indications/diseases/conditions/MOA.

Target sublocation: Introcelluar Protein.

This gene encodes the cardiac isoform of troponin T. The encoded protein is the tropomyosin-binding subunit of the troponin complex, which is located on the thin filament of striated muscles and regulates muscle contraction in response to alterations in intracellular calcium ion concentration. Mutations in this gene have been associated with familial hypertrophic cardiomyopathy as well as with dilated cardiomyopathy. [provided by RefSeq, May 2022]

Target IDGM-T05887
Target NameTNNT2
Gene ID7139,21956,24837,709882,403532,493940,286816,100146343
Gene Symbol and SynonymsCMD1D,CMH2,CMPD2,cTnT,Ctt,CTTG,LVNC6,RATCTTG,RCM3,TNNT2,Tnnt3,Tnt,TnTC
Uniprot AccessionP45379,P50753,P13789
Uniprot Entry NameTNNT2_HUMAN,TNNT2_RAT,TNNT2_BOVIN
Protein Sub-locationIntrocelluar Protein
CategoryTherapeutics Target, Diagnostics Biomarker
DiseaseN/A
Gene EnsemblENSG00000118194
Target ClassificationN/A


Pre-made anti-TNNT2 inhibitory monoclonal antibody(mab, blocking antibody inhibitor)-benchmark antibody for drug discovery and mechanism of action (MOA) research

Pre-made anti-TNNT2 monoclonal antibody(mab) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic). The anti-TNNT2 mab is expressed and produced by mammalian cell line as a benchmark reference therapeutic antibody for biological drug discovery items including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.

Antibody NameSpeciesFormatClassified by tagDetail
Anti-TNNT2 monoclonal antibodyHuman, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, EquinemabTherapeutics Target antibody, Diagnostic target antibodyDetail



Recombinant multi-species TNNT2/ CMD1D/ CMH2 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

Genemedi produces Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine TNNT2 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.

Products NameSpeciesExpression PlatformDetail
TNNT2 proteinHuman, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, EquineMammalian cellDetail



Pre-made TNNT2 viral vector in GM Promise-ORFTM

Cat No.Products nameNM IDSpeciesTypeDetail
pGMLP003317human TNNT2 Lentivirus plasmidNM_001001431HumanLentivirus plasmidDetail
vGMLP003317human TNNT2 Lentivirus particleNM_001001431HumanLentivirus particleDetail
pGMLPm000850mouse Tnnt2 Lentivirus plasmidNM_001130175MouseLentivirus plasmidDetail
vGMLPm000850mouse Tnnt2 Lentivirus particleNM_001130175MouseLentivirus particleDetail

About Promise-ORFTM:
Discover the largest collection of ORF/cDNA expression clones from different species, including human, mouse, rat, and more with GeneMedi's Promise-ORFTM. Our collection of ORFs expression clones come in verified mammalian or viral vectors lentivirus, AAV, and adenovirus) and our Promise-ORFTM viral-ready expression vectors make it easy for you to improve viral vector packaging efficiency or directly transfect mammalian cells, resulting in stronger and easier expression detection. Click to search your GOI

If you want to obtain higher quantities of plasmids (mg), please visit GM TransExcellent Plasmid DNA Rapid Preparation Service.