ENO1: Target/Biomarker Introduction, products summarized (antibody/ADC/bispecific/antigen/ORF vector/VLP) and disease/indication/condition/MOA for drug discovery and IVD
It's the GeneMedi's summary page for Target/Biomarker Introduction of ENO1. The page also collects GeneMedi's different modalities and formats products for ENO1 in therapeutics/drug discovery and IVD diagnostics, which is including antibody, ADC, bispecific, antigen, ORF vector, VLP, etc. With GeneMedi's target-insight database-GM ITD database, the ENO1 target is also connected to human indications/diseases/conditions/MOA.
Target sublocation: Transmembrane Protein.
This gene encodes alpha-enolase, one of three enolase isoenzymes found in mammals. Each isoenzyme is a homodimer composed of 2 alpha, 2 gamma, or 2 beta subunits, and functions as a glycolytic enzyme. Alpha-enolase in addition, functions as a structural lens protein (tau-crystallin) in the monomeric form. Alternative splicing of this gene results in a shorter isoform that has been shown to bind to the c-myc promoter and function as a tumor suppressor. Several pseudogenes have been identified, including one on the long arm of chromosome 1. Alpha-enolase has also been identified as an autoantigen in Hashimoto encephalopathy. [provided by RefSeq, Jan 2011]
| Target ID | GM-MP0408 |
| Target Name | ENO1 |
| Gene ID | 2023,13806,24333,709378,479597,101093622,281141,100051879 |
| Gene Symbol and Synonyms | Eno-1,ENO1,ENO1-IT1,ENO1L1,HEL-S-17,MBP-1,MPB1,NNE,PPH |
| Uniprot Accession | P06733,P04764,Q9XSJ4 |
| Uniprot Entry Name | ENOA_HUMAN,ENOA_RAT,ENOA_BOVIN |
| Protein Sub-location | Transmembrane Protein |
| Category | |
| Disease | Dent disease |
| Gene Ensembl | ENSG00000074800 |
| Target Classification | N/A |
Pre-made anti-ENO1 inhibitory monoclonal antibody(mab, blocking antibody inhibitor)-benchmark antibody for drug discovery and mechanism of action (MOA) research
Pre-made anti-ENO1 benchmark inhibitory monoclonal antibody(mab, blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, FACS, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic). The anti-ENO1 mab is expressed and produced by mammalian cell line as a benchmark reference therapeutic antibody for biological drug discovery items including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
| Antibody Name | Species | Format | Classified by tag | Detail |
| Anti-ENO1 monoclonal antibody | Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine | mab | FACS/Biofunctional Antibody | Detail |
Multi-species ENOA/ ENO1/ ENO1L1 VLP (virus-like particle) for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis
Genemedi produces Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine ENO1 VLP (virus-like particle) for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
| Products Name | Species | Expression Platform | Detail |
| ENO1 VLP (virus-like particle) | Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine | Mammalian cell | Products Developing |
Pre-made ENO1 viral vector in GM Promise-ORFTM
| Cat No. | Products name | NM ID | Species | Type | Detail |
| pGMLP002092 | human ENO1 Lentivirus plasmid | NM_001428 | Human | Lentivirus plasmid | Detail |
| vGMLP002092 | human ENO1 Lentivirus particle | NM_001428 | Human | Lentivirus particle | Detail |
| pGMLPm005190 | mouse Eno1 Lentivirus plasmid | XM_006538525.2 | Mouse | Lentivirus plasmid | Detail |
| pGMLPm005326 | mouse Eno1 Lentivirus plasmid | NM_023119.2 | Mouse | Lentivirus plasmid | Detail |
| vGMLPm005190 | mouse Eno1 Lentivirus particle | XM_006538525.2 | Mouse | Lentivirus particle | Detail |
| vGMLPm005326 | mouse Eno1 Lentivirus particle | NM_023119.2 | Mouse | Lentivirus particle | Detail |
About Promise-ORFTM:
Discover the largest collection of ORF/cDNA expression clones from different species, including human, mouse, rat, and more with GeneMedi's Promise-ORFTM. Our collection of ORFs expression clones come in verified mammalian or viral vectors lentivirus, AAV, and adenovirus) and our Promise-ORFTM viral-ready expression vectors make it easy for you to improve viral vector packaging efficiency or directly transfect mammalian cells, resulting in stronger and easier expression detection. Click to search your GOI
If you want to obtain higher quantities of plasmids (mg), please visit GM TransExcellent Plasmid DNA Rapid Preparation Service.