UBA52: Target/Biomarker Introduction, products summarized (antibody/ADC/bispecific/antigen/ORF vector/VLP) and disease/indication/condition/MOA for drug discovery and IVD
It's the GeneMedi's summary page for Target/Biomarker Introduction of UBA52. The page also collects GeneMedi's different modalities and formats products for UBA52 in therapeutics/drug discovery and IVD diagnostics, which is including antibody, ADC, bispecific, antigen, ORF vector, VLP, etc. With GeneMedi's target-insight database-GM ITD database, the UBA52 target is also connected to human indications/diseases/conditions/MOA.
Target sublocation: Transmembrane Protein.
Ubiquitin is a highly conserved nuclear and cytoplasmic protein that has a major role in targeting cellular proteins for degradation by the 26S proteosome. It is also involved in the maintenance of chromatin structure, the regulation of gene expression, and the stress response. Ubiquitin is synthesized as a precursor protein consisting of either polyubiquitin chains or a single ubiquitin moiety fused to an unrelated protein. This gene encodes a fusion protein consisting of ubiquitin at the N terminus and ribosomal protein L40 at the C terminus, a C-terminal extension protein (CEP). Multiple processed pseudogenes derived from this gene are present in the genome. [provided by RefSeq, Jul 2008]
| Target ID | GM-MP2368 |
| Target Name | UBA52 |
| Gene ID | 7311,22186,64156,720243,403722,100144608,615199,100071005 |
| Gene Symbol and Synonyms | CEP52,D8Ertd21e,Gm1863,HUBCEP52,L40,RPL40,Rps27a,UB-RPL40,UBA52,Ubb,Ubc,UBCEP2 |
| Uniprot Accession | P62987,P62986,P63050,P63052,P63048 |
| Uniprot Entry Name | RL40_HUMAN,RL40_RAT,RL40_FELCA,RL40_CANLF,RL40_BOVIN |
| Protein Sub-location | Transmembrane Protein |
| Category | |
| Disease | Lung Cancer, Diabetic Nephropathy |
| Gene Ensembl | ENSG00000221983 |
| Target Classification | N/A |
Pre-made anti-UBA52 inhibitory monoclonal antibody(mab, blocking antibody inhibitor)-benchmark antibody for drug discovery and mechanism of action (MOA) research
Pre-made anti-UBA52 benchmark inhibitory monoclonal antibody(mab, blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, FACS, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic). The anti-UBA52 mab is expressed and produced by mammalian cell line as a benchmark reference therapeutic antibody for biological drug discovery items including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
| Antibody Name | Species | Format | Classified by tag | Detail |
| Anti-UBA52 monoclonal antibody | Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine | mab | FACS/Biofunctional Antibody | Detail |
Multi-species RL40/ UBA52/ CEP52 VLP (virus-like particle) for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis
Genemedi produces Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine UBA52 VLP (virus-like particle) for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
| Products Name | Species | Expression Platform | Detail |
| UBA52 VLP (virus-like particle) | Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine | Mammalian cell | Products Developing |
Pre-made UBA52 viral vector in GM Promise-ORFTM
| Cat No. | Products name | NM ID | Species | Type | Detail |
| vGMLP003398 | human UBA52 Lentivirus particle | NM_001033930 | Human | Lentivirus particle | Detail |
| pGMLP003398 | human UBA52 Lentivirus plasmid | NM_001033930 | Human | Lentivirus plasmid | Detail |
| pGMLPm000660 | mouse Uba52 Lentivirus plasmid | NM_001348229 | Mouse | Lentivirus plasmid | Detail |
| vGMLPm000660 | mouse Uba52 Lentivirus particle | NM_001348229 | Mouse | Lentivirus particle | Detail |
About Promise-ORFTM:
Discover the largest collection of ORF/cDNA expression clones from different species, including human, mouse, rat, and more with GeneMedi's Promise-ORFTM. Our collection of ORFs expression clones come in verified mammalian or viral vectors lentivirus, AAV, and adenovirus) and our Promise-ORFTM viral-ready expression vectors make it easy for you to improve viral vector packaging efficiency or directly transfect mammalian cells, resulting in stronger and easier expression detection. Click to search your GOI
If you want to obtain higher quantities of plasmids (mg), please visit GM TransExcellent Plasmid DNA Rapid Preparation Service.