SERPINE2: Target/Biomarker Introduction, products summarized (antibody/ADC/bispecific/antigen/ORF vector/VLP) and disease/indication/condition/MOA for drug discovery and IVD
It's the GeneMedi's summary page for Target/Biomarker Introduction of SERPINE2. The page also collects GeneMedi's different modalities and formats products for SERPINE2 in therapeutics/drug discovery and IVD diagnostics, which is including antibody, ADC, bispecific, antigen, ORF vector, VLP, etc. With GeneMedi's target-insight database-GM ITD database, the SERPINE2 target is also connected to human indications/diseases/conditions/MOA.
Target sublocation: Secreted Protein/Potential Cytokines.
This gene encodes a member of the serpin family of proteins, a group of proteins that inhibit serine proteases. Thrombin, urokinase, plasmin and trypsin are among the proteases that this family member can inhibit. This gene is a susceptibility gene for chronic obstructive pulmonary disease and for emphysema. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2012]
| Target ID | GM-SE0469 |
| Target Name | SERPINE2 |
| Gene ID | 5270,20720,29366,707121,608930,101084306,282521,111767501 |
| Gene Symbol and Synonyms | B230326M24Rik,CRG,GDN,GDNPF,Gdnpn1,PAI-1,PI-7,PI7,PN-1,PN1,PNI,SERPINE1,SERPINE2,Spi4,Spin4 |
| Uniprot Accession | P07093,P07092 |
| Uniprot Entry Name | GDN_HUMAN,GDN_RAT |
| Protein Sub-location | Secreted Protein/Potential Cytokines |
| Category | |
| Disease | N/A |
| Gene Ensembl | ENSG00000135919 |
| Target Classification | N/A |
Pre-made anti-SERPINE2 inhibitory monoclonal antibody(mab, blocking antibody inhibitor)-benchmark antibody for drug discovery and mechanism of action (MOA) research
Pre-made anti-SERPINE2 benchmark inhibitory monoclonal antibody(mab, blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic). The anti-SERPINE2 mab is expressed and produced by mammalian cell line as a benchmark reference therapeutic antibody for biological drug discovery items including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
| Antibody Name | Species | Format | Classified by tag | Detail |
| Anti-SERPINE2 monoclonal antibody | Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine | mab | FACS/Biofunctional Antibody | Detail |
Recombinant multi-species GDN/ SERPINE2/ GDNPF protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis
Genemedi produces Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine SERPINE2 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
| Products Name | Species | Expression Platform | Detail |
| SERPINE2 protein | Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine | Mammalian cell | Detail |
Pre-made SERPINE2 viral vector in GM Promise-ORFTM
| Cat No. | Products name | NM ID | Species | Type | Detail |
| vGMLP002005 | human SERPINE2 Lentivirus particle | NM_006216.3 | Human | Lentivirus particle | Detail |
| pGMLV000820 | human SERPINE2 Lentivirus plasmid | NM_006216.3 | Human | Lentivirus plasmid | Detail |
| pGMLP002005 | human SERPINE2 Lentivirus plasmid | NM_006216.3 | Human | Lentivirus plasmid | Detail |
| vGMLV000820 | human SERPINE2 Lentivirus particle | NM_006216.3 | Human | Lentivirus particle | Detail |
| pGMLPm001725 | mouse Serpine2 Lentivirus plasmid | NM_009255 | Mouse | Lentivirus plasmid | Detail |
| vGMLPm001725 | mouse Serpine2 Lentivirus particle | NM_009255 | Mouse | Lentivirus particle | Detail |
About Promise-ORFTM:
Discover the largest collection of ORF/cDNA expression clones from different species, including human, mouse, rat, and more with GeneMedi's Promise-ORFTM. Our collection of ORFs expression clones come in verified mammalian or viral vectors lentivirus, AAV, and adenovirus) and our Promise-ORFTM viral-ready expression vectors make it easy for you to improve viral vector packaging efficiency or directly transfect mammalian cells, resulting in stronger and easier expression detection. Click to search your GOI
If you want to obtain higher quantities of plasmids (mg), please visit GM TransExcellent Plasmid DNA Rapid Preparation Service.