TM4SF1: Target/Biomarker Introduction, products summarized (antibody/ADC/bispecific/antigen/ORF vector/VLP) and disease/indication/condition/MOA for drug discovery and IVD

It's the GeneMedi's summary page for Target/Biomarker Introduction of TM4SF1. The page also collects GeneMedi's different modalities and formats products for TM4SF1 in therapeutics/drug discovery and IVD diagnostics, which is including antibody, ADC, bispecific, antigen, ORF vector, VLP, etc. With GeneMedi's target-insight database-GM ITD database, the TM4SF1 target is also connected to human indications/diseases/conditions/MOA.

Target sublocation: Introcelluar Protein.

The protein encoded by this gene is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. This encoded protein is a cell surface antigen and is highly expressed in different carcinomas. [provided by RefSeq, Jul 2008]

Target IDGM-IP1922
Target NameTM4SF1
Gene ID4071,17112,295061,711908,485710,101101157,533038,100050742
Gene Symbol and SynonymsH-L6,L6,M3S1,TAAL6,TM4SF1
Uniprot AccessionP30408
Uniprot Entry NameT4S1_HUMAN
Protein Sub-locationIntrocelluar Protein
Category
DiseaseCancer
Gene EnsemblENSG00000169908
Target ClassificationTumor-associated antigen (TAA)


Pre-made anti-TM4SF1 inhibitory monoclonal antibody(mab, blocking antibody inhibitor)-benchmark antibody for drug discovery and mechanism of action (MOA) research

Pre-made anti-TM4SF1 monoclonal antibody(mab) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic). The anti-TM4SF1 mab is expressed and produced by mammalian cell line as a benchmark reference therapeutic antibody for biological drug discovery items including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.

Antibody NameSpeciesFormatClassified by tagDetail
Anti-TM4SF1 monoclonal antibodyHuman, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, EquinemabDetail



Recombinant multi-species T4S1/ TM4SF1/ H-L6 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

Genemedi produces Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine TM4SF1 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.

Products NameSpeciesExpression PlatformDetail
TM4SF1 proteinHuman, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, EquineMammalian cellDetail



Pre-made TM4SF1 viral vector in GM Promise-ORFTM

Cat No.Products nameNM IDSpeciesTypeDetail
vGMLP004020human TM4SF1 Lentivirus particleBC008442HumanLentivirus particleDetail
vGMLP003951human TM4SF1 Lentivirus particleNM_014220HumanLentivirus particleDetail
pGMLP003951human TM4SF1 Lentivirus plasmidNM_014220HumanLentivirus plasmidDetail
pGMLP004020human TM4SF1 Lentivirus plasmidBC008442HumanLentivirus plasmidDetail
pGMLPm000458mouse Tm4sf1 Lentivirus plasmidNM_008536MouseLentivirus plasmidDetail
pGMLPm003950mouse Tm4sf1 Lentivirus plasmidNM_008536.3MouseLentivirus plasmidDetail
vGMLPm000458mouse Tm4sf1 Lentivirus particleNM_008536MouseLentivirus particleDetail
vGMLPm003950mouse Tm4sf1 Lentivirus particleNM_008536.3MouseLentivirus particleDetail

About Promise-ORFTM:
Discover the largest collection of ORF/cDNA expression clones from different species, including human, mouse, rat, and more with GeneMedi's Promise-ORFTM. Our collection of ORFs expression clones come in verified mammalian or viral vectors lentivirus, AAV, and adenovirus) and our Promise-ORFTM viral-ready expression vectors make it easy for you to improve viral vector packaging efficiency or directly transfect mammalian cells, resulting in stronger and easier expression detection. Click to search your GOI

If you want to obtain higher quantities of plasmids (mg), please visit GM TransExcellent Plasmid DNA Rapid Preparation Service.