HCLS1: Target/Biomarker Introduction, products summarized (antibody/ADC/bispecific/antigen/ORF vector/VLP) and disease/indication/condition/MOA for drug discovery and IVD
It's the GeneMedi's summary page for Target/Biomarker Introduction of HCLS1. The page also collects GeneMedi's different modalities and formats products for HCLS1 in therapeutics/drug discovery and IVD diagnostics, which is including antibody, ADC, bispecific, antigen, ORF vector, VLP, etc. With GeneMedi's target-insight database-GM ITD database, the HCLS1 target is also connected to human indications/diseases/conditions/MOA.
Target sublocation: Transmembrane Protein.
Enables RNA polymerase II-specific DNA-binding transcription factor binding activity and protein kinase binding activity. Involved in several processes, including positive regulation of intracellular signal transduction; positive regulation of protein phosphorylation; and regulation of transcription, DNA-templated. Located in cytosol; nucleus; and plasma membrane. Part of transcription regulator complex. [provided by Alliance of Genome Resources, Apr 2022]
| Target ID | GM-MP2157 |
| Target Name | HCLS1 |
| Gene ID | 3059,15163,288077,714044,100684969,101084469,508445,100060842 |
| Gene Symbol and Synonyms | CTTNL,HCLS1,HS1,lckBP1,p75 |
| Uniprot Accession | P14317 |
| Uniprot Entry Name | HCLS1_HUMAN |
| Protein Sub-location | Transmembrane Protein |
| Category | |
| Disease | N/A |
| Gene Ensembl | ENSG00000180353 |
| Target Classification | N/A |
Pre-made anti-HCLS1 inhibitory monoclonal antibody(mab, blocking antibody inhibitor)-benchmark antibody for drug discovery and mechanism of action (MOA) research
Pre-made anti-HCLS1 benchmark inhibitory monoclonal antibody(mab, blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, FACS, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic). The anti-HCLS1 mab is expressed and produced by mammalian cell line as a benchmark reference therapeutic antibody for biological drug discovery items including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
| Antibody Name | Species | Format | Classified by tag | Detail |
| Anti-HCLS1 monoclonal antibody | Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine | mab | FACS/Biofunctional Antibody | Detail |
Multi-species HCLS1/ CTTNL/ HS1 VLP (virus-like particle) for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis
Genemedi produces Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine HCLS1 VLP (virus-like particle) for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
| Products Name | Species | Expression Platform | Detail |
| HCLS1 VLP (virus-like particle) | Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine | Mammalian cell | Products Developing |
Pre-made HCLS1 viral vector in GM Promise-ORFTM
| Cat No. | Products name | NM ID | Species | Type | Detail |
| pGMLP003756 | human HCLS1 Lentivirus plasmid | NM_005335 | Human | Lentivirus plasmid | Detail |
| pGMLP003907 | human HCLS1 Lentivirus plasmid | BC016758 | Human | Lentivirus plasmid | Detail |
| vGMLP003756 | human HCLS1 Lentivirus particle | NM_005335 | Human | Lentivirus particle | Detail |
| vGMLP003907 | human HCLS1 Lentivirus particle | BC016758 | Human | Lentivirus particle | Detail |
| pGMLPm002569 | mouse Hcls1 Lentivirus plasmid | NM_008225 | Mouse | Lentivirus plasmid | Detail |
| vGMLPm002569 | mouse Hcls1 Lentivirus particle | NM_008225 | Mouse | Lentivirus particle | Detail |
About Promise-ORFTM:
Discover the largest collection of ORF/cDNA expression clones from different species, including human, mouse, rat, and more with GeneMedi's Promise-ORFTM. Our collection of ORFs expression clones come in verified mammalian or viral vectors lentivirus, AAV, and adenovirus) and our Promise-ORFTM viral-ready expression vectors make it easy for you to improve viral vector packaging efficiency or directly transfect mammalian cells, resulting in stronger and easier expression detection. Click to search your GOI
If you want to obtain higher quantities of plasmids (mg), please visit GM TransExcellent Plasmid DNA Rapid Preparation Service.