HDAC9: Target/Biomarker Introduction, products summarized (antibody/ADC/bispecific/antigen/ORF vector/VLP) and disease/indication/condition/MOA for drug discovery and IVD
It's the GeneMedi's summary page for Target/Biomarker Introduction of HDAC9. The page also collects GeneMedi's different modalities and formats products for HDAC9 in therapeutics/drug discovery and IVD diagnostics, which is including antibody, ADC, bispecific, antigen, ORF vector, VLP, etc. With GeneMedi's target-insight database-GM ITD database, the HDAC9 target is also connected to human indications/diseases/conditions/MOA.
Target sublocation: Introcelluar Protein.
Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene has sequence homology to members of the histone deacetylase family. This gene is orthologous to the Xenopus and mouse MITR genes. The MITR protein lacks the histone deacetylase catalytic domain. It represses MEF2 activity through recruitment of multicomponent corepressor complexes that include CtBP and HDACs. This encoded protein may play a role in hematopoiesis. Multiple alternatively spliced transcripts have been described for this gene but the full-length nature of some of them has not been determined. [provided by RefSeq, Jul 2008]
| Target ID | GM-T03687 |
| Target Name | HDAC9 |
| Gene ID | 9734,79221,687001,708314,482339,101085705,535415,106780857 |
| Gene Symbol and Synonyms | D030072B18Rik,HD7,HD7b,HD9,HDAC,HDAC7,HDAC7B,HDAC9,HDAC9B,HDAC9FL,HDRP,MITR,mKIAA0744,RGD1310748,RGD1563092,TWIST |
| Uniprot Accession | Q9UKV0 |
| Uniprot Entry Name | HDAC9_HUMAN |
| Protein Sub-location | Introcelluar Protein |
| Category | Therapeutics Target |
| Disease | N/A |
| Gene Ensembl | ENSG00000048052 |
| Target Classification | N/A |
Pre-made anti-HDAC9 inhibitory monoclonal antibody(mab, blocking antibody inhibitor)-benchmark antibody for drug discovery and mechanism of action (MOA) research
Pre-made anti-HDAC9 monoclonal antibody(mab) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic). The anti-HDAC9 mab is expressed and produced by mammalian cell line as a benchmark reference therapeutic antibody for biological drug discovery items including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
| Antibody Name | Species | Format | Classified by tag | Detail |
| Anti-HDAC9 monoclonal antibody | Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine | mab | Therapeutics Target antibody | Detail |
Recombinant multi-species HDAC9/ HD7/ HD7b protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis
Genemedi produces Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine HDAC9 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
| Products Name | Species | Expression Platform | Detail |
| HDAC9 protein | Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine | Mammalian cell | Detail |
Pre-made HDAC9 viral vector in GM Promise-ORFTM
| Cat No. | Products name | NM ID | Species | Type | Detail |
| pGMAD000394 | human HDAC9 Adenovirus plasmid | NM_178423.2 | Human | Adenovirus plasmid | Detail |
| vGMAD000394 | human HDAC9 Adenovirus particle | NM_178423.2 | Human | Adenovirus particle | Detail |
| pGMAD000554 | house mouse Hdac9 Adenovirus plasmid | NM_024124.3 | House Mouse | Adenovirus plasmid | Detail |
| pGMAD000555 | house mouse Hdac9 Adenovirus plasmid | NM_001271386.1 | House Mouse | Adenovirus plasmid | Detail |
| pGMLPm004329 | mouse Hdac9 Lentivirus plasmid | NM_001271386 | Mouse | Lentivirus plasmid | Detail |
| vGMAD000554 | house mouse Hdac9 Adenovirus particle | NM_024124.3 | House Mouse | Adenovirus particle | Detail |
| vGMAD000555 | house mouse Hdac9 Adenovirus particle | NM_001271386.1 | House Mouse | Adenovirus particle | Detail |
| vGMLPm004329 | mouse Hdac9 Lentivirus particle | NM_001271386 | Mouse | Lentivirus particle | Detail |
About Promise-ORFTM:
Discover the largest collection of ORF/cDNA expression clones from different species, including human, mouse, rat, and more with GeneMedi's Promise-ORFTM. Our collection of ORFs expression clones come in verified mammalian or viral vectors lentivirus, AAV, and adenovirus) and our Promise-ORFTM viral-ready expression vectors make it easy for you to improve viral vector packaging efficiency or directly transfect mammalian cells, resulting in stronger and easier expression detection. Click to search your GOI
If you want to obtain higher quantities of plasmids (mg), please visit GM TransExcellent Plasmid DNA Rapid Preparation Service.