AQP5: Target/Biomarker Introduction, products summarized (antibody/ADC/bispecific/antigen/ORF vector/VLP) and disease/indication/condition/MOA for drug discovery and IVD
It's the GeneMedi's summary page for Target/Biomarker Introduction of AQP5. The page also collects GeneMedi's different modalities and formats products for AQP5 in therapeutics/drug discovery and IVD diagnostics, which is including antibody, ADC, bispecific, antigen, ORF vector, VLP, etc. With GeneMedi's target-insight database-GM ITD database, the AQP5 target is also connected to human indications/diseases/conditions/MOA.
Target sublocation: Transmembrane Protein.
Aquaporin 5 (AQP5) is a water channel protein.? Aquaporins are a family of small integral membrane proteins related to the major intrinsic protein (MIP or AQP0). Aquaporin 5 plays a role in the generation of saliva, tears and pulmonary secretions. AQP0, AQP2, AQP5, and AQP6 are closely related and all map to 12q13. [provided by RefSeq, Jul 2008]
| Target ID | GM-MP0081 |
| Target Name | AQP5 |
| Gene ID | 362,11830,25241,711804,486551,101093196,782368,111767458 |
| Gene Symbol and Synonyms | AQP-5,AQP5,PPKB |
| Uniprot Accession | P55064,P47864 |
| Uniprot Entry Name | AQP5_HUMAN,AQP5_RAT |
| Protein Sub-location | Transmembrane Protein |
| Category | |
| Disease | N/A |
| Gene Ensembl | ENSG00000161798 |
| Target Classification | N/A |
Pre-made anti-AQP5 inhibitory monoclonal antibody(mab, blocking antibody inhibitor)-benchmark antibody for drug discovery and mechanism of action (MOA) research
Pre-made anti-AQP5 benchmark inhibitory monoclonal antibody(mab, blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, FACS, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic). The anti-AQP5 mab is expressed and produced by mammalian cell line as a benchmark reference therapeutic antibody for biological drug discovery items including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
| Antibody Name | Species | Format | Classified by tag | Detail |
| Anti-AQP5 monoclonal antibody | Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine | mab | FACS/Biofunctional Antibody | Detail |
Multi-species AQP5/ AQP-5/ PPKB VLP (virus-like particle) for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis
Genemedi produces Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine AQP5 VLP (virus-like particle) for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
| Products Name | Species | Expression Platform | Detail |
| AQP5 VLP (virus-like particle) | Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine | Mammalian cell | Products Developing |
Pre-made AQP5 viral vector in GM Promise-ORFTM
| Cat No. | Products name | NM ID | Species | Type | Detail |
| pGMLP003170 | human AQP5 Lentivirus plasmid | NM_001651 | Human | Lentivirus plasmid | Detail |
| vGMLP000566 | human AQP5 Lentivirus particle | NM_001651 | Human | Lentivirus particle | Detail |
| pGMLP000566 | human AQP5 Lentivirus plasmid | NM_001651 | Human | Lentivirus plasmid | Detail |
| vGMLP003170 | human AQP5 Lentivirus particle | NM_001651 | Human | Lentivirus particle | Detail |
| pGMAP000339 | Human AQP5 Adenovirus plasmid | BC032946 | Human | Adenovirus plasmid | Detail |
| vGMAP000339 | Human AQP5 Adenovirus particle | BC032946 | Human | Adenovirus particle | Detail |
| pGMAAV000118 | mouse Aqp5 AAV plasmid | NM_009701.4 | Mouse | AAV plasmid | Detail |
| vGMAAV000118 | mouse Aqp5 AAV particle | NM_009701.4 | Mouse | AAV particle | Detail |
About Promise-ORFTM:
Discover the largest collection of ORF/cDNA expression clones from different species, including human, mouse, rat, and more with GeneMedi's Promise-ORFTM. Our collection of ORFs expression clones come in verified mammalian or viral vectors lentivirus, AAV, and adenovirus) and our Promise-ORFTM viral-ready expression vectors make it easy for you to improve viral vector packaging efficiency or directly transfect mammalian cells, resulting in stronger and easier expression detection. Click to search your GOI
If you want to obtain higher quantities of plasmids (mg), please visit GM TransExcellent Plasmid DNA Rapid Preparation Service.