PAFAH1B2: Target/Biomarker Introduction, products summarized (antibody/ADC/bispecific/antigen/ORF vector/VLP) and disease/indication/condition/MOA for drug discovery and IVD
It's the GeneMedi's summary page for Target/Biomarker Introduction of PAFAH1B2. The page also collects GeneMedi's different modalities and formats products for PAFAH1B2 in therapeutics/drug discovery and IVD diagnostics, which is including antibody, ADC, bispecific, antigen, ORF vector, VLP, etc. With GeneMedi's target-insight database-GM ITD database, the PAFAH1B2 target is also connected to human indications/diseases/conditions/MOA.
Target sublocation: Transmembrane Protein.
Platelet-activating factor acetylhydrolase (PAFAH) inactivates platelet-activating factor (PAF) into acetate and LYSO-PAF. This gene encodes the beta subunit of PAFAH, the other subunits are alpha and gamma. Multiple alternatively spliced transcript variants have been described for this gene. [provided by RefSeq, Jan 2014]
| Target ID | GM-MP2229 |
| Target Name | PAFAH1B2 |
| Gene ID | 5049,18475,64189,703013,119881476,101085656,282514,100062620 |
| Gene Symbol and Synonyms | 2610005M20Rik,HEL-S-303,mus[b],PAFAH1B2,PAFAH1B2P68402,Pafahb |
| Uniprot Accession | P68402,O35264,P68401 |
| Uniprot Entry Name | PA1B2_HUMAN,PA1B2_RAT,PA1B2_BOVIN |
| Protein Sub-location | Transmembrane Protein |
| Category | |
| Disease | Cancer |
| Gene Ensembl | ENSG00000168092 |
| Target Classification | Tumor-associated antigen (TAA) |
Pre-made anti-PAFAH1B2 inhibitory monoclonal antibody(mab, blocking antibody inhibitor)-benchmark antibody for drug discovery and mechanism of action (MOA) research
Pre-made anti-PAFAH1B2 benchmark inhibitory monoclonal antibody(mab, blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, FACS, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic). The anti-PAFAH1B2 mab is expressed and produced by mammalian cell line as a benchmark reference therapeutic antibody for biological drug discovery items including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
| Antibody Name | Species | Format | Classified by tag | Detail |
| Anti-PAFAH1B2 monoclonal antibody | Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine | mab | FACS/Biofunctional Antibody | Detail |
Multi-species PA1B2/ PAFAH1B2/ HEL-S-303 VLP (virus-like particle) for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis
Genemedi produces Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine PAFAH1B2 VLP (virus-like particle) for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
| Products Name | Species | Expression Platform | Detail |
| PAFAH1B2 VLP (virus-like particle) | Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine | Mammalian cell | Products Developing |
Pre-made PAFAH1B2 viral vector in GM Promise-ORFTM
| Cat No. | Products name | NM ID | Species | Type | Detail |
| pGMLP002441 | human PAFAH1B2 Lentivirus plasmid | NM_002572 | Human | Lentivirus plasmid | Detail |
| vGMLP002441 | human PAFAH1B2 Lentivirus particle | NM_002572 | Human | Lentivirus particle | Detail |
| pGMLPm000746 | mouse Pafah1b2 Lentivirus plasmid | NM_008775 | Mouse | Lentivirus plasmid | Detail |
| vGMLPm000746 | mouse Pafah1b2 Lentivirus particle | NM_008775 | Mouse | Lentivirus particle | Detail |
About Promise-ORFTM:
Discover the largest collection of ORF/cDNA expression clones from different species, including human, mouse, rat, and more with GeneMedi's Promise-ORFTM. Our collection of ORFs expression clones come in verified mammalian or viral vectors lentivirus, AAV, and adenovirus) and our Promise-ORFTM viral-ready expression vectors make it easy for you to improve viral vector packaging efficiency or directly transfect mammalian cells, resulting in stronger and easier expression detection. Click to search your GOI
If you want to obtain higher quantities of plasmids (mg), please visit GM TransExcellent Plasmid DNA Rapid Preparation Service.