CHI3L1: Target/Biomarker Introduction, products summarized (antibody/ADC/bispecific/antigen/ORF vector/VLP) and disease/indication/condition/MOA for drug discovery and IVD
It's the GeneMedi's summary page for Target/Biomarker Introduction of CHI3L1. The page also collects GeneMedi's different modalities and formats products for CHI3L1 in therapeutics/drug discovery and IVD diagnostics, which is including antibody, ADC, bispecific, antigen, ORF vector, VLP, etc. With GeneMedi's target-insight database-GM ITD database, the CHI3L1 target is also connected to human indications/diseases/conditions/MOA.
Target sublocation: Secreted Protein/Potential Cytokines.
Chitinases catalyze the hydrolysis of chitin, which is an abundant glycopolymer found in insect exoskeletons and fungal cell walls. The glycoside hydrolase 18 family of chitinases includes eight human family members. This gene encodes a glycoprotein member of the glycosyl hydrolase 18 family. The protein lacks chitinase activity and is secreted by activated macrophages, chondrocytes, neutrophils and synovial cells. The protein is thought to play a role in the process of inflammation and tissue remodeling. [provided by RefSeq, Sep 2009]
| Target ID | GM-SE0775 |
| Target Name | CHI3L1 |
| Gene ID | 1116,12654,89824,703401,490222,101100781,286869,100052556 |
| Gene Symbol and Synonyms | ASRT7,Brp39,CGP-39,CHI3L1,Chil1,CLP-1,GP-39,GP39,HC-gp39,hCGP-39,HCGP-3P,SPC-40,SPS-40,YK-40,YKL-40,YKL40,YYL-40 |
| Uniprot Accession | P36222,Q9WTV1,P30922 |
| Uniprot Entry Name | CH3L1_HUMAN,CH3L1_RAT,CH3L1_BOVIN |
| Protein Sub-location | Secreted Protein/Potential Cytokines |
| Category | Diagnostics Biomarker |
| Disease | Ovary Cancer, Acute kidney failure |
| Gene Ensembl | ENSG00000133048 |
| Target Classification | N/A |
Pre-made anti-CHI3L1 inhibitory monoclonal antibody(mab, blocking antibody inhibitor)-benchmark antibody for drug discovery and mechanism of action (MOA) research
Pre-made anti-CHI3L1 benchmark inhibitory monoclonal antibody(mab, blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic). The anti-CHI3L1 mab is expressed and produced by mammalian cell line as a benchmark reference therapeutic antibody for biological drug discovery items including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
| Antibody Name | Species | Format | Classified by tag | Detail |
| Anti-CHI3L1 monoclonal antibody | Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine | mab | FACS/Biofunctional Antibody, Diagnostic target antibody | Detail |
Recombinant multi-species CH3L1/ CHI3L1/ ASRT7 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis
Genemedi produces Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine CHI3L1 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
| Products Name | Species | Expression Platform | Detail |
| CHI3L1 protein | Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine | Mammalian cell | Detail |
Pre-made CHI3L1 viral vector in GM Promise-ORFTM
| Cat No. | Products name | NM ID | Species | Type | Detail |
| pGMLP001925 | human CHI3L1 Lentivirus plasmid | NM_001276.2 | Human | Lentivirus plasmid | Detail |
| vGMLP001925 | human CHI3L1 Lentivirus particle | NM_001276.2 | Human | Lentivirus particle | Detail |
| pGMLV000663 | Norway rat CHI3L1 Lentivirus plasmid | BC091365.1 | Norway Rat | Lentivirus plasmid | Detail |
| vGMLV000663 | Norway rat CHI3L1 Lentivirus particle | BC091365.1 | Norway Rat | Lentivirus particle | Detail |
| pGMLPm001986 | mouse Chil1 Lentivirus plasmid | NM_007695 | Mouse | Lentivirus plasmid | Detail |
| vGMLPm001986 | mouse Chil1 Lentivirus particle | NM_007695 | Mouse | Lentivirus particle | Detail |
About Promise-ORFTM:
Discover the largest collection of ORF/cDNA expression clones from different species, including human, mouse, rat, and more with GeneMedi's Promise-ORFTM. Our collection of ORFs expression clones come in verified mammalian or viral vectors lentivirus, AAV, and adenovirus) and our Promise-ORFTM viral-ready expression vectors make it easy for you to improve viral vector packaging efficiency or directly transfect mammalian cells, resulting in stronger and easier expression detection. Click to search your GOI
If you want to obtain higher quantities of plasmids (mg), please visit GM TransExcellent Plasmid DNA Rapid Preparation Service.